TWAS
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Traits
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Traits
:
Lung FEV1/FVC ratio
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chr11:110,202,535-110,833,266
Best TWAS P=1.14e-08 · Best GWAS P=1.48e-12 conditioned to 3.82e-07
110.2M
110.3M
110.4M
110.5M
110.6M
110.7M
110.8M
0
2
4
6
8
10
12
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
ARHGAP20
0.04
0.01
lasso
2
0.02
0.0021
-5.1
-5.7
1.1e-08
0.44
0.05
0.21
TRUE