TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Lung FEV1/FVC ratio
:
←
→
chr17:76,320,835-77,734,689
Best TWAS P=1.01e-07 · Best GWAS P=3.06e-08 conditioned to 1.67e-08
76.4M
76.6M
76.8M
77M
77.2M
77.4M
77.6M
77.8M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Thyroid Carcinoma
C1QTNF1
0.05
0.04
enet
10
0.05
9.4e-06
-4.3
-5.3
1e-07
-0.02
0.00
0.57
TRUE
1
GTEx
Artery Tibial
C1QTNF1
0.14
0.03
enet
12
0.09
1.4e-07
4.1
-5.1
3e-07
0.10
0.61
0.16
FALSE