Best TWAS P=1.1e-09 · Best GWAS P=6.89e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | ARL14EP | 0.43 | 0.36 | lasso | 3 | 0.37 | 1.8e-17 | -4.9 | -5.2 | 2.3e-07 | 0.84 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Thyroid | ARL14EP | 0.20 | 0.05 | lasso | 6 | 0.09 | 1.0e-07 | -5.8 | -5.5 | 3.7e-08 | 0.78 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C11orf46 | 0.02 | 0.02 | lasso | 2 | 0.02 | 5.9e-03 | -6.1 | -6.1 | 1.1e-09 | 1.00 | 0.00 | 0.83 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | C11orf46 | 0.12 | 0.06 | blup | 34 | 0.10 | 1.4e-09 | 2.9 | -5.4 | 6.8e-08 | 0.71 | 0.57 | 0.43 | FALSE |