Hub : Genes

ERC1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0960 0.0310 9.8e-06 0.025 0.036 0.055 0.046 0.055 4.9e-04 3.1e-05 3.0e-07 2.6e-06 3.0e-07
2 GTEx Colon Sigmoid 0.2070 0.0880 8.6e-03 -0.007 NA -0.008 NA -0.003 6.6e-01 NA 9.1e-01 NA 4.2e-01
3 GTEx Testis 0.3150 0.0800 3.5e-04 0.045 NA 0.113 NA 0.183 4.6e-03 NA 1.0e-05 NA 1.5e-08
4 METSIM Adipose 0.0776 0.0230 7.8e-05 0.045 0.034 0.040 0.036 0.037 2.1e-07 7.1e-06 9.3e-07 3.4e-06 3.0e-06
5 TCGA Breast Invasive Carcinoma 0.0313 0.0139 3.8e-03 0.034 0.017 0.029 NA 0.033 1.6e-07 1.8e-04 1.2e-06 NA 2.2e-07
6 TCGA Kidney Renal Clear Cell Carcinoma 0.1034 0.0323 2.8e-05 0.016 0.055 0.028 NA 0.019 5.7e-03 7.6e-07 3.7e-04 NA 2.8e-03
7 TCGA Brain Lower Grade Glioma 0.0863 0.0367 5.0e-05 0.031 0.044 0.029 NA 0.030 1.7e-04 9.0e-06 2.4e-04 NA 2.2e-04
8 TCGA Stomach Adenocarcinoma 0.1210 0.0490 2.7e-03 0.000 0.054 0.033 NA 0.015 3.5e-01 8.9e-05 1.9e-03 NA 2.9e-02
9 TCGA Thyroid Carcinoma 0.0710 0.0420 2.5e-03 0.018 0.030 0.028 NA 0.036 6.2e-03 6.5e-04 8.2e-04 NA 1.7e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.5 0.9 2.0 -1.4 -1.1 -0.4 0.8 0.5 0.3 -0.8 -1.1 -1.3
Bipolar Disorder or Schizophrenia 0.5 1.3 3.3 -1.8 -0.2 0.4 1.8 1.2 1.1 -1.4 0.0 0.1
Depressed Affect (Nagel 2018) 0.4 0.8 2.7 0.6 -0.3 -0.1 -0.5 -1.6 -1.6 0.5 -1.0 -0.7
Depression (Nagel 2018) 0.9 1.4 5.9 -0.5 -1.5 -0.3 1.2 0.3 -1.4 -0.7 -0.3 -2.4
Intelligence (Savage-Jansen 2018) 0.7 2.3 6.2 2.5 2.1 1.6 0.1 -1.4 0.7 1.8 1.1 0.7
Neuroticism (Nagel 2018) 0.1 0.3 0.9 0.2 -1.0 -0.1 0.9 -0.2 -0.5 -0.0 -0.6 -0.4
Schizophrenia (2018) 0.6 1.3 2.7 -1.2 0.9 0.9 1.6 1.2 1.1 -1.2 1.0 1.2
Schizophrenia vs Biploar Disorder 0.1 0.2 0.8 0.1 -0.1 0.3 0.4 -0.3 0.0 -0.6 -0.1 0.9
Worry (Nagel 2018) 1.1 2.2 5.4 -1.1 -2.0 -1.2 2.3 2.3 0.8 -1.0 0.2 -1.0
Alzheimer’s Disease (in mother) 0.7 0.9 3.5 0.4 0.4 1.5 -0.3 -1.1 -0.1 0.2 1.9 0.3
Alzheimer’s Disease (in father) 0.7 0.7 1.8 -0.7 0.4 1.3 0.8 0.1 1.1 -0.5 1.2 0.8
Alzheimer’s Disease (including proxy) 1.5 2.2 8.9 0.4 1.2 3.0 -0.4 -1.5 0.4 0.4 2.3 1.0
Crohns Disease (2017) 0.8 1.8 8.4 -1.5 -0.1 1.1 2.9 0.4 1.1 0.1 1.8 0.1
Irritable Bowel Disease (IBD) 0.9 2.2 6.6 -1.9 -0.4 0.3 2.6 1.5 2.0 -0.1 1.7 -0.4
Ulcerative Colitis (UC) 0.6 1.1 3.5 -1.2 -0.5 -0.8 1.0 1.6 1.9 -0.0 0.5 -0.6
Major Depression (MDD) 1.2 1.4 5.0 -2.1 -0.0 0.6 0.7 0.4 -1.2 -2.2 -0.6 -1.0
Reaction Time 0.4 0.7 2.0 -1.4 -0.0 -0.5 0.8 1.1 1.4 -0.4 0.5 0.1
Verbal and Numeric Reasoning (VNR) 0.8 1.9 5.8 2.4 1.7 1.9 -0.7 -1.8 -0.4 1.1 0.0 0.4
Breast Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Ovarian Cancer 0.2 0.2 0.5 0.5 0.4 -0.5 -0.2 0.0 -0.7 0.6 -0.4 -0.3
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.4 0.6 2.3 0.7 0.7 0.5 -0.2 -0.3 -0.1 1.3 0.4 1.5
Bipolar Disorder (2011) 0.9 0.8 2.8 -1.7 0.1 -0.2 0.5 1.5 0.4 -1.0 0.9 -0.5
Body Mass Index (BMI) (2010) 0.4 0.5 1.4 0.7 0.1 0.7 -1.2 -1.1 -0.1 0.6 -0.6 0.2
Coronary Artery Disease (CAD) 0.5 0.6 2.0 -0.7 -1.4 -1.0 0.9 0.6 -0.6 -0.7 -0.2 0.0
Crohns Disease (2012) 1.1 1.8 7.5 -1.0 0.3 1.7 2.7 0.3 1.1 0.1 1.4 1.1
Mean Putamen Volume 0.2 0.2 0.5 -0.5 0.2 -0.5 0.7 0.2 0.7 0.2 0.0 0.6
Fasting Glucose 0.4 0.5 1.5 1.1 -0.5 -0.6 0.0 -1.2 -0.4 0.6 -0.8 0.1
HbA1C 1.0 1.1 6.8 0.4 0.1 1.2 0.9 0.7 0.2 -0.5 2.6 -0.1
HDL Cholesterol 0.5 0.9 2.4 -1.3 -0.6 0.0 1.0 1.6 0.9 -0.8 1.1 -0.4
LDL Cholesterol 0.9 1.4 4.5 -0.9 -1.0 0.4 0.0 0.9 -1.6 -2.1 -0.1 -1.8
Lupus 0.3 0.4 0.8 -0.6 0.9 0.7 0.1 -0.6 0.9 -0.6 -0.5 -0.3
Neuroticism (2016) 0.7 1.0 5.3 1.3 -0.7 0.2 0.8 0.0 -0.6 -0.6 0.4 -2.3
Primary Biliary Cirrhosis 0.4 0.6 1.1 -0.4 0.8 1.0 1.1 0.0 0.9 0.7 0.9 0.8
Rheumatoid Arthritis 1.8 2.4 4.8 1.9 2.2 1.5 0.1 -1.7 0.9 1.8 0.7 2.0
Schizophrenia (2014) 0.5 1.1 1.8 -1.4 0.4 1.2 1.1 1.3 1.0 -1.1 0.6 1.0
Triglycerides 0.9 1.4 6.9 -0.7 -1.4 -0.2 0.1 0.1 -2.6 -0.8 -1.6 -0.6
Type 2 Diabetes (T2D) (2012) 0.5 0.6 2.5 0.5 0.1 -0.2 -0.6 0.0 1.4 1.6 0.2 -0.3
Ulcerative Colitis 0.2 0.3 1.1 -0.6 0.0 -0.4 0.1 -0.0 0.9 -0.1 0.4 -1.1
Blood Eosinophil Count 0.2 1.9 4.2 2.0 1.7 0.3 -1.4 -0.3 1.2 1.8 1.3 1.4
Blood Platelet Count 0.4 4.1 8.4 2.7 2.9 1.6 -1.6 -2.2 0.9 2.4 2.3 0.1
Blood Red Count 0.1 0.7 3.3 -0.9 -0.1 -0.7 0.3 0.5 1.0 0.1 -0.5 1.8
Blood White Count 0.6 4.4 10.2 1.9 3.0 0.6 0.9 -0.3 3.0 2.0 3.2 1.4
Heel T-Score 1.1 9.1 35.8 -3.4 -3.1 -6.0 -0.1 3.4 -3.6 -1.0 -0.6 -0.6
BMI 0.6 3.3 12.7 1.4 1.2 1.1 -0.3 -1.9 2.1 1.9 -0.9 3.6
Height 1.2 23.8 77.3 -2.3 -2.2 -0.0 -6.6 -2.8 -8.8 -3.5 -6.9 -4.1
Waist Hip Ratio (WHR) 1.9 8.5 22.2 2.7 1.8 3.2 -3.7 -4.7 -2.4 3.7 0.1 -0.0
Systolic Blood Pressure 0.7 3.5 7.2 -1.3 -1.5 -1.3 2.3 2.7 2.0 -2.0 2.1 -0.8
Smoking Status 0.3 0.8 2.3 -1.0 -0.6 -1.1 1.5 1.5 0.5 -0.2 -0.3 0.1
Allergy or Eczema 0.9 2.3 5.7 1.9 0.4 2.0 -0.3 0.2 2.3 1.3 2.4 0.1
Cardiovascular Disease 1.1 3.7 9.3 -1.5 -2.2 -1.8 3.0 2.6 1.2 -2.2 0.1 -0.6
Hypothyroidism (self reported) 0.5 1.1 3.4 -1.9 -0.6 -1.2 1.0 1.5 0.3 -1.1 0.2 -0.3
Respiratory disease 0.1 0.2 0.6 0.0 0.3 -0.2 -0.6 0.2 -0.2 0.2 0.5 0.8
Type 2 Diabetes (T2D) (2018) 3.1 5.9 15.2 2.8 3.9 2.1 -1.9 -2.6 1.7 2.5 1.1 2.1
Lung FEV1/FVC ratio 4.6 23.4 72.1 -1.2 0.0 -2.4 8.5 5.8 6.8 -0.9 7.0 -0.7
Lung FVC 3.3 16.7 37.8 4.5 3.8 3.7 -6.2 -4.6 -2.2 4.1 -2.9 3.7
Neuroticism 0.1 0.3 0.9 0.2 -0.8 -0.2 0.9 0.1 0.1 0.0 -0.4 -1.0
Chronotype (morning person) 0.3 0.8 2.2 0.4 1.3 -0.2 -0.2 -0.4 1.4 0.8 -0.3 1.5
Hair Pigment 0.0 1.2 3.1 1.0 -0.0 1.0 -1.7 -1.8 -0.9 -0.1 1.0 -1.0
Tanning 0.1 1.5 3.7 1.2 1.7 0.8 1.0 0.4 1.7 0.7 0.9 1.9
Hand grip strength (left) 0.2 0.6 2.2 -0.4 -0.4 0.6 -1.5 0.2 -1.1 -1.1 -0.4 0.3
Number of treatments/medications taken 0.2 0.4 1.0 -0.9 -0.1 -0.9 0.1 -0.2 -1.0 0.6 -0.3 0.2
Average weekly spirits intake 0.6 0.8 3.2 -0.7 -0.2 -0.8 0.8 1.2 -0.8 -0.2 0.1 1.8
Sensitivity / hurt feelings 0.6 1.0 2.8 1.5 1.0 0.4 0.5 -0.5 0.9 0.9 -0.6 1.7
Frequency of depressed mood in last 2 weeks 1.2 1.7 4.8 -0.7 -1.9 -0.6 0.7 0.9 -1.5 -0.5 -1.6 -2.2
Hearing difficulty/problems: Yes 0.7 1.0 4.8 0.5 0.1 -1.1 -0.6 -0.9 -1.1 0.3 -2.2 0.5
Relative age of first facial hair 1.0 2.1 7.2 -0.3 2.1 1.4 1.1 -0.4 1.2 0.9 2.7 -1.2
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 5.8 -0.5 0.9 0.2 0.1 0.3 -0.2 0.9 -0.2 2.4
Ever used hormone-replacement therapy (HRT) 0.5 0.7 1.3 0.7 0.0 -1.1 -0.1 -1.1 -0.7 0.6 -1.1 1.1
Ever had hysterectomy (womb removed) 0.8 1.0 3.3 -0.8 -0.3 -1.1 0.1 0.1 0.6 1.8 -0.7 1.5
Systolic blood pressure, automated reading 0.5 1.6 4.9 -1.3 -0.8 -1.0 1.4 1.2 1.3 -2.2 0.7 -0.0
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 2.0 0.4 0.2 1.0 -0.2 -0.5 0.2 1.4 -0.0 -0.1
Angina 1.0 1.3 6.0 0.4 0.7 0.7 0.8 -0.1 1.2 1.2 1.0 2.4
Medication for hormone replacement therapy 0.4 0.5 1.4 -0.4 -1.2 -0.9 -0.4 0.2 -0.4 0.2 -1.0 -0.4
Vitamin and mineral supplements 0.5 0.7 3.5 0.3 1.0 0.8 0.5 -0.6 0.3 0.5 0.2 1.9
Supplements: Zinc 0.4 0.4 1.3 -0.1 -0.2 -0.2 -0.9 0.8 -0.4 0.6 -0.5 -1.1
Medication: Co-codamol 0.4 0.5 2.3 -0.3 -0.2 -1.5 0.2 1.0 -0.0 0.4 -0.6 -0.3
Medication: Metformin 3.0 4.2 10.6 2.4 2.4 3.3 -1.5 -2.6 0.6 2.6 0.5 0.4
Diabetes (father) 1.0 1.2 3.2 0.8 0.2 0.6 -1.6 -1.6 -0.8 1.8 -0.3 0.9
Diabetes (mother) 0.3 0.3 0.9 -0.4 0.1 1.0 -0.2 -0.8 -0.2 0.7 -0.3 0.7
Severe depression (siblings) 0.4 0.4 1.0 0.1 0.6 0.8 0.0 -1.0 -0.0 0.8 0.7 0.8
Pack years adult smoking proportion 0.9 1.4 4.2 0.8 0.4 0.6 -1.1 -1.0 -1.2 1.9 -2.0 0.8
Impedance of leg (right) 1.1 5.5 12.9 -2.6 -3.4 -1.0 0.0 0.3 -3.2 -2.0 -1.5 -3.6
Leg fat-free mass (left) 0.6 3.4 10.2 0.9 1.3 1.4 -3.2 -2.7 -1.8 0.2 -2.0 1.2
Trunk fat percentage 1.0 4.0 12.2 -0.1 0.1 1.3 -2.2 -3.5 -2.2 0.6 -3.5 0.4
Hand grip strength (right) 0.4 1.2 4.4 -0.7 -1.2 0.1 -0.9 0.1 -1.6 -2.1 -0.9 -0.6
Townsend deprivation index at recruitment 0.5 0.7 3.1 -1.2 -0.6 0.6 -0.0 0.7 0.1 -0.7 -0.2 -1.8
Current tobacco smoking 0.8 1.3 3.8 -0.6 0.0 -1.5 1.9 2.0 0.7 -0.1 0.2 0.8
Average weekly fortified wine intake 0.3 0.4 1.5 -0.2 0.2 0.8 0.5 -0.2 0.8 1.2 0.1 0.6
Maternal smoking around birth 2.3 3.4 11.3 -0.5 0.4 0.2 -2.4 -2.7 -3.4 -0.3 -2.4 0.1
Fed-up feelings 0.4 0.8 2.4 0.3 -0.5 -0.0 0.3 -1.5 -1.1 0.6 -1.5 0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 2.5 3.3 8.1 -1.8 -2.2 -1.1 1.6 0.6 -2.2 -2.0 -0.6 -2.9
Relative age voice broke 1.0 1.5 5.5 -1.0 1.3 0.3 1.3 0.4 0.9 -0.1 2.3 -1.5
Taking other prescription medications 0.6 0.9 4.3 -1.3 -1.1 0.4 -0.4 0.0 -2.1 0.3 -0.4 -0.2
Age when periods started (menarche) 0.6 1.4 4.1 0.3 -0.5 2.0 -0.7 -1.3 -1.6 -0.3 -0.2 -1.6
Bilateral oophorectomy (both ovaries removed) 1.2 1.4 6.3 -0.1 -0.5 0.1 -1.7 -0.2 -1.6 -0.1 -2.5 0.9
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 1.8 -0.8 -1.1 -1.0 0.3 1.3 -0.6 -0.2 0.8 -0.6
Tinnitus: Yes, but not now, but have in the past 0.2 0.3 0.9 -0.5 0.1 -0.7 0.0 0.8 -0.1 -1.0 0.3 -0.2
Qualifications: CSEs or equivalent 1.1 1.5 5.6 -0.8 -0.8 -1.0 -1.1 0.3 -1.5 -1.2 -0.4 -2.4
Serious illness, injury or assault to yourself 0.3 0.3 1.0 -0.2 -0.2 -0.8 1.0 0.5 -0.4 0.4 -0.3 0.6
High blood pressure 0.9 2.6 5.9 -1.5 -1.4 -1.2 2.2 2.2 0.5 -2.4 -0.4 -1.6
Hayfever, allergic rhinitis or eczema 1.0 2.2 6.1 1.9 0.5 2.4 -0.3 -0.3 1.5 1.4 2.5 0.2
Multivitamins +/- minerals 0.7 0.9 4.5 0.5 0.1 0.1 -1.4 -0.7 0.4 0.7 0.0 -2.1
Stomach or abdominal pain in last month 1.4 1.7 5.2 2.3 1.2 -0.5 -0.5 -0.7 -0.9 2.2 0.6 1.3
Supplements: Glucosamine 0.4 0.6 1.6 -1.1 -0.1 0.7 0.8 0.4 -1.3 -0.8 -0.1 -0.4
Diverticular disease/diverticulitis (self-reported) 0.9 1.1 2.8 -0.1 1.7 1.4 0.7 0.1 1.4 0.7 0.3 1.4
Medication: Atenolol 0.6 0.7 2.2 0.7 -0.2 0.8 0.6 -0.7 0.9 0.8 1.5 0.7
Medication: Levothyroxine sodium 0.8 1.3 3.1 -1.8 -1.2 -1.2 0.5 1.2 -0.6 -1.4 -1.2 0.4
Sitting height 1.3 9.3 32.8 0.1 -0.9 1.3 -4.6 -2.5 -5.7 -1.6 -4.1 -1.2
Chronic bronchitis/emphysema (father) 2.2 2.6 7.3 -0.5 -1.9 0.1 -1.8 -1.9 -2.7 -0.5 -1.9 -1.2
High blood pressure (mother) 0.2 0.3 1.7 -0.1 0.2 0.1 0.5 -0.1 -0.4 0.2 0.9 1.3
Body mass index (BMI) 0.5 2.0 6.1 1.0 1.2 1.0 -0.6 -2.0 0.5 1.3 -1.6 2.5
Impedance of leg (left) 0.8 3.8 13.0 -2.0 -2.8 -1.0 0.3 0.2 -2.5 -1.2 -1.0 -3.6
Leg predicted mass (left) 0.6 3.4 9.9 0.9 1.3 1.4 -3.2 -2.6 -1.8 0.1 -2.0 1.2
Trunk fat mass 1.1 4.9 14.8 -0.1 0.0 1.5 -2.7 -3.5 -2.7 0.3 -3.9 0.5
Waist circumference 1.1 4.2 13.5 1.5 1.2 2.1 -2.0 -3.7 -1.2 1.9 -1.8 1.8
Number of incorrect matches in round 0.4 0.6 2.0 -0.9 0.3 -0.0 1.4 0.6 1.2 0.1 0.9 0.6
Past tobacco smoking 0.6 1.2 3.8 0.6 -0.5 -0.9 -1.9 -1.0 -1.6 -0.4 -1.2 -0.3
Alcohol usually taken with meals 0.6 1.0 3.3 1.8 1.0 0.6 -0.1 -0.5 0.9 0.6 1.6 0.7
Nervous feelings 1.7 3.1 7.7 -1.4 -2.3 -1.4 2.8 2.2 1.5 -0.7 1.4 -1.3
Frequency of tenseness / restlessness in last 2 weeks 0.7 1.1 3.0 -0.5 -1.2 -1.1 1.5 1.7 -0.3 -0.2 -1.1 -0.5
Hearing difficulty/problems with background noise 0.5 0.9 1.6 -1.2 -1.1 -1.2 1.3 1.0 0.8 -0.8 -0.3 0.1
Hair/balding pattern: Pattern 2 3.2 4.0 7.4 2.4 2.5 1.7 -1.6 -2.7 -1.8 2.6 1.1 0.6
Had menopause 0.2 0.3 0.9 0.1 0.1 -0.7 0.6 -0.3 1.0 0.1 -0.2 0.7
Had other major operations 0.6 0.8 2.8 -1.7 0.4 0.4 0.9 1.0 0.0 0.1 0.6 1.3
Forced vital capacity (FVC) 2.2 8.3 31.2 1.9 1.9 2.6 -5.6 -3.1 -3.0 1.2 -2.6 1.2
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.6 2.1 -0.5 -1.2 -0.8 -0.5 0.4 -1.4 -0.6 0.4 -0.5
Ever unenthusiastic/disinterested for a whole week 1.1 1.4 3.5 -1.7 -0.1 -1.3 1.2 1.5 0.1 -1.9 -0.3 0.5
Qualifications: None of the above 2.3 4.9 14.6 -2.2 -1.9 -3.8 -0.2 1.0 -0.7 -1.1 -2.8 -3.2
Financial difficulties in last 2 years 0.6 0.8 2.0 1.3 1.3 1.4 -0.7 -0.1 0.1 -0.1 1.2 0.2
Mouth/teeth dental problems 0.6 0.8 2.8 -1.2 -0.0 -0.1 0.1 1.7 0.7 -1.5 0.4 -0.6
Heart attack 0.6 0.8 3.0 0.8 -0.1 -0.7 0.4 -0.5 -1.0 0.5 -1.7 1.1
Allergy 0.5 1.1 3.1 -1.2 -0.3 -1.3 0.4 -0.1 -1.0 -1.3 -1.8 -0.5
Pain all over the body in last month 0.4 0.4 1.1 -1.1 -0.5 -0.8 0.2 0.6 -0.2 -0.9 0.4 -0.4
Diabetes (self-reported) 2.6 4.1 7.5 2.7 2.4 1.5 -2.5 -2.4 0.3 2.7 -0.5 1.2
Hayfever/allergic rhinitis (self-reported) 0.8 1.1 3.3 1.2 0.8 1.5 -0.7 -0.3 1.8 0.9 0.9 -0.4
Medication: Ramipril 0.6 0.8 1.5 -1.1 0.1 -1.2 1.1 1.1 0.5 0.1 -1.1 -0.0
Medication: Simvastatin 0.1 0.1 0.4 0.3 -0.0 0.4 0.6 0.1 -0.1 -0.3 -0.4 0.1
Fluid intelligence score 0.3 0.6 1.8 1.3 -0.0 1.4 -0.3 -1.1 -0.6 0.2 -0.2 -0.0
Illnesses of siblings 0.9 1.3 3.1 -0.9 -0.8 -0.9 1.5 1.5 -0.1 -1.1 1.8 -0.7
Neuroticism score 0.1 0.2 1.0 -0.0 -0.4 -0.1 0.8 -0.2 0.2 -0.1 -0.4 -1.0
Weight 0.9 4.4 11.1 0.5 0.6 1.3 -2.9 -3.3 -2.4 0.2 -3.3 1.2
Impedance of arm (right) 0.5 2.5 8.3 -1.0 -1.1 0.9 -1.9 -1.1 -2.9 -1.0 -0.7 -2.3
Arm fat percentage (right) 0.5 1.8 5.3 0.1 0.5 1.3 -1.1 -2.3 -0.7 0.6 -2.3 1.4
Trunk fat-free mass 0.4 2.4 7.0 0.2 -0.1 0.3 -2.6 -1.5 -2.7 -0.8 -2.1 0.2
Hip circumference 0.2 0.8 3.7 -0.4 -0.1 0.6 -0.1 -1.1 -0.2 -0.7 -1.9 1.3
Time employed in main current job 1.0 1.1 3.7 0.3 0.9 0.5 -1.8 -0.8 0.5 1.9 0.5 -0.9
Alcohol intake versus 10 years previously 1.5 2.2 5.8 -2.4 -1.5 -0.9 -1.2 2.1 -1.1 -0.4 -0.9 -1.8
Father’s age at death 2.0 2.7 8.0 0.8 1.1 -0.4 2.4 0.1 2.2 0.9 2.8 1.6
Worrier / anxious feelings 0.7 1.4 3.1 -0.4 -1.6 -1.4 1.3 1.8 0.1 -1.0 -1.1 -0.8
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 3.4 0.0 0.1 0.9 -0.9 -1.2 -1.8 0.5 -1.3 -0.1
Falls in the last year 1.3 1.7 8.9 0.4 1.9 -0.1 1.1 -0.9 0.1 0.3 0.9 3.0
Hair/balding pattern: Pattern 3 0.8 1.3 6.3 -0.1 0.8 -0.5 1.2 1.4 2.5 -0.1 0.7 0.6
Number of live births 0.9 1.3 2.4 -1.5 -1.3 -1.5 0.7 1.4 0.9 -0.8 -1.1 -0.2
Forced expiratory volume in 1-second (FEV1) 1.1 3.6 10.2 1.9 2.3 2.1 -3.2 -1.7 -0.7 1.6 -0.4 1.5
Pulse rate 1.1 1.9 4.3 -0.5 -1.4 -1.7 0.6 0.8 -1.9 -2.1 -1.9 -0.3
Happiness 0.3 0.4 1.1 -0.4 0.4 -0.3 1.0 1.0 -0.3 -0.5 0.4 0.7
Noisy workplace 0.3 0.4 2.1 0.6 -0.4 -1.5 0.1 -0.4 -0.4 0.2 -0.3 -0.4
Qualifications: A levels/AS levels or equivalent 1.3 2.9 6.1 2.0 0.4 2.0 0.9 0.5 2.5 0.0 2.2 2.4
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.3 0.9 0.1 0.6 0.6 -0.2 -0.2 -0.5 0.9 0.3 0.5
Mouth/teeth dental problems: Dentures 1.4 2.4 6.2 1.8 -0.1 0.5 -1.3 -2.3 -0.7 2.5 -0.4 2.0
Asthma 0.3 0.6 1.7 -0.9 -0.5 -1.3 -0.5 0.8 -0.7 -0.8 -0.3 0.1
Medication: Ibuprofen (e.g. Nurofen) 1.0 1.2 4.0 0.7 0.5 0.4 -1.3 -1.9 -2.0 0.4 -0.7 0.6
Medication: Cholesterol lowering 0.7 1.1 2.6 1.6 0.9 0.1 1.5 -0.6 0.9 1.3 -0.0 1.2
Depression (self-reported) 1.0 1.2 5.4 -0.7 0.9 1.4 0.6 0.4 0.8 -0.7 2.3 -0.9
Medication: Lansoprazole 0.6 0.7 1.6 -1.1 -0.7 -0.0 0.5 0.7 -0.8 -1.3 -1.2 0.1
Prospective memory result 0.3 0.4 1.0 -0.4 0.5 0.5 -0.2 -0.4 0.4 0.8 -0.7 1.0
Lung cancer (father) 1.1 1.3 3.5 0.7 0.6 1.6 -1.9 -1.6 -0.6 0.1 -1.3 -0.6
Illnesses of mother 0.8 1.0 3.9 -1.1 -1.0 -0.2 -0.2 0.4 0.1 -0.6 -1.5 -2.0
Forced expiratory volume in 1-second (FEV1), Best measure 1.3 4.1 8.2 2.4 2.6 2.2 -2.9 -2.0 -0.0 1.8 -0.0 1.9
Pulse wave Arterial Stiffness index 1.5 1.7 6.4 -1.8 -0.0 -0.9 0.3 1.1 -0.5 -1.1 -1.6 -2.5
Impedance of arm (left) 0.5 2.4 6.0 -1.1 -1.0 0.7 -1.8 -1.5 -2.4 -1.2 -0.7 -2.4
Arm fat mass (right) 0.7 2.7 7.6 0.4 0.6 1.3 -1.8 -2.7 -1.3 0.5 -2.7 1.4
Trunk predicted mass 0.4 2.3 7.1 0.3 -0.0 0.3 -2.6 -1.5 -2.7 -0.8 -2.1 0.2
Standing height 1.3 13.1 44.5 -1.0 -1.5 0.8 -5.4 -3.2 -6.7 -2.5 -4.1 -2.6
Length of working week for main job 0.7 0.7 2.3 0.8 1.1 1.5 -0.4 -0.4 0.7 0.3 0.8 1.0
Exposure to tobacco smoke at home 1.0 1.1 2.3 -0.7 -0.6 -1.5 1.1 1.4 0.0 -1.1 0.8 -1.3
Breastfed as a baby 0.8 0.9 3.6 0.6 0.8 0.7 1.2 0.1 1.9 0.2 1.4 0.2
Tense / ‘highly strung’ 1.9 3.1 8.9 -0.6 -1.2 -1.2 3.0 2.8 2.4 -0.3 1.3 0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 1.2 1.8 4.2 -2.0 -0.8 -1.1 1.3 1.9 1.0 -2.0 0.2 -0.6
Hair/balding pattern: Pattern 4 0.3 0.7 1.7 -1.3 -1.1 -0.9 -0.6 -0.3 -0.2 -0.9 -1.2 -0.1
Birth weight of first child 0.3 0.5 1.7 0.6 -0.7 -1.3 0.5 0.0 -0.6 -0.0 -0.4 -1.2
Peak expiratory flow (PEF) 0.5 1.2 2.9 1.7 1.4 0.9 -1.4 -0.4 -0.3 1.1 0.9 1.0
Pulse wave reflection index 0.4 0.5 1.4 -0.4 0.7 -0.2 -0.9 0.1 0.1 1.1 -1.2 0.4
Ever highly irritable/argumentative for 2 days 1.2 1.4 5.0 -2.2 -0.2 -0.9 0.9 1.6 -0.3 -1.3 0.5 1.1
Loud music exposure frequency 0.7 0.7 2.1 0.7 0.4 1.0 1.4 -0.2 1.1 -0.1 1.0 0.9
Qualifications: O levels/GCSEs or equivalent 0.7 1.1 3.1 0.1 -0.4 1.5 0.4 1.2 1.0 0.2 1.8 1.3
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 1.6 1.3 1.1 0.5 -0.2 -0.6 -1.1 0.3 -0.2 -0.9
Blood clot in the leg (DVT) 1.3 1.6 4.9 1.3 2.2 1.0 -0.3 -0.8 1.3 1.0 1.7 1.0
Medication: Paracetamol 0.5 0.9 4.5 0.5 0.1 0.5 -0.7 -2.1 -1.1 0.6 -0.2 0.7
Headache pain in last month 1.5 2.5 8.6 1.5 0.7 1.1 -2.9 -2.4 -1.1 1.4 -0.6 -0.9
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 1.0 -1.0 -0.1 0.3 -0.8 0.4 0.4 -0.4 0.5 -0.1
Glaucoma (self-reported) 0.9 1.1 2.7 -1.6 -0.9 -0.8 0.6 1.3 0.2 -0.6 0.5 -1.6
Gout (self-reported) 0.5 0.7 3.3 -0.5 -0.5 -0.3 0.2 1.0 -1.1 0.3 -1.8 0.3
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 4.3 -2.1 -0.6 -0.6 1.1 1.1 0.5 -1.7 0.3 0.0
Medication: Amlodipine 0.4 0.6 1.7 0.7 -0.2 -1.3 -0.7 -0.4 -1.1 0.4 -0.8 -0.4
Medication: Ventolin 100micrograms inhaler 0.2 0.3 1.3 0.3 -0.1 -0.8 -0.5 0.2 -0.3 1.1 -0.4 0.1
Birth weight 0.9 1.9 4.9 -0.8 -0.5 -0.4 -0.5 -1.3 -2.1 -1.9 -0.9 -2.2
Chronic bronchitis/emphysema (mother) 0.8 1.0 5.3 0.7 1.0 1.0 -2.3 0.1 -0.6 0.7 -0.0 -0.3
High blood pressure (siblings) 0.4 0.6 2.6 0.9 -0.5 0.8 -0.4 -1.6 -0.4 0.7 -0.5 -0.1
Forced vital capacity (FVC), Best measure 2.0 7.5 25.0 2.5 2.4 2.8 -5.0 -3.4 -1.9 1.5 -1.5 1.8
Body fat percentage 0.8 3.1 10.1 0.0 0.1 1.1 -1.8 -3.1 -1.7 0.9 -3.2 0.7
Leg fat percentage (right) 0.4 1.3 6.4 -0.2 -0.4 0.6 -0.5 -1.6 -0.7 0.9 -2.5 0.7
Arm fat-free mass (right) 0.4 2.0 5.0 0.3 0.4 0.2 -2.2 -2.1 -2.0 -0.0 -2.1 0.6
Exposure to tobacco smoke outside home 2.6 3.4 7.7 -0.7 -1.6 -2.1 -1.6 0.3 -2.8 -1.0 -2.7 -2.2
Comparative body size at age 10 0.4 1.2 6.2 0.6 0.4 -0.1 0.5 -0.0 1.5 0.7 -1.1 2.5
Number of full brothers 0.8 0.9 3.5 -1.9 -0.5 -1.4 -0.2 0.5 -1.0 -0.4 0.4 -1.1
Worry too long after embarrassment 0.4 0.7 3.4 -0.8 -0.9 -0.7 0.8 -0.4 0.1 -0.2 -0.2 -1.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 1.1 -0.7 -0.1 0.8 -0.3 0.1 0.3 -1.1 0.6 0.2
Wheeze or whistling in the chest in last year 0.2 0.4 0.8 0.9 -0.4 0.2 0.0 -0.7 -0.7 0.8 -0.3 0.8
Number of children fathered 0.3 0.4 1.1 -0.6 -0.1 -0.4 0.4 1.1 0.0 0.3 -0.9 0.8
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.6 2.3 0.4 0.2 -0.3 0.2 0.0 1.5 0.5 -0.0 1.5
Age at first live birth 0.4 0.6 2.7 1.6 -0.0 0.5 0.0 0.3 -0.1 1.0 -0.3 1.2
Pulse wave peak to peak time 1.3 1.5 4.7 1.8 0.1 1.1 -0.6 -1.4 0.0 1.0 1.3 2.2
Health satisfaction 0.8 1.0 2.7 -1.1 -0.6 -0.5 1.6 1.6 0.3 -0.6 -0.3 1.3
Shortness of breath walking on level ground 0.6 0.7 3.0 -0.6 -0.1 0.6 0.9 0.8 1.7 -0.3 0.7 0.6
Qualifications: College or University degree 0.9 2.8 7.4 2.5 1.2 0.7 1.9 -0.2 1.7 -0.0 1.9 2.7
Eye problems/disorders: None of the above 3.0 3.5 8.8 -3.0 -2.1 -1.7 0.5 1.6 -1.5 -2.6 -1.5 -1.0
Mouth/teeth dental problems: Loose teeth 0.8 1.0 2.7 -0.0 0.5 -0.1 -1.3 -1.6 -1.5 0.8 -0.7 0.8
Emphysema/chronic bronchitis 0.5 0.5 1.9 -0.1 -1.3 0.5 -0.9 0.2 -1.4 0.1 -0.4 -0.3
Medication for pain relief, constipation, heartburn 1.1 1.9 5.3 -1.2 -0.4 -0.9 1.4 2.3 2.1 -1.1 1.2 -0.8
Neck or shoulder pain in last month 0.6 0.8 4.4 -0.3 -0.9 -2.1 -0.1 0.2 -0.6 -0.8 -1.0 -0.0
Medication: Blood pressure 0.4 0.6 3.1 -0.1 -0.2 -1.0 1.8 0.9 0.5 -0.3 0.3 -0.3
Angina (self-reported) 0.7 0.9 4.3 0.1 0.5 0.3 0.8 0.2 0.9 1.0 0.9 2.1
Migraine (self-reported) 1.2 1.5 3.3 -1.5 -0.8 -1.1 -1.1 0.4 -1.8 -1.5 -1.5 -0.9
Medication: Ibuprofen 1.0 1.2 4.0 0.7 0.4 -0.0 -1.3 -1.7 -2.0 0.5 -0.9 0.7
Medication: Allopurinol 0.7 0.9 2.5 -1.2 -0.9 -0.6 0.7 0.8 -1.1 -0.1 -1.6 -0.8
Medication: Omeprazole 0.6 0.7 3.3 -0.6 0.0 0.5 0.7 -0.9 -0.9 -0.2 0.1 1.8
Medication: Seretide 50 evohaler 0.6 0.7 2.6 -0.0 -0.5 -0.2 -1.6 -0.9 -1.5 -0.2 -0.4 0.4
Mean time to correctly identify matches 0.1 0.3 0.7 -0.8 -0.1 -0.5 0.5 0.5 0.8 -0.6 -0.1 -0.2
Heart disease (mother) 0.6 0.7 2.1 1.4 1.1 0.0 -0.2 -1.1 0.8 0.9 0.5 0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.3 1.5 2.6 -1.4 -1.1 -1.1 1.6 1.6 -0.4 -1.2 -0.4 1.4
Whole body fat mass 1.0 4.3 13.8 0.2 0.1 1.2 -2.6 -3.3 -2.2 0.7 -3.7 0.8
Leg fat mass (right) 0.6 2.3 8.3 0.1 0.0 0.8 -1.8 -2.5 -1.2 0.7 -2.9 0.9
Arm predicted mass (right) 0.4 2.1 5.2 0.3 0.3 0.3 -2.3 -2.0 -2.1 -0.1 -2.1 0.5
Pulse rate, automated reading 0.3 0.9 5.5 0.6 -0.6 -0.2 -0.7 -1.0 -2.3 0.1 -0.5 -0.4
Alcohol intake frequency. 0.7 1.7 7.1 -0.7 -1.4 -0.9 -2.7 0.1 -1.2 0.7 -1.3 -1.2
Comparative height size at age 10 1.3 7.3 15.8 -2.9 -2.5 -0.6 -2.9 -0.6 -4.0 -3.0 -3.2 -2.8
Number of full sisters 0.6 0.7 1.6 1.2 0.9 -1.2 -1.0 -0.3 0.1 0.7 -0.7 -0.6
Suffer from ‘nerves’ 0.8 1.2 4.6 -1.0 -0.8 -0.5 2.2 1.3 0.9 -0.6 0.5 -1.1
Overall health rating 1.6 3.4 9.4 -3.1 -2.8 -0.9 0.6 1.3 -1.9 -0.9 -2.4 -0.4
Chest pain or discomfort 0.4 0.6 1.6 -0.5 -1.3 -0.4 -0.9 -0.5 -0.6 -0.5 -1.2 0.1
Had major operations 0.5 0.5 2.2 -0.1 0.2 0.3 -0.8 -0.5 -0.9 -0.1 -1.5 -0.9
Age at last live birth 0.3 0.5 1.3 0.6 0.6 0.3 0.3 0.3 1.1 0.8 0.6 1.1
Family relationship satisfaction 0.9 1.2 6.5 -0.3 0.6 -1.0 0.6 0.8 1.0 -0.3 0.6 2.5
Leg pain on walking 1.5 1.9 6.0 -2.2 -1.0 -0.7 1.7 0.4 -0.4 -2.5 -0.2 -1.3
Qualifications: NVQ or HND or HNC or equivalent 0.8 1.0 2.4 0.8 1.0 1.5 -0.7 -1.0 -0.3 1.3 -0.4 1.1
Commuting to job workplace: Car/motor vehicle 2.0 2.3 8.5 -1.2 -1.1 -0.4 -1.1 0.1 -2.2 -0.6 -1.7 -2.9
Illness, injury, bereavement, stress in last 2 years 0.6 0.7 2.7 -0.2 0.6 0.4 1.2 -0.8 0.7 -0.4 1.6 -0.7
Medication: Aspirin 0.5 0.6 2.7 0.8 0.4 0.9 -0.6 -0.2 -0.0 1.7 -1.0 0.4
Supplements: Vitamin C 0.2 0.3 0.7 0.3 0.6 0.6 -0.8 -0.5 -0.9 -0.3 -0.1 -0.0
Knee pain experienced in last month 0.4 0.6 2.5 -0.1 -0.1 0.6 -0.6 -0.9 -1.6 0.8 -0.6 0.2
Hypertension (Self-reported) 1.4 3.8 7.9 -2.1 -1.8 -1.4 2.8 2.5 0.6 -2.8 0.0 -1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.7 2.0 3.3 1.8 1.5 1.8 -1.4 -0.9 -0.5 1.7 0.3 1.8
Illnesses of father: Heart disease 0.5 0.7 3.7 -0.0 -0.4 -0.6 0.6 1.9 1.0 0.5 -0.4 0.4
Illnesses of siblings: Diabetes 1.3 1.6 7.2 0.7 0.7 1.6 -0.5 -0.6 1.6 2.7 -0.0 0.4
Smoking status: Previous 0.5 0.8 2.7 -0.3 0.6 1.6 1.0 0.1 1.3 0.8 0.8 0.3
Forced expiratory volume in 1-second (FEV1), predicted 2.5 5.1 16.3 -0.2 -0.2 1.2 -3.6 -2.3 -4.0 -1.5 -2.0 -2.1
Whole body fat-free mass 0.5 2.7 8.2 0.6 0.6 0.8 -2.9 -2.1 -2.3 -0.3 -2.1 0.7
Leg fat-free mass (right) 0.6 3.3 9.4 1.3 1.7 1.6 -3.1 -2.6 -1.3 0.5 -1.6 1.4
Arm fat percentage (left) 0.5 2.0 6.8 0.2 0.6 1.5 -1.1 -2.6 -0.4 0.7 -2.2 1.4
Average weekly red wine intake 0.7 1.1 3.9 2.0 0.5 1.6 -0.0 -1.0 -0.0 0.2 0.7 1.2
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.5 0.1 -0.5 1.2 -0.0 -1.0 -1.2 -0.4 -0.0 -0.4
Mood swings 0.4 0.6 1.4 1.2 0.4 0.1 -0.6 -1.0 -0.6 1.1 -1.0 -0.2
Loneliness, isolation 0.3 0.5 1.9 -0.1 0.2 0.6 -0.1 -0.8 -1.4 0.3 -1.1 0.2
Long-standing illness, disability or infirmity 0.6 0.9 3.7 -1.9 -0.9 -0.8 0.0 0.6 -1.6 -0.1 -0.4 -0.4
Ever had bowel cancer screening 0.6 0.7 2.0 -1.4 -0.9 -0.3 0.6 0.1 -0.9 -1.4 -0.0 -0.2
Diabetes diagnosed by doctor 3.1 5.1 8.3 2.8 2.9 2.5 -2.8 -2.7 0.2 2.4 -0.5 1.3
Ever had stillbirth, spontaneous miscarriage or termination 1.8 2.0 8.5 -1.7 -0.1 0.2 -0.4 -1.4 -2.9 -0.4 -2.0 0.2
Friendships satisfaction 1.0 1.3 3.6 -0.4 -0.8 -0.9 1.3 1.7 0.8 -1.1 0.4 1.9
Qualifications: nursing, teaching 0.6 0.9 2.4 1.0 -1.4 0.3 -0.1 -0.2 -1.3 -0.4 -0.4 1.6
Commuting to job workplace: Walk 0.8 0.9 2.5 1.6 0.4 1.4 0.6 -1.0 0.9 0.4 1.1 0.1
Eye problems/disorders: Cataract 3.3 3.8 10.3 3.2 1.9 1.6 -0.9 -2.1 1.1 2.4 2.0 1.4
Mouth/teeth dental problems: Mouth ulcers 0.9 1.4 4.8 0.3 0.2 0.9 1.8 0.3 2.2 0.5 0.6 1.7
Medication for cholesterol 0.9 1.4 3.1 1.8 1.6 1.2 -1.1 -1.3 0.2 0.3 1.1 -0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 2.8 -0.7 -0.4 -0.6 -1.0 0.8 -0.7 -0.2 -1.7 0.2
Back pain experienced in last month 0.3 0.4 1.9 -1.4 0.2 0.0 1.0 0.2 -0.4 -0.3 -0.0 0.2
Mineral and other dietary supplements 0.6 0.7 2.0 0.8 1.0 0.7 -0.4 -0.0 1.4 1.0 0.5 1.1
Breast cancer (self-reported) 0.4 0.5 2.0 -1.4 -0.0 -1.1 0.4 0.9 -0.1 -0.2 0.6 0.3
Asthma (self-reported) 0.2 0.5 1.0 -0.8 -0.5 -1.0 -0.6 0.7 -0.9 -0.7 -0.2 0.3
Osteoporosis (self-reported) 0.4 0.5 1.7 -1.1 -0.1 -1.3 0.2 0.6 0.0 -0.6 0.8 0.7
Osteoarthritis (self-reported) 0.9 1.2 3.1 0.4 -1.4 0.1 0.4 -1.5 -1.6 0.4 -1.8 -0.1
Medication: Aspirin 0.4 0.5 2.3 0.6 0.1 0.9 -0.6 0.3 0.2 1.5 -0.9 0.0
Medication: Gliclazide 2.7 3.1 9.2 3.0 1.8 1.0 -1.4 -2.2 -0.2 2.6 -0.7 0.6
Illnesses of father: None of the above (group 1) 0.6 0.7 2.0 0.2 0.9 1.4 0.7 -0.6 -0.8 -0.2 1.4 -0.0
Smoking status: Current 0.8 1.3 4.0 -0.6 -0.0 -1.6 2.0 1.9 0.8 -0.1 0.2 0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.2 2.4 5.0 2.2 2.1 1.0 -1.6 -0.9 0.9 2.2 -0.4 1.6
Whole body water mass 0.5 2.6 7.7 0.6 0.7 0.9 -2.8 -2.1 -2.2 -0.2 -2.0 0.8
Leg predicted mass (right) 0.6 3.3 9.1 1.4 1.7 1.6 -3.0 -2.6 -1.3 0.6 -1.5 1.5
Arm fat mass (left) 0.7 2.8 8.2 0.3 0.4 1.3 -1.9 -2.9 -1.4 0.5 -2.8 1.2
Number of self-reported non-cancer illnesses 0.6 1.0 2.9 -1.7 -0.2 -0.9 1.5 0.8 0.7 -0.6 0.6 1.1
Average weekly champagne plus white wine intake 0.4 0.5 1.1 -0.6 -0.6 -0.5 0.6 1.1 0.9 0.4 0.3 0.9
Miserableness 1.4 2.4 7.0 -0.8 -0.5 -0.5 -1.3 -0.9 -2.4 -0.1 -2.3 -2.7
Guilty feelings 0.2 0.3 1.4 0.1 -0.1 -0.4 -0.3 -0.9 -1.2 -0.4 -0.5 -0.3
Wears glasses or contact lenses 0.2 0.2 1.1 0.1 0.0 0.5 0.3 0.1 0.3 -0.1 -0.0 1.1
Ever taken oral contraceptive pill 2.4 2.7 5.3 2.3 2.1 2.0 -1.5 -1.8 0.6 1.7 0.2 1.4
Hearing aid user 0.3 0.3 1.2 0.8 0.1 0.3 -0.0 0.0 -0.3 0.6 -0.7 1.1
Mother’s age at death 0.8 1.0 2.5 0.6 1.1 0.8 0.3 0.2 1.1 1.4 1.6 0.9
Financial situation satisfaction 0.7 0.8 2.8 0.8 0.7 1.1 -0.8 0.1 -0.3 0.6 1.7 1.0
Tinnitus: Yes, now most or all of the time 0.4 0.5 1.5 0.6 -0.0 0.4 -0.1 -0.8 1.2 -0.2 1.2 0.0
Commuting to job workplace: Public transport 1.0 1.2 4.6 -0.1 0.7 0.9 -2.1 -0.4 0.0 0.9 -0.3 2.2
Eye problems/disorders: Glaucoma 0.9 1.1 2.8 -1.5 -1.1 -1.0 0.7 1.7 0.5 -0.4 0.6 -1.2
Medication: Blood pressure 0.4 0.8 2.1 -1.4 -1.4 -0.8 0.9 0.9 -0.4 -0.2 -0.8 0.2
Pain type(s) experienced in last month: Hip pain 0.3 0.3 0.8 0.4 0.6 -0.5 0.2 -0.9 -0.7 0.5 0.0 0.8
Supplements: Fish oil (including cod liver oil) 0.8 1.0 3.7 -0.6 -1.2 -1.1 0.5 -0.0 -1.1 -1.0 -0.1 -1.9
High cholesterol (Self-reported) 0.2 0.3 1.1 0.3 -0.9 -0.2 1.1 0.0 -0.1 0.3 -0.4 0.8
Medication: Bendroflumethiazide 0.1 0.2 0.5 -0.6 0.2 0.4 0.6 0.0 -0.5 0.5 0.1 0.7
Medication: Paracetamol 0.5 0.8 3.6 0.5 0.4 0.7 -1.2 -1.9 -0.7 0.8 -0.2 0.4
Medication: Lisinopril 0.9 1.1 2.7 -0.2 -1.5 -1.0 1.0 -0.2 -1.3 -1.3 -1.6 -0.1
Medication: Atorvastatin 1.9 2.4 7.5 1.6 0.9 1.1 0.4 -0.5 1.7 2.7 0.6 2.4
Illnesses of father: High blood pressure 1.2 1.5 3.5 -1.0 -1.4 -1.3 0.4 1.9 1.3 -1.6 -0.8 0.5
Alcohol drinker status: Never 0.3 0.4 1.2 0.7 0.1 0.6 -1.1 -0.3 0.3 0.9 -0.3 0.8
Ever smoked 1.5 2.7 7.4 -1.1 0.1 -0.3 2.7 2.5 2.0 -0.7 1.9 -1.0
Basal metabolic rate 0.6 3.2 8.7 0.5 0.6 1.0 -3.0 -2.4 -2.4 -0.2 -2.4 0.8
Leg fat percentage (left) 0.3 1.2 5.2 0.2 -0.0 0.6 -0.4 -1.8 -0.3 1.3 -2.3 0.8
Arm fat-free mass (left) 0.5 2.7 6.7 0.4 0.2 0.2 -2.5 -2.1 -2.6 -0.0 -2.6 0.7
Number of operations (self-reported) 1.7 2.5 6.4 -0.0 0.1 -0.1 -1.7 -1.7 -2.5 1.0 -2.4 2.0
Average weekly beer plus cider intake 0.5 0.7 3.3 -0.5 -0.5 -0.1 0.5 -0.6 -1.8 -1.1 0.7 -0.7
Irritability 0.7 1.3 4.4 0.7 0.9 2.1 1.7 0.0 1.1 0.7 0.5 0.9
Risk taking 0.6 1.0 6.3 0.4 0.8 0.3 -0.1 -0.1 0.6 0.3 1.0 2.5
Ever had prostate specific antigen (PSA) test 0.4 0.5 1.9 -0.3 -0.6 0.3 1.4 -0.1 -0.4 -0.7 0.7 -1.0
Fractured/broken bones in last 5 years 0.1 0.2 0.5 -0.1 -0.5 -0.5 -0.1 -0.3 0.2 0.2 0.7 -0.7
Age started oral contraceptive pill 0.4 0.5 1.8 -0.1 0.8 0.4 0.2 -1.4 0.1 0.4 0.5 1.2
Diastolic blood pressure, automated reading 0.8 2.5 8.9 -1.3 -1.6 -1.6 2.1 1.5 0.2 -3.0 0.4 -0.2
Ever depressed for a whole week 0.9 1.2 2.8 -1.7 -0.2 -0.6 1.5 0.5 1.2 -1.2 0.1 1.3
Unable to work because of sickness or disability 0.7 0.9 2.6 -0.7 -0.4 -1.3 1.6 1.0 -0.8 -1.2 0.1 -0.3
Commuting to job workplace: Cycle 1.1 1.3 5.0 0.3 0.5 0.5 1.1 0.6 0.3 -0.0 2.1 2.2
Myopia 2.3 3.4 11.0 0.0 0.1 1.2 -2.2 -3.3 -2.6 0.8 -2.0 1.4
Vascular/heart problems diagnosed by doctor 0.8 2.1 6.4 1.0 1.1 1.1 -2.5 -1.8 -0.8 2.0 0.2 0.8
Cholesterol lowering medication 0.4 0.6 1.6 -0.7 -1.1 0.6 -0.1 -0.0 -0.7 0.2 -1.1 1.3
Medication: Omeprazole (e.g. Zanprol) 0.8 0.9 2.4 -1.2 -0.0 0.1 1.3 -0.6 -1.5 -1.0 -0.1 1.3
Pain experienced in last month 0.5 0.9 4.3 0.5 0.3 0.1 1.0 0.9 2.1 -0.1 0.9 0.9
Supplements: Calcium 0.9 0.9 2.4 -0.7 0.7 0.1 1.3 0.8 1.0 -0.2 1.6 -1.3
Basal cell carcinoma (self-reported) 0.8 1.0 2.7 -0.4 -1.6 0.0 0.1 -0.2 -1.1 -1.4 -1.6 -0.4
Heart attack/myocardial infarction (self-reported) 0.6 0.8 2.9 0.4 -0.5 -1.1 0.8 0.1 -0.8 0.1 -1.7 1.2
Deep venous thrombosis (DVT) (self-reported) 1.5 2.0 6.5 1.4 2.5 1.3 -0.2 -0.8 1.5 0.8 1.7 1.1
Heart disease (siblings) 1.4 1.7 4.4 -1.5 -1.1 -1.7 -0.7 1.1 -1.6 -0.9 -2.1 0.3
Alcohol drinker status: Previous 0.6 0.7 2.0 0.2 0.5 -0.6 -0.3 -1.4 -0.8 1.2 -1.2 0.6
Pack years of smoking 0.9 1.3 3.9 0.8 0.3 0.5 -1.0 -0.9 -1.1 1.7 -2.0 0.7
Impedance of whole body 0.7 3.4 10.7 -1.6 -1.9 -0.2 -1.2 -0.9 -2.9 -1.3 -1.2 -3.3
Leg fat mass (left) 0.6 2.3 8.0 0.2 0.2 0.7 -1.7 -2.5 -1.3 0.8 -2.8 0.8
Arm predicted mass (left) 0.6 2.9 7.3 0.6 0.3 0.3 -2.5 -2.2 -2.7 0.1 -2.5 0.6