[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr17:61,765,524-63,531,331

Best TWAS P=2.63e-18 · Best GWAS P=2.42e-17 conditioned to 1.77e-06

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SMURF2	0.10	0.01	blup	14	0.05	5.5e-03	-7.7	-8.7	2.6e-18	0.52	0.00	0.77	TRUE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	PLEKHM1P	0.02	0.02	blup	7	0.02	6.7e-03	-8.5	8.0	1.0e-15	-0.95	0.00	0.87	TRUE
2	GTEx	Artery Tibial	DDX5	0.12	0.13	lasso	2	0.12	1.5e-09	5.9	-6.0	2.6e-09	-0.10	1.00	0.00	TRUE
3	GTEx	Cells Transformed fibroblasts	SMURF2	0.17	0.13	enet	8	0.13	3.7e-10	-8.2	-8.7	4.0e-18	0.77	0.01	0.99	FALSE
5	GTEx	Skin Sun Exposed Lower leg	hsa-mir-6080	0.11	0.10	lasso	2	0.08	1.7e-07	-8.0	8.2	3.1e-16	-0.72	0.03	0.97	FALSE
11	The Cancer Genome Atlas	Lung Adenocarcinoma	PLEKHM1P	0.02	0.01	blup	7	0.02	4.7e-03	-8.5	8.0	1.6e-15	-0.92	0.00	0.76	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PLEKHM1P	0.24	0.26	lasso	6	0.27	8.0e-33	-7.1	7.6	4.0e-14	-0.89	0.06	0.94	FALSE
9	The Cancer Genome Atlas	Glioblastoma Multiforme	PLEKHM1P	0.08	0.04	blup	7	0.04	2.7e-02	-7.2	7.4	1.2e-13	-0.89	0.00	0.45	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	PLEKHM1P	0.04	0.03	blup	7	0.05	1.2e-05	-7.1	7.4	1.4e-13	-0.90	0.01	0.99	FALSE
4	GTEx	Pancreas	MILR1	0.18	0.01	lasso	7	0.03	1.3e-02	-8.0	-6.3	2.2e-10	0.59	0.02	0.76	FALSE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	PLEKHM1P	0.01	0.01	enet	7	0.01	1.9e-02	-8.5	5.9	3.5e-09	-0.79	0.00	0.94	FALSE
6	NTR	Blood	DDX5	0.10	0.04	lasso	3	0.04	5.2e-13	5.9	-5.8	6.4e-09	-0.12	1.00	0.00	FALSE
7	YFS	Blood	DDX5	0.42	0.21	bslmm	215	0.21	7.7e-68	5.9	-5.5	3.1e-08	-0.15	1.00	0.00	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLEKHM1P	0.08	0.03	enet	4	0.04	4.0e-05	-7.1	5.2	1.5e-07	-0.69	0.06	0.75	FALSE