TWAS
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Traits
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Lung FEV1/FVC ratio
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chr15:73,524,629-74,915,888
Best TWAS P=1.01e-10 · Best GWAS P=3.34e-12 conditioned to 3.53e-10
73.6M
73.8M
74M
74.2M
74.4M
74.6M
74.8M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Thyroid
LOXL1-AS1
0.15
0.03
enet
40
0.03
0.0026
4
-6.5
1e-10
-0.11
0.15
0.05
TRUE