Hub : Genes

ERC1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0960	0.0310	9.8e-06	0.025	0.036	0.055	0.046	0.055	4.9e-04	3.1e-05	3.0e-07	2.6e-06	3.0e-07
2	GTEx	Colon Sigmoid	0.2070	0.0880	8.6e-03	-0.007	NA	-0.008	NA	-0.003	6.6e-01	NA	9.1e-01	NA	4.2e-01
3	GTEx	Testis	0.3150	0.0800	3.5e-04	0.045	NA	0.113	NA	0.183	4.6e-03	NA	1.0e-05	NA	1.5e-08
4	METSIM	Adipose	0.0776	0.0230	7.8e-05	0.045	0.034	0.040	0.036	0.037	2.1e-07	7.1e-06	9.3e-07	3.4e-06	3.0e-06
5	TCGA	Breast Invasive Carcinoma	0.0313	0.0139	3.8e-03	0.034	0.017	0.029	NA	0.033	1.6e-07	1.8e-04	1.2e-06	NA	2.2e-07
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.1034	0.0323	2.8e-05	0.016	0.055	0.028	NA	0.019	5.7e-03	7.6e-07	3.7e-04	NA	2.8e-03
7	TCGA	Brain Lower Grade Glioma	0.0863	0.0367	5.0e-05	0.031	0.044	0.029	NA	0.030	1.7e-04	9.0e-06	2.4e-04	NA	2.2e-04
8	TCGA	Stomach Adenocarcinoma	0.1210	0.0490	2.7e-03	0.000	0.054	0.033	NA	0.015	3.5e-01	8.9e-05	1.9e-03	NA	2.9e-02
9	TCGA	Thyroid Carcinoma	0.0710	0.0420	2.5e-03	0.018	0.030	0.028	NA	0.036	6.2e-03	6.5e-04	8.2e-04	NA	1.7e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.5	0.9	2.0	-1.4	-1.1	-0.4	0.8	0.5	0.3	-0.8	-1.1	-1.3
Bipolar Disorder or Schizophrenia	0.5	1.3	3.3	-1.8	-0.2	0.4	1.8	1.2	1.1	-1.4	0.0	0.1
Depressed Affect (Nagel 2018)	0.4	0.8	2.7	0.6	-0.3	-0.1	-0.5	-1.6	-1.6	0.5	-1.0	-0.7
Depression (Nagel 2018)	0.9	1.4	5.9	-0.5	-1.5	-0.3	1.2	0.3	-1.4	-0.7	-0.3	-2.4
Intelligence (Savage-Jansen 2018)	0.7	2.3	6.2	2.5	2.1	1.6	0.1	-1.4	0.7	1.8	1.1	0.7
Neuroticism (Nagel 2018)	0.1	0.3	0.9	0.2	-1.0	-0.1	0.9	-0.2	-0.5	-0.0	-0.6	-0.4
Schizophrenia (2018)	0.6	1.3	2.7	-1.2	0.9	0.9	1.6	1.2	1.1	-1.2	1.0	1.2
Schizophrenia vs Biploar Disorder	0.1	0.2	0.8	0.1	-0.1	0.3	0.4	-0.3	0.0	-0.6	-0.1	0.9
Worry (Nagel 2018)	1.1	2.2	5.4	-1.1	-2.0	-1.2	2.3	2.3	0.8	-1.0	0.2	-1.0
Alzheimer’s Disease (in mother)	0.7	0.9	3.5	0.4	0.4	1.5	-0.3	-1.1	-0.1	0.2	1.9	0.3
Alzheimer’s Disease (in father)	0.7	0.7	1.8	-0.7	0.4	1.3	0.8	0.1	1.1	-0.5	1.2	0.8
Alzheimer’s Disease (including proxy)	1.5	2.2	8.9	0.4	1.2	3.0	-0.4	-1.5	0.4	0.4	2.3	1.0
Crohns Disease (2017)	0.8	1.8	8.4	-1.5	-0.1	1.1	2.9	0.4	1.1	0.1	1.8	0.1
Irritable Bowel Disease (IBD)	0.9	2.2	6.6	-1.9	-0.4	0.3	2.6	1.5	2.0	-0.1	1.7	-0.4
Ulcerative Colitis (UC)	0.6	1.1	3.5	-1.2	-0.5	-0.8	1.0	1.6	1.9	-0.0	0.5	-0.6
Major Depression (MDD)	1.2	1.4	5.0	-2.1	-0.0	0.6	0.7	0.4	-1.2	-2.2	-0.6	-1.0
Reaction Time	0.4	0.7	2.0	-1.4	-0.0	-0.5	0.8	1.1	1.4	-0.4	0.5	0.1
Verbal and Numeric Reasoning (VNR)	0.8	1.9	5.8	2.4	1.7	1.9	-0.7	-1.8	-0.4	1.1	0.0	0.4
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	0.2	0.2	0.5	0.5	0.4	-0.5	-0.2	0.0	-0.7	0.6	-0.4	-0.3
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.4	0.6	2.3	0.7	0.7	0.5	-0.2	-0.3	-0.1	1.3	0.4	1.5
Bipolar Disorder (2011)	0.9	0.8	2.8	-1.7	0.1	-0.2	0.5	1.5	0.4	-1.0	0.9	-0.5
Body Mass Index (BMI) (2010)	0.4	0.5	1.4	0.7	0.1	0.7	-1.2	-1.1	-0.1	0.6	-0.6	0.2
Coronary Artery Disease (CAD)	0.5	0.6	2.0	-0.7	-1.4	-1.0	0.9	0.6	-0.6	-0.7	-0.2	0.0
Crohns Disease (2012)	1.1	1.8	7.5	-1.0	0.3	1.7	2.7	0.3	1.1	0.1	1.4	1.1
Mean Putamen Volume	0.2	0.2	0.5	-0.5	0.2	-0.5	0.7	0.2	0.7	0.2	0.0	0.6
Fasting Glucose	0.4	0.5	1.5	1.1	-0.5	-0.6	0.0	-1.2	-0.4	0.6	-0.8	0.1
HbA1C	1.0	1.1	6.8	0.4	0.1	1.2	0.9	0.7	0.2	-0.5	2.6	-0.1
HDL Cholesterol	0.5	0.9	2.4	-1.3	-0.6	0.0	1.0	1.6	0.9	-0.8	1.1	-0.4
LDL Cholesterol	0.9	1.4	4.5	-0.9	-1.0	0.4	0.0	0.9	-1.6	-2.1	-0.1	-1.8
Lupus	0.3	0.4	0.8	-0.6	0.9	0.7	0.1	-0.6	0.9	-0.6	-0.5	-0.3
Neuroticism (2016)	0.7	1.0	5.3	1.3	-0.7	0.2	0.8	0.0	-0.6	-0.6	0.4	-2.3
Primary Biliary Cirrhosis	0.4	0.6	1.1	-0.4	0.8	1.0	1.1	0.0	0.9	0.7	0.9	0.8
Rheumatoid Arthritis	1.8	2.4	4.8	1.9	2.2	1.5	0.1	-1.7	0.9	1.8	0.7	2.0
Schizophrenia (2014)	0.5	1.1	1.8	-1.4	0.4	1.2	1.1	1.3	1.0	-1.1	0.6	1.0
Triglycerides	0.9	1.4	6.9	-0.7	-1.4	-0.2	0.1	0.1	-2.6	-0.8	-1.6	-0.6
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.5	0.5	0.1	-0.2	-0.6	0.0	1.4	1.6	0.2	-0.3
Ulcerative Colitis	0.2	0.3	1.1	-0.6	0.0	-0.4	0.1	-0.0	0.9	-0.1	0.4	-1.1
Blood Eosinophil Count	0.2	1.9	4.2	2.0	1.7	0.3	-1.4	-0.3	1.2	1.8	1.3	1.4
Blood Platelet Count	0.4	4.1	8.4	2.7	2.9	1.6	-1.6	-2.2	0.9	2.4	2.3	0.1
Blood Red Count	0.1	0.7	3.3	-0.9	-0.1	-0.7	0.3	0.5	1.0	0.1	-0.5	1.8
Blood White Count	0.6	4.4	10.2	1.9	3.0	0.6	0.9	-0.3	3.0	2.0	3.2	1.4
Heel T-Score	1.1	9.1	35.8	-3.4	-3.1	-6.0	-0.1	3.4	-3.6	-1.0	-0.6	-0.6
BMI	0.6	3.3	12.7	1.4	1.2	1.1	-0.3	-1.9	2.1	1.9	-0.9	3.6
Height	1.2	23.8	77.3	-2.3	-2.2	-0.0	-6.6	-2.8	-8.8	-3.5	-6.9	-4.1
Waist Hip Ratio (WHR)	1.9	8.5	22.2	2.7	1.8	3.2	-3.7	-4.7	-2.4	3.7	0.1	-0.0
Systolic Blood Pressure	0.7	3.5	7.2	-1.3	-1.5	-1.3	2.3	2.7	2.0	-2.0	2.1	-0.8
Smoking Status	0.3	0.8	2.3	-1.0	-0.6	-1.1	1.5	1.5	0.5	-0.2	-0.3	0.1
Allergy or Eczema	0.9	2.3	5.7	1.9	0.4	2.0	-0.3	0.2	2.3	1.3	2.4	0.1
Cardiovascular Disease	1.1	3.7	9.3	-1.5	-2.2	-1.8	3.0	2.6	1.2	-2.2	0.1	-0.6
Hypothyroidism (self reported)	0.5	1.1	3.4	-1.9	-0.6	-1.2	1.0	1.5	0.3	-1.1	0.2	-0.3
Respiratory disease	0.1	0.2	0.6	0.0	0.3	-0.2	-0.6	0.2	-0.2	0.2	0.5	0.8
Type 2 Diabetes (T2D) (2018)	3.1	5.9	15.2	2.8	3.9	2.1	-1.9	-2.6	1.7	2.5	1.1	2.1
Lung FEV1/FVC ratio	4.6	23.4	72.1	-1.2	0.0	-2.4	8.5	5.8	6.8	-0.9	7.0	-0.7
Lung FVC	3.3	16.7	37.8	4.5	3.8	3.7	-6.2	-4.6	-2.2	4.1	-2.9	3.7
Neuroticism	0.1	0.3	0.9	0.2	-0.8	-0.2	0.9	0.1	0.1	0.0	-0.4	-1.0
Chronotype (morning person)	0.3	0.8	2.2	0.4	1.3	-0.2	-0.2	-0.4	1.4	0.8	-0.3	1.5
Hair Pigment	0.0	1.2	3.1	1.0	-0.0	1.0	-1.7	-1.8	-0.9	-0.1	1.0	-1.0
Tanning	0.1	1.5	3.7	1.2	1.7	0.8	1.0	0.4	1.7	0.7	0.9	1.9
Hand grip strength (left)	0.2	0.6	2.2	-0.4	-0.4	0.6	-1.5	0.2	-1.1	-1.1	-0.4	0.3
Number of treatments/medications taken	0.2	0.4	1.0	-0.9	-0.1	-0.9	0.1	-0.2	-1.0	0.6	-0.3	0.2
Average weekly spirits intake	0.6	0.8	3.2	-0.7	-0.2	-0.8	0.8	1.2	-0.8	-0.2	0.1	1.8
Sensitivity / hurt feelings	0.6	1.0	2.8	1.5	1.0	0.4	0.5	-0.5	0.9	0.9	-0.6	1.7
Frequency of depressed mood in last 2 weeks	1.2	1.7	4.8	-0.7	-1.9	-0.6	0.7	0.9	-1.5	-0.5	-1.6	-2.2
Hearing difficulty/problems: Yes	0.7	1.0	4.8	0.5	0.1	-1.1	-0.6	-0.9	-1.1	0.3	-2.2	0.5
Relative age of first facial hair	1.0	2.1	7.2	-0.3	2.1	1.4	1.1	-0.4	1.2	0.9	2.7	-1.2
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	5.8	-0.5	0.9	0.2	0.1	0.3	-0.2	0.9	-0.2	2.4
Ever used hormone-replacement therapy (HRT)	0.5	0.7	1.3	0.7	0.0	-1.1	-0.1	-1.1	-0.7	0.6	-1.1	1.1
Ever had hysterectomy (womb removed)	0.8	1.0	3.3	-0.8	-0.3	-1.1	0.1	0.1	0.6	1.8	-0.7	1.5
Systolic blood pressure, automated reading	0.5	1.6	4.9	-1.3	-0.8	-1.0	1.4	1.2	1.3	-2.2	0.7	-0.0
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	2.0	0.4	0.2	1.0	-0.2	-0.5	0.2	1.4	-0.0	-0.1
Angina	1.0	1.3	6.0	0.4	0.7	0.7	0.8	-0.1	1.2	1.2	1.0	2.4
Medication for hormone replacement therapy	0.4	0.5	1.4	-0.4	-1.2	-0.9	-0.4	0.2	-0.4	0.2	-1.0	-0.4
Vitamin and mineral supplements	0.5	0.7	3.5	0.3	1.0	0.8	0.5	-0.6	0.3	0.5	0.2	1.9
Supplements: Zinc	0.4	0.4	1.3	-0.1	-0.2	-0.2	-0.9	0.8	-0.4	0.6	-0.5	-1.1
Medication: Co-codamol	0.4	0.5	2.3	-0.3	-0.2	-1.5	0.2	1.0	-0.0	0.4	-0.6	-0.3
Medication: Metformin	3.0	4.2	10.6	2.4	2.4	3.3	-1.5	-2.6	0.6	2.6	0.5	0.4
Diabetes (father)	1.0	1.2	3.2	0.8	0.2	0.6	-1.6	-1.6	-0.8	1.8	-0.3	0.9
Diabetes (mother)	0.3	0.3	0.9	-0.4	0.1	1.0	-0.2	-0.8	-0.2	0.7	-0.3	0.7
Severe depression (siblings)	0.4	0.4	1.0	0.1	0.6	0.8	0.0	-1.0	-0.0	0.8	0.7	0.8
Pack years adult smoking proportion	0.9	1.4	4.2	0.8	0.4	0.6	-1.1	-1.0	-1.2	1.9	-2.0	0.8
Impedance of leg (right)	1.1	5.5	12.9	-2.6	-3.4	-1.0	0.0	0.3	-3.2	-2.0	-1.5	-3.6
Leg fat-free mass (left)	0.6	3.4	10.2	0.9	1.3	1.4	-3.2	-2.7	-1.8	0.2	-2.0	1.2
Trunk fat percentage	1.0	4.0	12.2	-0.1	0.1	1.3	-2.2	-3.5	-2.2	0.6	-3.5	0.4
Hand grip strength (right)	0.4	1.2	4.4	-0.7	-1.2	0.1	-0.9	0.1	-1.6	-2.1	-0.9	-0.6
Townsend deprivation index at recruitment	0.5	0.7	3.1	-1.2	-0.6	0.6	-0.0	0.7	0.1	-0.7	-0.2	-1.8
Current tobacco smoking	0.8	1.3	3.8	-0.6	0.0	-1.5	1.9	2.0	0.7	-0.1	0.2	0.8
Average weekly fortified wine intake	0.3	0.4	1.5	-0.2	0.2	0.8	0.5	-0.2	0.8	1.2	0.1	0.6
Maternal smoking around birth	2.3	3.4	11.3	-0.5	0.4	0.2	-2.4	-2.7	-3.4	-0.3	-2.4	0.1
Fed-up feelings	0.4	0.8	2.4	0.3	-0.5	-0.0	0.3	-1.5	-1.1	0.6	-1.5	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	2.5	3.3	8.1	-1.8	-2.2	-1.1	1.6	0.6	-2.2	-2.0	-0.6	-2.9
Relative age voice broke	1.0	1.5	5.5	-1.0	1.3	0.3	1.3	0.4	0.9	-0.1	2.3	-1.5
Taking other prescription medications	0.6	0.9	4.3	-1.3	-1.1	0.4	-0.4	0.0	-2.1	0.3	-0.4	-0.2
Age when periods started (menarche)	0.6	1.4	4.1	0.3	-0.5	2.0	-0.7	-1.3	-1.6	-0.3	-0.2	-1.6
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	6.3	-0.1	-0.5	0.1	-1.7	-0.2	-1.6	-0.1	-2.5	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.8	-0.8	-1.1	-1.0	0.3	1.3	-0.6	-0.2	0.8	-0.6
Tinnitus: Yes, but not now, but have in the past	0.2	0.3	0.9	-0.5	0.1	-0.7	0.0	0.8	-0.1	-1.0	0.3	-0.2
Qualifications: CSEs or equivalent	1.1	1.5	5.6	-0.8	-0.8	-1.0	-1.1	0.3	-1.5	-1.2	-0.4	-2.4
Serious illness, injury or assault to yourself	0.3	0.3	1.0	-0.2	-0.2	-0.8	1.0	0.5	-0.4	0.4	-0.3	0.6
High blood pressure	0.9	2.6	5.9	-1.5	-1.4	-1.2	2.2	2.2	0.5	-2.4	-0.4	-1.6
Hayfever, allergic rhinitis or eczema	1.0	2.2	6.1	1.9	0.5	2.4	-0.3	-0.3	1.5	1.4	2.5	0.2
Multivitamins +/- minerals	0.7	0.9	4.5	0.5	0.1	0.1	-1.4	-0.7	0.4	0.7	0.0	-2.1
Stomach or abdominal pain in last month	1.4	1.7	5.2	2.3	1.2	-0.5	-0.5	-0.7	-0.9	2.2	0.6	1.3
Supplements: Glucosamine	0.4	0.6	1.6	-1.1	-0.1	0.7	0.8	0.4	-1.3	-0.8	-0.1	-0.4
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.8	-0.1	1.7	1.4	0.7	0.1	1.4	0.7	0.3	1.4
Medication: Atenolol	0.6	0.7	2.2	0.7	-0.2	0.8	0.6	-0.7	0.9	0.8	1.5	0.7
Medication: Levothyroxine sodium	0.8	1.3	3.1	-1.8	-1.2	-1.2	0.5	1.2	-0.6	-1.4	-1.2	0.4
Sitting height	1.3	9.3	32.8	0.1	-0.9	1.3	-4.6	-2.5	-5.7	-1.6	-4.1	-1.2
Chronic bronchitis/emphysema (father)	2.2	2.6	7.3	-0.5	-1.9	0.1	-1.8	-1.9	-2.7	-0.5	-1.9	-1.2
High blood pressure (mother)	0.2	0.3	1.7	-0.1	0.2	0.1	0.5	-0.1	-0.4	0.2	0.9	1.3
Body mass index (BMI)	0.5	2.0	6.1	1.0	1.2	1.0	-0.6	-2.0	0.5	1.3	-1.6	2.5
Impedance of leg (left)	0.8	3.8	13.0	-2.0	-2.8	-1.0	0.3	0.2	-2.5	-1.2	-1.0	-3.6
Leg predicted mass (left)	0.6	3.4	9.9	0.9	1.3	1.4	-3.2	-2.6	-1.8	0.1	-2.0	1.2
Trunk fat mass	1.1	4.9	14.8	-0.1	0.0	1.5	-2.7	-3.5	-2.7	0.3	-3.9	0.5
Waist circumference	1.1	4.2	13.5	1.5	1.2	2.1	-2.0	-3.7	-1.2	1.9	-1.8	1.8
Number of incorrect matches in round	0.4	0.6	2.0	-0.9	0.3	-0.0	1.4	0.6	1.2	0.1	0.9	0.6
Past tobacco smoking	0.6	1.2	3.8	0.6	-0.5	-0.9	-1.9	-1.0	-1.6	-0.4	-1.2	-0.3
Alcohol usually taken with meals	0.6	1.0	3.3	1.8	1.0	0.6	-0.1	-0.5	0.9	0.6	1.6	0.7
Nervous feelings	1.7	3.1	7.7	-1.4	-2.3	-1.4	2.8	2.2	1.5	-0.7	1.4	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	3.0	-0.5	-1.2	-1.1	1.5	1.7	-0.3	-0.2	-1.1	-0.5
Hearing difficulty/problems with background noise	0.5	0.9	1.6	-1.2	-1.1	-1.2	1.3	1.0	0.8	-0.8	-0.3	0.1
Hair/balding pattern: Pattern 2	3.2	4.0	7.4	2.4	2.5	1.7	-1.6	-2.7	-1.8	2.6	1.1	0.6
Had menopause	0.2	0.3	0.9	0.1	0.1	-0.7	0.6	-0.3	1.0	0.1	-0.2	0.7
Had other major operations	0.6	0.8	2.8	-1.7	0.4	0.4	0.9	1.0	0.0	0.1	0.6	1.3
Forced vital capacity (FVC)	2.2	8.3	31.2	1.9	1.9	2.6	-5.6	-3.1	-3.0	1.2	-2.6	1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	2.1	-0.5	-1.2	-0.8	-0.5	0.4	-1.4	-0.6	0.4	-0.5
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	3.5	-1.7	-0.1	-1.3	1.2	1.5	0.1	-1.9	-0.3	0.5
Qualifications: None of the above	2.3	4.9	14.6	-2.2	-1.9	-3.8	-0.2	1.0	-0.7	-1.1	-2.8	-3.2
Financial difficulties in last 2 years	0.6	0.8	2.0	1.3	1.3	1.4	-0.7	-0.1	0.1	-0.1	1.2	0.2
Mouth/teeth dental problems	0.6	0.8	2.8	-1.2	-0.0	-0.1	0.1	1.7	0.7	-1.5	0.4	-0.6
Heart attack	0.6	0.8	3.0	0.8	-0.1	-0.7	0.4	-0.5	-1.0	0.5	-1.7	1.1
Allergy	0.5	1.1	3.1	-1.2	-0.3	-1.3	0.4	-0.1	-1.0	-1.3	-1.8	-0.5
Pain all over the body in last month	0.4	0.4	1.1	-1.1	-0.5	-0.8	0.2	0.6	-0.2	-0.9	0.4	-0.4
Diabetes (self-reported)	2.6	4.1	7.5	2.7	2.4	1.5	-2.5	-2.4	0.3	2.7	-0.5	1.2
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	3.3	1.2	0.8	1.5	-0.7	-0.3	1.8	0.9	0.9	-0.4
Medication: Ramipril	0.6	0.8	1.5	-1.1	0.1	-1.2	1.1	1.1	0.5	0.1	-1.1	-0.0
Medication: Simvastatin	0.1	0.1	0.4	0.3	-0.0	0.4	0.6	0.1	-0.1	-0.3	-0.4	0.1
Fluid intelligence score	0.3	0.6	1.8	1.3	-0.0	1.4	-0.3	-1.1	-0.6	0.2	-0.2	-0.0
Illnesses of siblings	0.9	1.3	3.1	-0.9	-0.8	-0.9	1.5	1.5	-0.1	-1.1	1.8	-0.7
Neuroticism score	0.1	0.2	1.0	-0.0	-0.4	-0.1	0.8	-0.2	0.2	-0.1	-0.4	-1.0
Weight	0.9	4.4	11.1	0.5	0.6	1.3	-2.9	-3.3	-2.4	0.2	-3.3	1.2
Impedance of arm (right)	0.5	2.5	8.3	-1.0	-1.1	0.9	-1.9	-1.1	-2.9	-1.0	-0.7	-2.3
Arm fat percentage (right)	0.5	1.8	5.3	0.1	0.5	1.3	-1.1	-2.3	-0.7	0.6	-2.3	1.4
Trunk fat-free mass	0.4	2.4	7.0	0.2	-0.1	0.3	-2.6	-1.5	-2.7	-0.8	-2.1	0.2
Hip circumference	0.2	0.8	3.7	-0.4	-0.1	0.6	-0.1	-1.1	-0.2	-0.7	-1.9	1.3
Time employed in main current job	1.0	1.1	3.7	0.3	0.9	0.5	-1.8	-0.8	0.5	1.9	0.5	-0.9
Alcohol intake versus 10 years previously	1.5	2.2	5.8	-2.4	-1.5	-0.9	-1.2	2.1	-1.1	-0.4	-0.9	-1.8
Father’s age at death	2.0	2.7	8.0	0.8	1.1	-0.4	2.4	0.1	2.2	0.9	2.8	1.6
Worrier / anxious feelings	0.7	1.4	3.1	-0.4	-1.6	-1.4	1.3	1.8	0.1	-1.0	-1.1	-0.8
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	3.4	0.0	0.1	0.9	-0.9	-1.2	-1.8	0.5	-1.3	-0.1
Falls in the last year	1.3	1.7	8.9	0.4	1.9	-0.1	1.1	-0.9	0.1	0.3	0.9	3.0
Hair/balding pattern: Pattern 3	0.8	1.3	6.3	-0.1	0.8	-0.5	1.2	1.4	2.5	-0.1	0.7	0.6
Number of live births	0.9	1.3	2.4	-1.5	-1.3	-1.5	0.7	1.4	0.9	-0.8	-1.1	-0.2
Forced expiratory volume in 1-second (FEV1)	1.1	3.6	10.2	1.9	2.3	2.1	-3.2	-1.7	-0.7	1.6	-0.4	1.5
Pulse rate	1.1	1.9	4.3	-0.5	-1.4	-1.7	0.6	0.8	-1.9	-2.1	-1.9	-0.3
Happiness	0.3	0.4	1.1	-0.4	0.4	-0.3	1.0	1.0	-0.3	-0.5	0.4	0.7
Noisy workplace	0.3	0.4	2.1	0.6	-0.4	-1.5	0.1	-0.4	-0.4	0.2	-0.3	-0.4
Qualifications: A levels/AS levels or equivalent	1.3	2.9	6.1	2.0	0.4	2.0	0.9	0.5	2.5	0.0	2.2	2.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.9	0.1	0.6	0.6	-0.2	-0.2	-0.5	0.9	0.3	0.5
Mouth/teeth dental problems: Dentures	1.4	2.4	6.2	1.8	-0.1	0.5	-1.3	-2.3	-0.7	2.5	-0.4	2.0
Asthma	0.3	0.6	1.7	-0.9	-0.5	-1.3	-0.5	0.8	-0.7	-0.8	-0.3	0.1
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.2	4.0	0.7	0.5	0.4	-1.3	-1.9	-2.0	0.4	-0.7	0.6
Medication: Cholesterol lowering	0.7	1.1	2.6	1.6	0.9	0.1	1.5	-0.6	0.9	1.3	-0.0	1.2
Depression (self-reported)	1.0	1.2	5.4	-0.7	0.9	1.4	0.6	0.4	0.8	-0.7	2.3	-0.9
Medication: Lansoprazole	0.6	0.7	1.6	-1.1	-0.7	-0.0	0.5	0.7	-0.8	-1.3	-1.2	0.1
Prospective memory result	0.3	0.4	1.0	-0.4	0.5	0.5	-0.2	-0.4	0.4	0.8	-0.7	1.0
Lung cancer (father)	1.1	1.3	3.5	0.7	0.6	1.6	-1.9	-1.6	-0.6	0.1	-1.3	-0.6
Illnesses of mother	0.8	1.0	3.9	-1.1	-1.0	-0.2	-0.2	0.4	0.1	-0.6	-1.5	-2.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.1	8.2	2.4	2.6	2.2	-2.9	-2.0	-0.0	1.8	-0.0	1.9
Pulse wave Arterial Stiffness index	1.5	1.7	6.4	-1.8	-0.0	-0.9	0.3	1.1	-0.5	-1.1	-1.6	-2.5
Impedance of arm (left)	0.5	2.4	6.0	-1.1	-1.0	0.7	-1.8	-1.5	-2.4	-1.2	-0.7	-2.4
Arm fat mass (right)	0.7	2.7	7.6	0.4	0.6	1.3	-1.8	-2.7	-1.3	0.5	-2.7	1.4
Trunk predicted mass	0.4	2.3	7.1	0.3	-0.0	0.3	-2.6	-1.5	-2.7	-0.8	-2.1	0.2
Standing height	1.3	13.1	44.5	-1.0	-1.5	0.8	-5.4	-3.2	-6.7	-2.5	-4.1	-2.6
Length of working week for main job	0.7	0.7	2.3	0.8	1.1	1.5	-0.4	-0.4	0.7	0.3	0.8	1.0
Exposure to tobacco smoke at home	1.0	1.1	2.3	-0.7	-0.6	-1.5	1.1	1.4	0.0	-1.1	0.8	-1.3
Breastfed as a baby	0.8	0.9	3.6	0.6	0.8	0.7	1.2	0.1	1.9	0.2	1.4	0.2
Tense / ‘highly strung’	1.9	3.1	8.9	-0.6	-1.2	-1.2	3.0	2.8	2.4	-0.3	1.3	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	4.2	-2.0	-0.8	-1.1	1.3	1.9	1.0	-2.0	0.2	-0.6
Hair/balding pattern: Pattern 4	0.3	0.7	1.7	-1.3	-1.1	-0.9	-0.6	-0.3	-0.2	-0.9	-1.2	-0.1
Birth weight of first child	0.3	0.5	1.7	0.6	-0.7	-1.3	0.5	0.0	-0.6	-0.0	-0.4	-1.2
Peak expiratory flow (PEF)	0.5	1.2	2.9	1.7	1.4	0.9	-1.4	-0.4	-0.3	1.1	0.9	1.0
Pulse wave reflection index	0.4	0.5	1.4	-0.4	0.7	-0.2	-0.9	0.1	0.1	1.1	-1.2	0.4
Ever highly irritable/argumentative for 2 days	1.2	1.4	5.0	-2.2	-0.2	-0.9	0.9	1.6	-0.3	-1.3	0.5	1.1
Loud music exposure frequency	0.7	0.7	2.1	0.7	0.4	1.0	1.4	-0.2	1.1	-0.1	1.0	0.9
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	3.1	0.1	-0.4	1.5	0.4	1.2	1.0	0.2	1.8	1.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.6	1.3	1.1	0.5	-0.2	-0.6	-1.1	0.3	-0.2	-0.9
Blood clot in the leg (DVT)	1.3	1.6	4.9	1.3	2.2	1.0	-0.3	-0.8	1.3	1.0	1.7	1.0
Medication: Paracetamol	0.5	0.9	4.5	0.5	0.1	0.5	-0.7	-2.1	-1.1	0.6	-0.2	0.7
Headache pain in last month	1.5	2.5	8.6	1.5	0.7	1.1	-2.9	-2.4	-1.1	1.4	-0.6	-0.9
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.0	-1.0	-0.1	0.3	-0.8	0.4	0.4	-0.4	0.5	-0.1
Glaucoma (self-reported)	0.9	1.1	2.7	-1.6	-0.9	-0.8	0.6	1.3	0.2	-0.6	0.5	-1.6
Gout (self-reported)	0.5	0.7	3.3	-0.5	-0.5	-0.3	0.2	1.0	-1.1	0.3	-1.8	0.3
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	4.3	-2.1	-0.6	-0.6	1.1	1.1	0.5	-1.7	0.3	0.0
Medication: Amlodipine	0.4	0.6	1.7	0.7	-0.2	-1.3	-0.7	-0.4	-1.1	0.4	-0.8	-0.4
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.3	0.3	-0.1	-0.8	-0.5	0.2	-0.3	1.1	-0.4	0.1
Birth weight	0.9	1.9	4.9	-0.8	-0.5	-0.4	-0.5	-1.3	-2.1	-1.9	-0.9	-2.2
Chronic bronchitis/emphysema (mother)	0.8	1.0	5.3	0.7	1.0	1.0	-2.3	0.1	-0.6	0.7	-0.0	-0.3
High blood pressure (siblings)	0.4	0.6	2.6	0.9	-0.5	0.8	-0.4	-1.6	-0.4	0.7	-0.5	-0.1
Forced vital capacity (FVC), Best measure	2.0	7.5	25.0	2.5	2.4	2.8	-5.0	-3.4	-1.9	1.5	-1.5	1.8
Body fat percentage	0.8	3.1	10.1	0.0	0.1	1.1	-1.8	-3.1	-1.7	0.9	-3.2	0.7
Leg fat percentage (right)	0.4	1.3	6.4	-0.2	-0.4	0.6	-0.5	-1.6	-0.7	0.9	-2.5	0.7
Arm fat-free mass (right)	0.4	2.0	5.0	0.3	0.4	0.2	-2.2	-2.1	-2.0	-0.0	-2.1	0.6
Exposure to tobacco smoke outside home	2.6	3.4	7.7	-0.7	-1.6	-2.1	-1.6	0.3	-2.8	-1.0	-2.7	-2.2
Comparative body size at age 10	0.4	1.2	6.2	0.6	0.4	-0.1	0.5	-0.0	1.5	0.7	-1.1	2.5
Number of full brothers	0.8	0.9	3.5	-1.9	-0.5	-1.4	-0.2	0.5	-1.0	-0.4	0.4	-1.1
Worry too long after embarrassment	0.4	0.7	3.4	-0.8	-0.9	-0.7	0.8	-0.4	0.1	-0.2	-0.2	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.1	-0.7	-0.1	0.8	-0.3	0.1	0.3	-1.1	0.6	0.2
Wheeze or whistling in the chest in last year	0.2	0.4	0.8	0.9	-0.4	0.2	0.0	-0.7	-0.7	0.8	-0.3	0.8
Number of children fathered	0.3	0.4	1.1	-0.6	-0.1	-0.4	0.4	1.1	0.0	0.3	-0.9	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	2.3	0.4	0.2	-0.3	0.2	0.0	1.5	0.5	-0.0	1.5
Age at first live birth	0.4	0.6	2.7	1.6	-0.0	0.5	0.0	0.3	-0.1	1.0	-0.3	1.2
Pulse wave peak to peak time	1.3	1.5	4.7	1.8	0.1	1.1	-0.6	-1.4	0.0	1.0	1.3	2.2
Health satisfaction	0.8	1.0	2.7	-1.1	-0.6	-0.5	1.6	1.6	0.3	-0.6	-0.3	1.3
Shortness of breath walking on level ground	0.6	0.7	3.0	-0.6	-0.1	0.6	0.9	0.8	1.7	-0.3	0.7	0.6
Qualifications: College or University degree	0.9	2.8	7.4	2.5	1.2	0.7	1.9	-0.2	1.7	-0.0	1.9	2.7
Eye problems/disorders: None of the above	3.0	3.5	8.8	-3.0	-2.1	-1.7	0.5	1.6	-1.5	-2.6	-1.5	-1.0
Mouth/teeth dental problems: Loose teeth	0.8	1.0	2.7	-0.0	0.5	-0.1	-1.3	-1.6	-1.5	0.8	-0.7	0.8
Emphysema/chronic bronchitis	0.5	0.5	1.9	-0.1	-1.3	0.5	-0.9	0.2	-1.4	0.1	-0.4	-0.3
Medication for pain relief, constipation, heartburn	1.1	1.9	5.3	-1.2	-0.4	-0.9	1.4	2.3	2.1	-1.1	1.2	-0.8
Neck or shoulder pain in last month	0.6	0.8	4.4	-0.3	-0.9	-2.1	-0.1	0.2	-0.6	-0.8	-1.0	-0.0
Medication: Blood pressure	0.4	0.6	3.1	-0.1	-0.2	-1.0	1.8	0.9	0.5	-0.3	0.3	-0.3
Angina (self-reported)	0.7	0.9	4.3	0.1	0.5	0.3	0.8	0.2	0.9	1.0	0.9	2.1
Migraine (self-reported)	1.2	1.5	3.3	-1.5	-0.8	-1.1	-1.1	0.4	-1.8	-1.5	-1.5	-0.9
Medication: Ibuprofen	1.0	1.2	4.0	0.7	0.4	-0.0	-1.3	-1.7	-2.0	0.5	-0.9	0.7
Medication: Allopurinol	0.7	0.9	2.5	-1.2	-0.9	-0.6	0.7	0.8	-1.1	-0.1	-1.6	-0.8
Medication: Omeprazole	0.6	0.7	3.3	-0.6	0.0	0.5	0.7	-0.9	-0.9	-0.2	0.1	1.8
Medication: Seretide 50 evohaler	0.6	0.7	2.6	-0.0	-0.5	-0.2	-1.6	-0.9	-1.5	-0.2	-0.4	0.4
Mean time to correctly identify matches	0.1	0.3	0.7	-0.8	-0.1	-0.5	0.5	0.5	0.8	-0.6	-0.1	-0.2
Heart disease (mother)	0.6	0.7	2.1	1.4	1.1	0.0	-0.2	-1.1	0.8	0.9	0.5	0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.5	2.6	-1.4	-1.1	-1.1	1.6	1.6	-0.4	-1.2	-0.4	1.4
Whole body fat mass	1.0	4.3	13.8	0.2	0.1	1.2	-2.6	-3.3	-2.2	0.7	-3.7	0.8
Leg fat mass (right)	0.6	2.3	8.3	0.1	0.0	0.8	-1.8	-2.5	-1.2	0.7	-2.9	0.9
Arm predicted mass (right)	0.4	2.1	5.2	0.3	0.3	0.3	-2.3	-2.0	-2.1	-0.1	-2.1	0.5
Pulse rate, automated reading	0.3	0.9	5.5	0.6	-0.6	-0.2	-0.7	-1.0	-2.3	0.1	-0.5	-0.4
Alcohol intake frequency.	0.7	1.7	7.1	-0.7	-1.4	-0.9	-2.7	0.1	-1.2	0.7	-1.3	-1.2
Comparative height size at age 10	1.3	7.3	15.8	-2.9	-2.5	-0.6	-2.9	-0.6	-4.0	-3.0	-3.2	-2.8
Number of full sisters	0.6	0.7	1.6	1.2	0.9	-1.2	-1.0	-0.3	0.1	0.7	-0.7	-0.6
Suffer from ‘nerves’	0.8	1.2	4.6	-1.0	-0.8	-0.5	2.2	1.3	0.9	-0.6	0.5	-1.1
Overall health rating	1.6	3.4	9.4	-3.1	-2.8	-0.9	0.6	1.3	-1.9	-0.9	-2.4	-0.4
Chest pain or discomfort	0.4	0.6	1.6	-0.5	-1.3	-0.4	-0.9	-0.5	-0.6	-0.5	-1.2	0.1
Had major operations	0.5	0.5	2.2	-0.1	0.2	0.3	-0.8	-0.5	-0.9	-0.1	-1.5	-0.9
Age at last live birth	0.3	0.5	1.3	0.6	0.6	0.3	0.3	0.3	1.1	0.8	0.6	1.1
Family relationship satisfaction	0.9	1.2	6.5	-0.3	0.6	-1.0	0.6	0.8	1.0	-0.3	0.6	2.5
Leg pain on walking	1.5	1.9	6.0	-2.2	-1.0	-0.7	1.7	0.4	-0.4	-2.5	-0.2	-1.3
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	2.4	0.8	1.0	1.5	-0.7	-1.0	-0.3	1.3	-0.4	1.1
Commuting to job workplace: Car/motor vehicle	2.0	2.3	8.5	-1.2	-1.1	-0.4	-1.1	0.1	-2.2	-0.6	-1.7	-2.9
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	2.7	-0.2	0.6	0.4	1.2	-0.8	0.7	-0.4	1.6	-0.7
Medication: Aspirin	0.5	0.6	2.7	0.8	0.4	0.9	-0.6	-0.2	-0.0	1.7	-1.0	0.4
Supplements: Vitamin C	0.2	0.3	0.7	0.3	0.6	0.6	-0.8	-0.5	-0.9	-0.3	-0.1	-0.0
Knee pain experienced in last month	0.4	0.6	2.5	-0.1	-0.1	0.6	-0.6	-0.9	-1.6	0.8	-0.6	0.2
Hypertension (Self-reported)	1.4	3.8	7.9	-2.1	-1.8	-1.4	2.8	2.5	0.6	-2.8	0.0	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	2.0	3.3	1.8	1.5	1.8	-1.4	-0.9	-0.5	1.7	0.3	1.8
Illnesses of father: Heart disease	0.5	0.7	3.7	-0.0	-0.4	-0.6	0.6	1.9	1.0	0.5	-0.4	0.4
Illnesses of siblings: Diabetes	1.3	1.6	7.2	0.7	0.7	1.6	-0.5	-0.6	1.6	2.7	-0.0	0.4
Smoking status: Previous	0.5	0.8	2.7	-0.3	0.6	1.6	1.0	0.1	1.3	0.8	0.8	0.3
Forced expiratory volume in 1-second (FEV1), predicted	2.5	5.1	16.3	-0.2	-0.2	1.2	-3.6	-2.3	-4.0	-1.5	-2.0	-2.1
Whole body fat-free mass	0.5	2.7	8.2	0.6	0.6	0.8	-2.9	-2.1	-2.3	-0.3	-2.1	0.7
Leg fat-free mass (right)	0.6	3.3	9.4	1.3	1.7	1.6	-3.1	-2.6	-1.3	0.5	-1.6	1.4
Arm fat percentage (left)	0.5	2.0	6.8	0.2	0.6	1.5	-1.1	-2.6	-0.4	0.7	-2.2	1.4
Average weekly red wine intake	0.7	1.1	3.9	2.0	0.5	1.6	-0.0	-1.0	-0.0	0.2	0.7	1.2
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.5	0.1	-0.5	1.2	-0.0	-1.0	-1.2	-0.4	-0.0	-0.4
Mood swings	0.4	0.6	1.4	1.2	0.4	0.1	-0.6	-1.0	-0.6	1.1	-1.0	-0.2
Loneliness, isolation	0.3	0.5	1.9	-0.1	0.2	0.6	-0.1	-0.8	-1.4	0.3	-1.1	0.2
Long-standing illness, disability or infirmity	0.6	0.9	3.7	-1.9	-0.9	-0.8	0.0	0.6	-1.6	-0.1	-0.4	-0.4
Ever had bowel cancer screening	0.6	0.7	2.0	-1.4	-0.9	-0.3	0.6	0.1	-0.9	-1.4	-0.0	-0.2
Diabetes diagnosed by doctor	3.1	5.1	8.3	2.8	2.9	2.5	-2.8	-2.7	0.2	2.4	-0.5	1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.8	2.0	8.5	-1.7	-0.1	0.2	-0.4	-1.4	-2.9	-0.4	-2.0	0.2
Friendships satisfaction	1.0	1.3	3.6	-0.4	-0.8	-0.9	1.3	1.7	0.8	-1.1	0.4	1.9
Qualifications: nursing, teaching	0.6	0.9	2.4	1.0	-1.4	0.3	-0.1	-0.2	-1.3	-0.4	-0.4	1.6
Commuting to job workplace: Walk	0.8	0.9	2.5	1.6	0.4	1.4	0.6	-1.0	0.9	0.4	1.1	0.1
Eye problems/disorders: Cataract	3.3	3.8	10.3	3.2	1.9	1.6	-0.9	-2.1	1.1	2.4	2.0	1.4
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	4.8	0.3	0.2	0.9	1.8	0.3	2.2	0.5	0.6	1.7
Medication for cholesterol	0.9	1.4	3.1	1.8	1.6	1.2	-1.1	-1.3	0.2	0.3	1.1	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.8	-0.7	-0.4	-0.6	-1.0	0.8	-0.7	-0.2	-1.7	0.2
Back pain experienced in last month	0.3	0.4	1.9	-1.4	0.2	0.0	1.0	0.2	-0.4	-0.3	-0.0	0.2
Mineral and other dietary supplements	0.6	0.7	2.0	0.8	1.0	0.7	-0.4	-0.0	1.4	1.0	0.5	1.1
Breast cancer (self-reported)	0.4	0.5	2.0	-1.4	-0.0	-1.1	0.4	0.9	-0.1	-0.2	0.6	0.3
Asthma (self-reported)	0.2	0.5	1.0	-0.8	-0.5	-1.0	-0.6	0.7	-0.9	-0.7	-0.2	0.3
Osteoporosis (self-reported)	0.4	0.5	1.7	-1.1	-0.1	-1.3	0.2	0.6	0.0	-0.6	0.8	0.7
Osteoarthritis (self-reported)	0.9	1.2	3.1	0.4	-1.4	0.1	0.4	-1.5	-1.6	0.4	-1.8	-0.1
Medication: Aspirin	0.4	0.5	2.3	0.6	0.1	0.9	-0.6	0.3	0.2	1.5	-0.9	0.0
Medication: Gliclazide	2.7	3.1	9.2	3.0	1.8	1.0	-1.4	-2.2	-0.2	2.6	-0.7	0.6
Illnesses of father: None of the above (group 1)	0.6	0.7	2.0	0.2	0.9	1.4	0.7	-0.6	-0.8	-0.2	1.4	-0.0
Smoking status: Current	0.8	1.3	4.0	-0.6	-0.0	-1.6	2.0	1.9	0.8	-0.1	0.2	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.4	5.0	2.2	2.1	1.0	-1.6	-0.9	0.9	2.2	-0.4	1.6
Whole body water mass	0.5	2.6	7.7	0.6	0.7	0.9	-2.8	-2.1	-2.2	-0.2	-2.0	0.8
Leg predicted mass (right)	0.6	3.3	9.1	1.4	1.7	1.6	-3.0	-2.6	-1.3	0.6	-1.5	1.5
Arm fat mass (left)	0.7	2.8	8.2	0.3	0.4	1.3	-1.9	-2.9	-1.4	0.5	-2.8	1.2
Number of self-reported non-cancer illnesses	0.6	1.0	2.9	-1.7	-0.2	-0.9	1.5	0.8	0.7	-0.6	0.6	1.1
Average weekly champagne plus white wine intake	0.4	0.5	1.1	-0.6	-0.6	-0.5	0.6	1.1	0.9	0.4	0.3	0.9
Miserableness	1.4	2.4	7.0	-0.8	-0.5	-0.5	-1.3	-0.9	-2.4	-0.1	-2.3	-2.7
Guilty feelings	0.2	0.3	1.4	0.1	-0.1	-0.4	-0.3	-0.9	-1.2	-0.4	-0.5	-0.3
Wears glasses or contact lenses	0.2	0.2	1.1	0.1	0.0	0.5	0.3	0.1	0.3	-0.1	-0.0	1.1
Ever taken oral contraceptive pill	2.4	2.7	5.3	2.3	2.1	2.0	-1.5	-1.8	0.6	1.7	0.2	1.4
Hearing aid user	0.3	0.3	1.2	0.8	0.1	0.3	-0.0	0.0	-0.3	0.6	-0.7	1.1
Mother’s age at death	0.8	1.0	2.5	0.6	1.1	0.8	0.3	0.2	1.1	1.4	1.6	0.9
Financial situation satisfaction	0.7	0.8	2.8	0.8	0.7	1.1	-0.8	0.1	-0.3	0.6	1.7	1.0
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.5	0.6	-0.0	0.4	-0.1	-0.8	1.2	-0.2	1.2	0.0
Commuting to job workplace: Public transport	1.0	1.2	4.6	-0.1	0.7	0.9	-2.1	-0.4	0.0	0.9	-0.3	2.2
Eye problems/disorders: Glaucoma	0.9	1.1	2.8	-1.5	-1.1	-1.0	0.7	1.7	0.5	-0.4	0.6	-1.2
Medication: Blood pressure	0.4	0.8	2.1	-1.4	-1.4	-0.8	0.9	0.9	-0.4	-0.2	-0.8	0.2
Pain type(s) experienced in last month: Hip pain	0.3	0.3	0.8	0.4	0.6	-0.5	0.2	-0.9	-0.7	0.5	0.0	0.8
Supplements: Fish oil (including cod liver oil)	0.8	1.0	3.7	-0.6	-1.2	-1.1	0.5	-0.0	-1.1	-1.0	-0.1	-1.9
High cholesterol (Self-reported)	0.2	0.3	1.1	0.3	-0.9	-0.2	1.1	0.0	-0.1	0.3	-0.4	0.8
Medication: Bendroflumethiazide	0.1	0.2	0.5	-0.6	0.2	0.4	0.6	0.0	-0.5	0.5	0.1	0.7
Medication: Paracetamol	0.5	0.8	3.6	0.5	0.4	0.7	-1.2	-1.9	-0.7	0.8	-0.2	0.4
Medication: Lisinopril	0.9	1.1	2.7	-0.2	-1.5	-1.0	1.0	-0.2	-1.3	-1.3	-1.6	-0.1
Medication: Atorvastatin	1.9	2.4	7.5	1.6	0.9	1.1	0.4	-0.5	1.7	2.7	0.6	2.4
Illnesses of father: High blood pressure	1.2	1.5	3.5	-1.0	-1.4	-1.3	0.4	1.9	1.3	-1.6	-0.8	0.5
Alcohol drinker status: Never	0.3	0.4	1.2	0.7	0.1	0.6	-1.1	-0.3	0.3	0.9	-0.3	0.8
Ever smoked	1.5	2.7	7.4	-1.1	0.1	-0.3	2.7	2.5	2.0	-0.7	1.9	-1.0
Basal metabolic rate	0.6	3.2	8.7	0.5	0.6	1.0	-3.0	-2.4	-2.4	-0.2	-2.4	0.8
Leg fat percentage (left)	0.3	1.2	5.2	0.2	-0.0	0.6	-0.4	-1.8	-0.3	1.3	-2.3	0.8
Arm fat-free mass (left)	0.5	2.7	6.7	0.4	0.2	0.2	-2.5	-2.1	-2.6	-0.0	-2.6	0.7
Number of operations (self-reported)	1.7	2.5	6.4	-0.0	0.1	-0.1	-1.7	-1.7	-2.5	1.0	-2.4	2.0
Average weekly beer plus cider intake	0.5	0.7	3.3	-0.5	-0.5	-0.1	0.5	-0.6	-1.8	-1.1	0.7	-0.7
Irritability	0.7	1.3	4.4	0.7	0.9	2.1	1.7	0.0	1.1	0.7	0.5	0.9
Risk taking	0.6	1.0	6.3	0.4	0.8	0.3	-0.1	-0.1	0.6	0.3	1.0	2.5
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.9	-0.3	-0.6	0.3	1.4	-0.1	-0.4	-0.7	0.7	-1.0
Fractured/broken bones in last 5 years	0.1	0.2	0.5	-0.1	-0.5	-0.5	-0.1	-0.3	0.2	0.2	0.7	-0.7
Age started oral contraceptive pill	0.4	0.5	1.8	-0.1	0.8	0.4	0.2	-1.4	0.1	0.4	0.5	1.2
Diastolic blood pressure, automated reading	0.8	2.5	8.9	-1.3	-1.6	-1.6	2.1	1.5	0.2	-3.0	0.4	-0.2
Ever depressed for a whole week	0.9	1.2	2.8	-1.7	-0.2	-0.6	1.5	0.5	1.2	-1.2	0.1	1.3
Unable to work because of sickness or disability	0.7	0.9	2.6	-0.7	-0.4	-1.3	1.6	1.0	-0.8	-1.2	0.1	-0.3
Commuting to job workplace: Cycle	1.1	1.3	5.0	0.3	0.5	0.5	1.1	0.6	0.3	-0.0	2.1	2.2
Myopia	2.3	3.4	11.0	0.0	0.1	1.2	-2.2	-3.3	-2.6	0.8	-2.0	1.4
Vascular/heart problems diagnosed by doctor	0.8	2.1	6.4	1.0	1.1	1.1	-2.5	-1.8	-0.8	2.0	0.2	0.8
Cholesterol lowering medication	0.4	0.6	1.6	-0.7	-1.1	0.6	-0.1	-0.0	-0.7	0.2	-1.1	1.3
Medication: Omeprazole (e.g. Zanprol)	0.8	0.9	2.4	-1.2	-0.0	0.1	1.3	-0.6	-1.5	-1.0	-0.1	1.3
Pain experienced in last month	0.5	0.9	4.3	0.5	0.3	0.1	1.0	0.9	2.1	-0.1	0.9	0.9
Supplements: Calcium	0.9	0.9	2.4	-0.7	0.7	0.1	1.3	0.8	1.0	-0.2	1.6	-1.3
Basal cell carcinoma (self-reported)	0.8	1.0	2.7	-0.4	-1.6	0.0	0.1	-0.2	-1.1	-1.4	-1.6	-0.4
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.9	0.4	-0.5	-1.1	0.8	0.1	-0.8	0.1	-1.7	1.2
Deep venous thrombosis (DVT) (self-reported)	1.5	2.0	6.5	1.4	2.5	1.3	-0.2	-0.8	1.5	0.8	1.7	1.1
Heart disease (siblings)	1.4	1.7	4.4	-1.5	-1.1	-1.7	-0.7	1.1	-1.6	-0.9	-2.1	0.3
Alcohol drinker status: Previous	0.6	0.7	2.0	0.2	0.5	-0.6	-0.3	-1.4	-0.8	1.2	-1.2	0.6
Pack years of smoking	0.9	1.3	3.9	0.8	0.3	0.5	-1.0	-0.9	-1.1	1.7	-2.0	0.7
Impedance of whole body	0.7	3.4	10.7	-1.6	-1.9	-0.2	-1.2	-0.9	-2.9	-1.3	-1.2	-3.3
Leg fat mass (left)	0.6	2.3	8.0	0.2	0.2	0.7	-1.7	-2.5	-1.3	0.8	-2.8	0.8
Arm predicted mass (left)	0.6	2.9	7.3	0.6	0.3	0.3	-2.5	-2.2	-2.7	0.1	-2.5	0.6