TWAS
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Lung FEV1/FVC ratio
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chr16:72,122,463-73,789,190
Best TWAS P=1.2e-07 · Best GWAS P=2.7e-07 conditioned to 0.673
72.2M
72.4M
72.6M
72.8M
73M
73.2M
73.4M
73.6M
73.8M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Testis
ZFHX3
0.28
0.1
lasso
5
0.11
1.8e-05
5.1
5.3
1.2e-07
0.95
0.01
0.99
TRUE