Best TWAS P=1.63e-14 · Best GWAS P=1.4e-13 conditioned to 0.0344
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ARHGAP42 | 0.04 | 0.01 | blup | 266 | 0.02 | 1.1e-04 | -3.8 | 7.7 | 1.6e-14 | -0.58 | 0.08 | 0.77 | TRUE |
| 5 | GTEx | Cells Transformed fibroblasts | ARHGAP42 | 0.15 | 0.10 | enet | 20 | 0.08 | 2.6e-06 | -4.6 | 7.1 | 1.1e-12 | -0.55 | 0.46 | 0.50 | TRUE |
| 3 | GTEx | Artery Tibial | ARHGAP42 | 0.24 | 0.24 | lasso | 4 | 0.24 | 2.4e-18 | 6.5 | 6.4 | 1.9e-10 | -0.35 | 0.69 | 0.31 | FALSE |
| 1 | CommonMind | Brain Pre-frontal Cortex | ARHGAP42 | 0.08 | 0.03 | enet | 14 | 0.05 | 2.8e-06 | 4.8 | 6.3 | 3.5e-10 | -0.74 | 0.03 | 0.97 | FALSE |
| 4 | GTEx | Artery Tibial | TMEM133 | 0.26 | 0.25 | enet | 28 | 0.27 | 1.3e-21 | 6.5 | 6.1 | 1.1e-09 | -0.40 | 0.60 | 0.40 | FALSE |
| 2 | GTEx | Artery Aorta | ARHGAP42 | 0.22 | 0.15 | enet | 18 | 0.19 | 1.7e-10 | 5.9 | 5.9 | 4.5e-09 | -0.54 | 0.67 | 0.32 | FALSE |