Best TWAS P=3.02e-10 · Best GWAS P=5.37e-11 conditioned to 9.31e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | CTTN | 0.16 | 0.07 | lasso | 4 | 0.08 | 2.6e-05 | -4.6 | -5.9 | 3.8e-09 | 0.11 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Artery Tibial | CTTN | 0.18 | 0.08 | enet | 23 | 0.11 | 1.1e-08 | -6.5 | -6.1 | 1.4e-09 | 0.04 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | CTTN | 0.02 | 0.01 | blup | 32 | 0.02 | 3.8e-03 | -3.9 | -5.8 | 8.0e-09 | 0.13 | 0.01 | 0.71 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CTTN | 0.06 | 0.06 | lasso | 3 | 0.06 | 8.2e-07 | -6.2 | -6.3 | 3.0e-10 | 0.13 | 0.02 | 0.98 | TRUE |
| 5 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | PPFIA1 | 0.11 | 0.05 | blup | 69 | 0.05 | 1.7e-02 | -6.2 | 5.8 | 5.7e-09 | -0.04 | 0.02 | 0.41 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | CTTN | 0.05 | 0.06 | blup | 32 | 0.04 | 3.5e-05 | -6.3 | -6.0 | 1.9e-09 | 0.12 | 0.01 | 0.99 | FALSE |