TWAS hub - ARHGAP20

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.1900	0.070	0.0024	0.260	NA	0.197	NA	0.220	2.4e-07	NA	8.9e-06	NA	2.4e-06
2	GTEx	Brain Cerebellum	0.2240	0.083	0.0039	0.058	NA	0.096	NA	0.036	8.4e-03	NA	9.1e-04	NA	3.1e-02
3	TCGA	Lung Squamous Cell Carcinoma	0.0364	0.025	0.0035	0.007	0.018	0.020	NA	0.020	4.9e-02	0.0031	2.2e-03	NA	2.1e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Wears glasses or contact lenses	8.3	9.6	11.1	-2.7	-3.3	3.2
Medication: Seretide 50 evohaler	4.1	4.7	5.6	-2.4	-2.0	2.2
Medication for hormone replacement therapy	3.9	4.3	9.3	1.8	3.1	-0.7
Loud music exposure frequency	3.7	4.0	6.6	2.6	2.1	-1.0
Lupus	3.4	5.2	8.7	1.9	2.9	-1.8
Waist circumference	3.3	12.0	17.5	-3.7	-4.2	2.2
Hair/balding pattern: Pattern 2	3.3	4.2	8.1	0.7	2.0	-2.9
Medication: Gliclazide	3.3	3.8	5.8	-2.4	-1.8	1.5
Ever had prostate specific antigen (PSA) test	3.1	3.6	6.2	2.1	2.5	-0.4
Major Depression (MDD)	3.0	3.6	7.1	1.4	1.3	-2.7
Body Mass Index (BMI) (2010)	3.0	4.1	6.8	-1.7	-2.6	1.6
Age when periods started (menarche)	3.0	7.2	8.4	2.4	2.9	-2.8
Medication: Simvastatin	3.0	4.3	9.4	-1.6	-3.1	1.0
Ever had stillbirth, spontaneous miscarriage or termination	3.0	3.2	5.7	1.3	2.4	-1.5
Rheumatoid Arthritis	2.9	3.9	5.1	2.3	2.2	-1.4
Trunk fat percentage	2.9	11.5	16.3	-3.7	-4.0	2.1
Leg fat percentage (right)	2.8	10.0	15.7	-3.2	-4.0	2.0
Body fat percentage	2.7	10.8	16.2	-3.5	-4.0	2.0
Commuting to job workplace: Public transport	2.7	3.3	5.5	-0.2	-2.3	2.1
Alcohol drinker status: Never	2.7	3.3	5.1	1.6	2.2	-1.5
High blood pressure (mother)	2.6	3.7	5.2	-2.3	-1.9	1.4
Alcohol usually taken with meals	2.6	4.1	7.7	1.3	2.8	-1.7
Medication: Ramipril	2.6	3.3	5.7	-1.8	-2.4	0.9
Ever taken oral contraceptive pill	2.6	2.9	5.0	1.2	2.2	-1.5
Waist Hip Ratio (WHR)	2.5	11.2	16.3	-3.4	-4.0	2.4
Lung FEV1/FVC ratio	2.5	12.8	32.6	2.2	0.9	-5.7
Medication: Ibuprofen (e.g. Nurofen)	2.5	3.2	4.5	-1.8	-1.3	2.1
Arm fat percentage (right)	2.4	9.5	15.2	-3.5	-3.9	1.2
Townsend deprivation index at recruitment	2.3	3.2	4.8	-2.2	-1.5	1.6
Trunk fat mass	2.3	9.7	13.8	-3.2	-3.7	2.2
Pulse wave reflection index	2.3	2.8	3.3	1.8	1.8	-1.4
Leg fat percentage (left)	2.3	8.4	14.6	-2.9	-3.8	1.5
Illnesses of siblings	2.2	3.1	5.3	1.5	2.3	-1.3
Ever depressed for a whole week	2.2	2.7	4.2	0.9	2.0	-1.8
Alzheimer’s Disease (in mother)	2.1	2.5	4.7	1.6	2.2	-0.5
Serious illness, injury or assault of a close relative in last 2 years	2.1	2.4	4.1	1.4	2.0	-1.0
Medication: Blood pressure	2.1	3.7	5.0	-1.2	-2.2	2.1
Type 2 Diabetes (T2D) (2012)	2.0	2.3	5.2	-1.0	-2.3	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	2.0	6.4	9.4	2.4	2.0	-3.1
Number of children fathered	2.0	2.3	6.0	2.4	-0.4	-0.9
Whole body fat mass	2.0	8.2	12.0	-3.0	-3.5	1.8
Arm fat percentage (left)	2.0	8.0	12.9	-3.1	-3.6	1.1
Qualifications: nursing, teaching	2.0	3.1	5.0	1.1	1.8	-2.2
Number of incorrect matches in round	1.9	3.2	4.8	-2.2	-2.0	0.7
Illnesses of mother	1.9	2.4	4.5	1.4	0.8	-2.1
Primary Biliary Cirrhosis	1.8	2.6	4.4	-1.4	-2.1	1.2
Relative age voice broke	1.8	2.8	3.2	1.7	1.5	-1.8
Pulse rate	1.8	3.0	3.9	-2.0	-1.5	1.7
Peak expiratory flow (PEF)	1.8	4.1	10.0	1.2	-0.8	-3.2
Supplements: Fish oil (including cod liver oil)	1.8	2.3	3.3	1.2	1.8	-1.5
HDL Cholesterol	1.7	2.9	4.2	2.1	1.3	-1.7
Hand grip strength (right)	1.7	4.6	8.2	2.9	2.0	-1.2
Leg fat mass (right)	1.7	6.5	10.2	-2.6	-3.2	1.6
Chest pain or discomfort	1.7	2.4	4.0	-1.8	0.0	2.0
Knee pain experienced in last month	1.7	2.6	3.9	-2.0	-1.4	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	3.6	1.5	0.5	-1.9
Myopia	1.7	2.5	3.8	-1.9	-1.9	0.3
Financial difficulties in last 2 years	1.6	2.2	5.6	-2.4	-0.9	0.4
Noisy workplace	1.6	2.0	3.5	-1.9	-1.3	1.0
Arm fat mass (right)	1.6	6.5	9.6	-2.8	-3.1	1.4
Medication: Paracetamol	1.6	2.6	6.2	-2.5	-0.6	1.2
Illnesses of father: Heart disease	1.6	2.2	3.6	-1.9	-1.5	0.9
Guilty feelings	1.6	2.4	5.9	-2.4	-1.2	0.2
Pack years of smoking	1.6	2.3	2.9	-1.7	-1.2	1.6
Leg fat mass (left)	1.6	6.1	9.8	-2.5	-3.1	1.4
Exposure to tobacco smoke outside home	1.5	2.0	2.9	-1.4	-1.1	1.7
Tinnitus: Yes, now most or all of the time	1.5	1.7	2.6	1.6	0.5	-1.5
Average weekly fortified wine intake	1.4	1.7	3.7	-0.3	1.9	1.1
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.2	5.6	-1.9	-2.4	0.7
Fluid intelligence score	1.4	3.0	7.1	2.7	1.1	-0.8
Worrier / anxious feelings	1.4	2.6	3.1	-1.5	-1.5	1.8
Medication: Cholesterol lowering	1.4	2.1	3.9	-1.1	-2.0	1.1
Pulse wave Arterial Stiffness index	1.4	1.6	2.4	1.0	1.2	-1.6
Medication for cholesterol, blood pressure or diabetes	1.4	2.4	4.6	0.8	2.1	-1.4
Mouth/teeth dental problems: Loose teeth	1.4	1.7	3.1	-1.2	-1.8	-0.8
Commuting to job workplace: Walk	1.4	1.5	2.3	0.4	-1.5	1.4
Medication: Aspirin	1.4	1.8	4.0	-0.7	-2.0	1.0
HbA1C	1.3	1.4	3.8	-0.7	0.1	2.0
LDL Cholesterol	1.3	2.1	4.9	0.4	1.1	-2.2
Pack years adult smoking proportion	1.3	2.1	2.7	-1.6	-1.0	1.6
Serious illness, injury or assault to yourself	1.3	1.6	2.5	0.5	1.4	-1.6
Body mass index (BMI)	1.3	5.4	9.1	-2.4	-3.0	1.1
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	3.1	-1.7	-1.4	0.5
Worry too long after embarrassment	1.3	2.1	5.2	-1.0	-0.4	2.3
Pulse wave peak to peak time	1.3	1.5	2.5	-0.8	-1.1	1.6
Pulse rate, automated reading	1.3	4.1	5.2	-2.3	-1.7	2.1
Arm fat mass (left)	1.3	5.4	7.7	-2.6	-2.8	1.2
Risk taking	1.3	2.0	5.4	0.7	-0.1	-2.3
Hand grip strength (left)	1.2	3.1	6.1	2.5	1.7	-0.7
Systolic blood pressure, automated reading	1.2	3.5	9.1	-0.8	-3.0	0.8
Supplements: Zinc	1.2	1.3	1.6	-1.3	-1.2	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.8	6.0	-1.5	-2.5	0.1
Time employed in main current job	1.2	1.4	3.5	0.9	-0.3	1.9
Medication: Lansoprazole	1.2	1.3	1.9	1.3	1.4	-0.5
Glaucoma (self-reported)	1.2	1.5	3.6	-1.9	-0.9	-0.3
Angina (self-reported)	1.2	1.6	4.5	0.2	2.1	-0.4
Smoking status: Current	1.2	2.0	3.4	-1.8	-1.3	0.9
Heart disease (siblings)	1.2	1.5	2.0	-0.7	-1.4	1.4
Irritable Bowel Disease (IBD)	1.1	2.6	4.1	-1.3	-2.0	1.4
BMI	1.1	6.6	11.8	-2.6	-3.4	1.0
Diabetes (mother)	1.1	1.5	2.8	-1.7	-1.1	-0.5
Current tobacco smoking	1.1	1.8	3.0	-1.7	-1.1	1.1
Pain all over the body in last month	1.1	1.1	2.2	1.0	1.5	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.8	3.6	-0.7	1.9	-1.0
Migraine (self-reported)	1.1	1.4	1.7	-1.3	-1.2	1.1
Commuting to job workplace: Car/motor vehicle	1.1	1.3	2.9	0.3	1.7	-0.9
Illnesses of father: High blood pressure	1.1	1.3	1.7	0.9	1.2	-1.3
Bipolar Disorder or Schizophrenia	1.0	2.5	5.0	1.1	1.2	-2.2
Weight	1.0	5.1	6.1	-2.2	-2.5	2.1
Father’s age at death	1.0	1.4	2.6	1.3	1.6	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.1	3.0	-0.7	-1.7	0.2
Friendships satisfaction	1.0	1.2	2.4	-1.6	-1.1	0.5
Ulcerative Colitis (UC)	0.9	1.6	2.2	-1.1	-1.5	1.2
Prostate Cancer	0.9	1.2	3.5	-0.3	-1.9	0.4
Fasting Glucose	0.9	1.1	2.5	-0.2	-0.9	1.6
Stomach or abdominal pain in last month	0.9	1.1	1.4	-1.2	-1.0	0.9
High blood pressure (siblings)	0.9	1.2	2.6	-0.8	-1.6	0.7
Medication for pain relief, constipation, heartburn	0.9	1.6	2.4	1.6	1.1	-1.0
Heart disease (mother)	0.9	1.1	2.8	-0.5	-0.3	1.7
Medication: Aspirin	0.9	1.2	2.8	-0.4	-1.7	0.8
Smoking status: Previous	0.9	1.3	2.4	1.1	-0.7	-1.5
Handedness (chirality/laterality): Left-handed	0.9	1.1	3.0	0.4	1.7	-0.4
Eye problems/disorders: Glaucoma	0.9	1.1	2.7	-1.7	-0.6	-0.4
Number of operations (self-reported)	0.9	1.4	2.6	1.6	0.9	-0.9
Depression (Nagel 2018)	0.8	1.1	2.0	1.1	1.4	0.4
Schizophrenia (2018)	0.8	1.7	4.1	0.8	0.5	-2.0
Alzheimer’s Disease (including proxy)	0.8	1.1	1.8	1.2	1.3	0.2
Ovarian Cancer	0.8	1.0	1.1	1.1	1.0	-1.0
Schizophrenia (2014)	0.8	1.8	5.3	0.3	0.3	-2.3
Smoking Status	0.8	1.8	4.8	-0.8	-2.2	0.1
Ever used hormone-replacement therapy (HRT)	0.8	1.0	1.6	1.2	1.3	0.1
Angina	0.8	1.0	3.0	0.1	1.7	-0.2
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	1.9	0.8	1.4	-0.7
Forced vital capacity (FVC), Best measure	0.8	2.8	3.5	1.9	1.7	-1.3
Wheeze or whistling in the chest in last year	0.8	1.4	2.5	-1.6	-1.2	0.4
Eye problems/disorders: None of the above	0.8	1.0	2.3	0.7	-0.3	1.5
Medication: Ibuprofen	0.8	1.0	1.2	-1.0	-0.9	1.1
Medication for cholesterol	0.8	1.2	1.8	-1.1	-0.8	1.3
Osteoarthritis (self-reported)	0.8	1.1	3.1	-0.2	-0.3	1.8
High cholesterol (Self-reported)	0.8	1.4	3.7	-0.4	-1.9	0.4
Average weekly beer plus cider intake	0.8	1.2	3.0	0.7	0.3	-1.7
Fractured/broken bones in last 5 years	0.8	1.0	1.8	0.6	0.8	-1.4
Verbal and Numeric Reasoning (VNR)	0.7	1.7	3.9	2.0	1.2	-0.0
Breast Cancer	0.7	1.8	2.7	1.6	1.6	-0.1
Triglycerides	0.7	1.2	2.8	-1.7	-0.7	0.6
Systolic Blood Pressure	0.7	3.5	6.4	-2.0	-2.5	0.6
Medication: Metformin	0.7	1.0	1.6	-1.3	-0.9	0.8
High blood pressure	0.7	2.0	5.2	-0.5	-2.3	0.8
Past tobacco smoking	0.7	1.3	2.7	0.2	1.6	1.1
Hearing difficulty/problems with background noise	0.7	1.0	2.0	1.0	1.4	0.2
Depression (self-reported)	0.7	0.8	1.3	-0.7	1.1	-0.8
Length of working week for main job	0.7	0.7	1.7	-0.6	-0.3	-1.3
Medication: Amlodipine	0.7	1.0	1.8	-0.9	-1.4	0.5
Number of full brothers	0.7	0.9	1.8	-1.3	-0.2	0.9
Asthma (self-reported)	0.7	1.5	3.6	-1.9	-0.8	0.4
Osteoporosis (self-reported)	0.7	0.8	1.3	-1.0	0.4	1.1
Number of self-reported non-cancer illnesses	0.7	1.2	2.5	-0.8	-0.6	1.6
Medication: Bendroflumethiazide	0.7	1.0	2.3	-0.7	-1.5	0.4
Vascular/heart problems diagnosed by doctor	0.7	2.0	4.9	0.5	2.2	-0.8
Bipolar Disorder (2018)	0.6	1.0	1.3	0.8	1.1	-1.0
Reaction Time	0.6	1.1	1.7	-1.0	-1.3	0.7
Age at First Birth	0.6	0.9	2.1	0.8	-1.5	0.3
Hypothyroidism (self reported)	0.6	1.3	1.8	1.3	1.0	-1.1
Qualifications: None of the above	0.6	1.3	2.6	-0.5	-1.6	1.0
Hip circumference	0.6	2.5	3.1	-1.6	-1.8	1.3
Asthma	0.6	1.2	2.9	-1.7	-0.6	0.5
Prospective memory result	0.6	0.7	1.5	0.7	1.2	-0.5
Headache pain in last month	0.6	1.0	2.6	-0.3	-0.6	1.6
Medication: Ventolin 100micrograms inhaler	0.6	0.7	1.8	-0.5	-0.2	1.4
Health satisfaction	0.6	0.7	1.9	0.3	-0.5	1.4
Mean time to correctly identify matches	0.6	1.1	1.7	-0.9	-1.3	1.0
Hypertension (Self-reported)	0.6	1.5	4.2	-0.2	-2.0	0.6
Average weekly champagne plus white wine intake	0.6	0.9	1.9	-1.4	-0.5	-0.7
Medication: Paracetamol	0.6	0.9	2.5	-1.6	0.2	0.4
Diastolic blood pressure, automated reading	0.6	1.9	4.6	-0.7	-2.1	0.7
Unable to work because of sickness or disability	0.6	0.8	1.4	-1.2	1.0	-0.2
Alcohol drinker status: Previous	0.6	0.6	0.8	0.6	0.9	-0.9
Crohns Disease (2012)	0.5	0.8	1.4	-1.2	-0.9	0.4
Heel T-Score	0.5	3.7	7.0	-2.0	-2.6	-0.5
Cardiovascular Disease	0.5	1.7	3.7	-1.1	-1.9	-0.2
Average weekly spirits intake	0.5	0.6	1.3	0.3	0.7	1.1
Frequency of depressed mood in last 2 weeks	0.5	0.6	1.5	-0.6	0.2	1.2
Severe depression (siblings)	0.5	0.6	1.0	-0.6	-0.5	1.0
Multivitamins +/- minerals	0.5	0.6	0.9	0.9	0.5	-0.9
Heart attack	0.5	0.6	0.9	0.9	1.0	-0.2
Falls in the last year	0.5	0.7	1.6	0.7	-0.2	-1.3
Number of live births	0.5	0.7	1.1	1.0	1.0	-0.3
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	3.8	1.1	-0.1	-1.9
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.1	-0.4	-1.0	0.8
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.4	0.2	-1.2	-0.7
Blood clot in the leg (DVT)	0.5	0.7	1.2	0.5	0.8	1.1
Shortness of breath walking on level ground	0.5	0.5	1.4	-1.2	-0.5	0.1
Age at last live birth	0.5	0.8	1.2	0.6	1.1	-0.9
Illnesses of siblings: Diabetes	0.5	0.6	0.8	-0.9	-0.9	0.4
Loneliness, isolation	0.5	0.6	1.9	0.2	1.4	0.1
Mineral and other dietary supplements	0.5	0.7	1.0	-0.6	-1.0	0.9
Financial situation satisfaction	0.5	0.6	1.2	0.5	0.7	-1.1
Medication: Atorvastatin	0.5	0.6	1.2	0.4	0.7	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.0	0.5	0.7	1.0
Depressed Affect (Nagel 2018)	0.4	0.9	1.3	1.1	0.8	-0.8
Crohns Disease (2017)	0.4	0.9	1.5	-0.8	-1.2	0.7
Hair Pigment	0.4	11.9	14.1	-3.0	-3.8	3.5
Sensitivity / hurt feelings	0.4	0.7	1.9	0.2	0.3	1.4
Relative age of first facial hair	0.4	0.9	1.4	0.8	1.2	-0.8
Diabetes (father)	0.4	0.5	1.4	-0.2	0.1	1.2
Had menopause	0.4	0.5	0.9	0.6	0.5	1.0
Qualifications: A levels/AS levels or equivalent	0.4	0.9	1.5	0.3	1.2	-1.0
Mouth/teeth dental problems: Dentures	0.4	0.7	1.8	-0.3	-1.3	0.6
Exposure to tobacco smoke at home	0.4	0.5	1.1	-0.4	-1.1	0.4
Breastfed as a baby	0.4	0.4	0.9	-0.9	-0.6	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.4	-1.2	0.5	-0.3
Comparative height size at age 10	0.4	2.4	3.1	-1.1	-1.7	1.8
Leg pain on walking	0.4	0.5	0.8	0.1	0.8	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	1.1	-0.2	0.4	-1.1
Eye problems/disorders: Cataract	0.4	0.5	1.0	-1.0	0.1	-0.6
Illnesses of father: None of the above (group 1)	0.4	0.5	1.0	1.0	0.7	-0.1
Medication: Lisinopril	0.4	0.5	1.3	0.3	0.3	-1.1
Ever smoked	0.4	0.7	1.5	-0.3	-0.8	-1.2
Commuting to job workplace: Cycle	0.4	0.5	0.6	-0.6	-0.6	0.8
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.7	0.8	0.9	-0.1
Schizophrenia vs Biploar Disorder	0.3	0.4	0.8	0.5	0.3	-0.9
Blood White Count	0.3	2.3	4.5	-2.1	-1.0	1.2
Height	0.3	5.2	10.6	1.7	1.5	3.3
Allergy or Eczema	0.3	0.7	2.1	-1.4	0.1	0.4
Respiratory disease	0.3	0.6	0.9	-0.9	0.5	0.9
Number of treatments/medications taken	0.3	0.6	1.0	0.0	-1.0	0.9
Hearing difficulty/problems: Yes	0.3	0.5	0.6	0.6	0.8	0.6
Vitamin and mineral supplements	0.3	0.3	0.9	-0.9	-0.3	0.3
Impedance of leg (right)	0.3	1.4	2.0	-1.4	-0.6	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.3	-0.1	0.2	1.1
Taking other prescription medications	0.3	0.4	0.6	-0.8	-0.5	0.6
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.8	-0.2	0.9	0.1
Qualifications: CSEs or equivalent	0.3	0.4	0.6	-0.4	0.8	-0.6
Sitting height	0.3	2.1	3.3	1.0	1.8	1.4
Had other major operations	0.3	0.4	0.7	0.5	-0.4	0.8
Mouth/teeth dental problems	0.3	0.5	1.3	-0.3	1.1	-0.0
Allergy	0.3	0.6	0.9	0.8	-0.9	-0.6
Alcohol intake versus 10 years previously	0.3	0.4	1.0	0.5	0.1	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	0.9	-0.7	-0.0	0.9
Happiness	0.3	0.3	0.8	0.4	0.9	0.0
Hair/balding pattern: Pattern 4	0.3	0.7	1.5	0.4	0.7	1.2
Birth weight	0.3	0.6	1.6	-1.3	0.2	-0.2
Qualifications: College or University degree	0.3	1.0	2.0	0.0	1.4	-1.0
Emphysema/chronic bronchitis	0.3	0.3	0.5	0.7	0.6	-0.1
Overall health rating	0.3	0.6	1.6	-0.4	-0.5	1.2
Had major operations	0.3	0.3	0.6	-0.3	-0.5	0.8
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.8	-0.2	-0.9	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.2	0.0	0.8	-1.1
Ever had bowel cancer screening	0.3	0.3	0.9	0.2	0.3	1.0
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.3	1.1	0.4	0.0
Pain type(s) experienced in last month: Hip pain	0.3	0.3	0.6	0.4	0.8	-0.5
Coronary Artery Disease (CAD)	0.2	0.2	0.4	-0.4	-0.6	-0.1
Mean Putamen Volume	0.2	0.2	0.3	-0.0	0.5	-0.6
Blood Red Count	0.2	2.1	3.8	1.3	0.8	-1.9
Chronotype (morning person)	0.2	0.4	0.7	-0.6	0.5	0.8
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.7	-0.3	0.9	-0.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.3	0.5	-0.1	0.6
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.1	-1.0	0.5	0.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.4	0.2	-0.6	-0.4
Medication: Levothyroxine sodium	0.2	0.4	0.9	0.4	0.3	-1.0
Chronic bronchitis/emphysema (father)	0.2	0.3	0.5	0.7	0.4	0.4
Neuroticism score	0.2	0.3	1.0	-0.2	-0.1	1.0
Standing height	0.2	2.0	4.8	0.4	1.1	2.2
Birth weight of first child	0.2	0.3	0.5	-0.7	-0.6	0.4
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.8	0.3	0.9	-0.4
Arm fat-free mass (right)	0.2	1.1	3.1	-0.4	-0.4	1.8
Comparative body size at age 10	0.2	0.6	0.9	-0.9	-0.3	1.0
Neck or shoulder pain in last month	0.2	0.3	0.4	0.6	0.6	-0.3
Medication: Allopurinol	0.2	0.3	0.6	0.3	-0.8	0.3
Arm predicted mass (right)	0.2	1.2	3.3	-0.3	-0.3	1.8
Alcohol intake frequency.	0.2	0.4	0.6	0.7	0.8	0.1
Supplements: Vitamin C	0.2	0.3	0.4	0.7	-0.2	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.5	-0.2	0.7	-0.4
Mood swings	0.2	0.3	0.7	0.8	0.0	0.5
Diabetes diagnosed by doctor	0.2	0.3	0.8	-0.1	0.9	0.5
Breast cancer (self-reported)	0.2	0.2	0.4	-0.1	-0.3	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.1	0.4	0.1	-1.1
Mother’s age at death	0.2	0.3	0.8	0.9	0.2	-0.0
Basal metabolic rate	0.2	1.1	2.1	-0.9	-0.8	1.4
Arm fat-free mass (left)	0.2	0.8	2.2	-0.3	-0.4	1.5
Age started oral contraceptive pill	0.2	0.3	0.9	0.1	0.0	1.0
Cholesterol lowering medication	0.2	0.3	0.7	0.1	-0.5	-0.9
Basal cell carcinoma (self-reported)	0.2	0.2	0.3	-0.6	-0.2	0.4
Arm predicted mass (left)	0.2	1.2	3.0	-0.6	-0.5	1.7
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.3	0.2	0.5	0.5
Worry (Nagel 2018)	0.1	0.2	0.4	0.3	-0.6	0.0
Alzheimer’s Disease (in father)	0.1	0.1	0.2	0.4	-0.4	0.3
Bipolar Disorder (2011)	0.1	0.1	0.2	0.5	0.0	-0.2
Neuroticism (2016)	0.1	0.2	0.3	-0.5	0.1	0.5
Ulcerative Colitis	0.1	0.2	0.5	0.3	-0.7	-0.1
Blood Eosinophil Count	0.1	0.8	1.4	-1.2	-0.8	-0.5
Blood Platelet Count	0.1	1.1	3.1	-1.8	-0.4	0.2
Lung FVC	0.1	0.7	1.0	0.7	-0.7	1.0
Ever had hysterectomy (womb removed)	0.1	0.1	0.4	-0.2	0.1	0.6
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.1	-0.2	-0.0	0.4
Medication: Co-codamol	0.1	0.1	0.4	0.6	0.1	0.1
Leg fat-free mass (left)	0.1	0.7	1.0	-0.8	-0.6	1.0
Maternal smoking around birth	0.1	0.1	0.1	0.2	0.4	-0.3
Fed-up feelings	0.1	0.3	0.7	0.8	-0.1	-0.2
Supplements: Glucosamine	0.1	0.1	0.2	-0.0	0.4	0.5
Medication: Atenolol	0.1	0.1	0.1	0.2	-0.2	0.3
Impedance of leg (left)	0.1	0.2	0.5	-0.7	-0.1	0.5
Leg predicted mass (left)	0.1	0.7	0.9	-0.8	-0.6	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.1	-0.4	0.3	-0.1
Diabetes (self-reported)	0.1	0.2	0.5	-0.2	0.7	0.3
Impedance of arm (right)	0.1	0.5	1.0	-1.0	-0.4	-0.6
Trunk fat-free mass	0.1	0.8	2.3	-0.1	-0.1	1.5
Hair/balding pattern: Pattern 3	0.1	0.2	0.4	0.6	-0.0	-0.3
Trunk predicted mass	0.1	0.7	2.1	0.0	0.0	1.4
Tense / ‘highly strung’	0.1	0.2	0.6	0.8	-0.3	-0.1
Gout (self-reported)	0.1	0.1	0.2	0.4	0.2	0.4
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.3	0.5	-0.5	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.4	0.1	0.6	-0.1
Medication: Omeprazole	0.1	0.2	0.4	-0.4	0.2	0.6
Suffer from ‘nerves’	0.1	0.1	0.2	0.4	0.5	-0.2
Family relationship satisfaction	0.1	0.1	0.2	-0.4	0.0	0.4
Whole body fat-free mass	0.1	0.6	1.7	-0.3	-0.3	1.3
Average weekly red wine intake	0.1	0.1	0.2	0.4	0.5	0.2
Long-standing illness, disability or infirmity	0.1	0.1	0.2	-0.1	0.4	0.4
Back pain experienced in last month	0.1	0.1	0.1	-0.4	-0.0	-0.3
Whole body water mass	0.1	0.8	2.1	-0.4	-0.3	1.4
Miserableness	0.1	0.2	0.5	0.1	0.1	0.7
Hearing aid user	0.1	0.1	0.2	0.1	0.4	-0.1
Medication: Blood pressure	0.1	0.2	0.5	0.2	-0.7	-0.3
Irritability	0.1	0.2	0.3	0.4	0.6	0.3
Pain experienced in last month	0.1	0.1	0.2	0.4	-0.3	-0.2
Supplements: Calcium	0.1	0.2	0.4	-0.2	0.6	-0.2
Neuroticism (Nagel 2018)	0.0	0.1	0.3	0.5	0.1	-0.1
Type 2 Diabetes (T2D) (2018)	0.0	0.0	0.1	-0.4	0.0	-0.0
Neuroticism	0.0	0.1	0.3	0.1	-0.0	0.5
Tanning	0.0	0.1	0.1	0.3	-0.1	-0.2
Nervous feelings	0.0	0.0	0.1	0.3	0.2	-0.2
Forced vital capacity (FVC)	0.0	0.1	0.3	0.6	-0.3	0.2
Lung cancer (father)	0.0	0.0	0.0	-0.1	0.2	0.0
Impedance of arm (left)	0.0	0.2	0.3	-0.3	0.4	-0.5
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.1	-0.2	0.3	-0.0
Age at first live birth	0.0	0.1	0.1	-0.1	-0.3	-0.3
Number of full sisters	0.0	0.0	0.0	0.0	0.1	0.1
Leg fat-free mass (right)	0.0	0.1	0.2	-0.2	-0.2	0.5
Leg predicted mass (right)	0.0	0.1	0.2	-0.3	-0.3	0.4
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.1	-0.2	0.1	0.2
Impedance of whole body	0.0	0.1	0.4	-0.6	0.1	-0.0

Hub : Genes

ARHGAP20

Models

Trait associations