[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr17:60,013,554-61,464,730

Best TWAS P=2.84e-19 · Best GWAS P=2.92e-18 conditioned to 0.000231

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Cells Transformed fibroblasts	MRC2	0.10	0.02	enet	17	0.02	1.5e-02	6.6	-9.0	2.8e-19	0.66	0.01	0.94	TRUE
2	GTEx	Lung	MRC2	0.13	0.01	enet	12	0.06	1.6e-05	7.7	-7.9	3.7e-15	0.28	0.23	0.21	FALSE
3	The Cancer Genome Atlas	Esophageal Carcinoma	METTL2A	0.14	0.03	blup	16	0.04	2.4e-02	-3.1	-6.2	4.7e-10	0.06	0.00	0.40	FALSE