[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr1:200,740,278-202,607,593

Best TWAS P=1.49e-10 · Best GWAS P=1.47e-13 conditioned to 1.26e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	LMOD1	0.04	0.07	enet	6	0.05	9.4e-07	6.4	6.4	1.5e-10	-0.02	0.00	1.00	TRUE
11	GTEx	Skin Not Sun Exposed Suprapubic	RP11-134G8.8	0.43	0.18	lasso	4	0.24	2.9e-13	4.4	5.6	1.8e-08	0.54	0.98	0.02	TRUE
1	GTEx	Adipose Subcutaneous	SHISA4	0.09	0.04	lasso	3	0.03	1.5e-03	5.2	6.0	1.6e-09	0.00	0.27	0.09	FALSE
14	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SHISA4	0.03	0.01	enet	5	0.00	2.5e-01	6.4	5.7	9.7e-09	-0.03	0.00	0.93	FALSE
4	GTEx	Cells Transformed fibroblasts	SHISA4	0.19	0.05	enet	23	0.11	2.5e-08	-1.2	5.7	1.6e-08	-0.02	0.78	0.10	FALSE
12	GTEx	Skin Sun Exposed Lower leg	RP11-134G8.8	0.35	0.23	lasso	6	0.31	8.2e-26	4.4	5.6	1.8e-08	0.52	1.00	0.00	FALSE
5	GTEx	Colon Sigmoid	RP11-134G8.8	0.41	0.32	lasso	4	0.30	2.3e-11	4.4	5.5	3.3e-08	0.56	0.77	0.22	FALSE
9	GTEx	Muscle Skeletal	RP11-134G8.8	0.19	0.11	lasso	4	0.13	5.1e-13	4.4	5.5	3.3e-08	0.55	0.98	0.02	FALSE
6	GTEx	Esophagus Mucosa	RP11-134G8.8	0.43	0.32	lasso	8	0.34	3.2e-23	4.4	5.5	4.0e-08	0.51	1.00	0.00	FALSE
3	GTEx	Artery Aorta	RP11-134G8.8	0.19	0.15	enet	8	0.22	1.6e-12	4.4	5.5	4.2e-08	0.57	0.99	0.01	FALSE
7	GTEx	Esophagus Muscularis	RP11-134G8.8	0.39	0.29	lasso	3	0.32	2.6e-20	4.4	5.4	5.3e-08	0.53	1.00	0.00	FALSE
8	GTEx	Lung	RP11-134G8.8	0.23	0.17	lasso	3	0.22	5.0e-17	4.4	5.3	9.6e-08	0.53	1.00	0.00	FALSE
10	GTEx	Nerve Tibial	RP11-134G8.8	0.40	0.33	enet	10	0.31	1.5e-22	4.4	5.3	1.3e-07	0.51	1.00	0.00	FALSE
13	METSIM	Adipose	LMOD1	0.09	0.07	bslmm	496	0.07	4.8e-10	-4.8	5.3	1.3e-07	0.07	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	RP11-134G8.8	0.20	0.09	enet	15	0.12	2.9e-10	4.4	5.2	2.0e-07	0.41	1.00	0.00	FALSE