Best TWAS P=2e-17 · Best GWAS P=2.66e-16 conditioned to 0.00919
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | ERC1 | 0.08 | 0.05 | enet | 25 | 0.04 | 9.3e-07 | 7.1 | 8.5 | 2.0e-17 | 0.62 | 0.25 | 0.74 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ERC1 | 0.03 | 0.03 | lasso | 3 | 0.03 | 2.2e-07 | 5.8 | 5.8 | 5.4e-09 | 0.08 | 0.99 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ERC1 | 0.10 | 0.02 | blup | 219 | 0.06 | 7.6e-07 | 3.8 | 6.8 | 7.5e-12 | 0.22 | 0.31 | 0.02 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | ERC1 | 0.12 | 0.00 | blup | 218 | 0.05 | 8.9e-05 | 3.9 | 7.0 | 2.3e-12 | 0.45 | 0.02 | 0.45 | TRUE |