Best TWAS P=2.63e-11 · Best GWAS P=7.97e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HHIPL1 | 0.08 | 0.04 | lasso | 3 | 0.03 | 6.4e-05 | -4.7 | 5.1 | 3.0e-07 | -0.85 | 0.06 | 0.92 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | HHIPL1 | 0.35 | 0.09 | enet | 25 | 0.14 | 3.9e-11 | -6.4 | -6.0 | 2.6e-09 | 0.80 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Esophageal Carcinoma | CYP46A1 | 0.20 | 0.00 | blup | 65 | 0.08 | 1.6e-03 | -4.5 | 5.3 | 1.4e-07 | -0.60 | 0.01 | 0.56 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | HHIPL1 | 0.05 | 0.02 | blup | 57 | 0.02 | 1.5e-03 | 5.1 | -5.3 | 9.8e-08 | 0.64 | 0.03 | 0.82 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HHIPL1 | 0.05 | 0.06 | lasso | 2 | 0.05 | 6.1e-06 | -6.5 | -6.2 | 7.7e-10 | 0.99 | 0.00 | 1.00 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | HHIPL1 | 0.09 | 0.11 | lasso | 3 | 0.10 | 3.2e-06 | -6.5 | -6.7 | 2.6e-11 | 0.99 | 0.00 | 1.00 | TRUE |