[Hub]/) : Traits : Lung FEV1/FVC ratio :

chr17:79,280,925-80,680,449

Best TWAS P=8.75e-10 · Best GWAS P=2.61e-08 conditioned to 0.293

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex STRA13 0.45 0.38 lasso 4 0.40 1.6e-51 -5.2 5.3 9.0e-08 -0.95 0.02 0.97 FALSE
2 GTEx Adipose Subcutaneous STRA13 0.28 0.26 lasso 3 0.26 5.0e-21 -5.2 5.2 2.0e-07 -0.92 0.02 0.98 FALSE
3 GTEx Adipose Visceral Omentum STRA13 0.18 0.15 lasso 4 0.14 8.0e-08 -5.2 -5.3 1.3e-07 0.91 0.02 0.98 FALSE
4 GTEx Artery Aorta STRA13 0.20 0.14 enet 16 0.11 7.9e-07 -5.2 6.1 8.7e-10 -0.81 0.02 0.97 TRUE
5 GTEx Artery Tibial STRA13 0.37 0.22 enet 14 0.22 1.6e-17 -5.2 6.0 1.6e-09 -0.89 0.02 0.98 FALSE
6 GTEx Cells Transformed fibroblasts STRA13 0.19 0.23 lasso 1 0.22 4.9e-16 -5.2 5.2 2.4e-07 -0.92 0.02 0.98 FALSE
7 GTEx Colon Sigmoid STRA13 0.36 0.26 enet 16 0.24 3.9e-09 -5.2 5.2 2.5e-07 -0.89 0.01 0.99 FALSE
8 GTEx Colon Transverse STRA13 0.26 0.08 enet 18 0.05 1.6e-03 -5.2 5.5 4.4e-08 -0.74 0.02 0.96 FALSE
9 GTEx Esophagus Mucosa STRA13 0.19 0.14 lasso 2 0.12 2.8e-08 -5.2 5.5 3.8e-08 -0.91 0.02 0.98 FALSE
10 GTEx Esophagus Muscularis STRA13 0.40 0.33 lasso 2 0.32 4.2e-20 -5.2 5.2 2.1e-07 -0.92 0.02 0.98 FALSE
11 GTEx Heart Atrial Appendage STRA13 0.25 0.15 enet 4 0.16 1.2e-07 -5.0 5.3 1.2e-07 -0.95 0.01 0.99 FALSE
12 GTEx Lung STRA13 0.16 0.16 lasso 3 0.15 1.2e-11 -5.2 5.3 9.0e-08 -0.95 0.02 0.98 FALSE
13 GTEx Muscle Skeletal STRA13 0.20 0.09 lasso 6 0.10 5.4e-10 -5.2 5.5 2.9e-08 -0.97 0.00 1.00 FALSE
14 GTEx Nerve Tibial STRA13 0.18 0.17 enet 2 0.12 1.4e-08 -5.2 5.2 2.4e-07 -0.92 0.02 0.98 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic STRA13 0.23 0.18 enet 5 0.10 6.6e-06 -5.2 5.7 1.1e-08 -0.92 0.02 0.98 FALSE
16 GTEx Skin Sun Exposed Lower leg STRA13 0.12 0.13 lasso 3 0.12 7.9e-10 -5.2 5.1 2.8e-07 -0.92 0.02 0.98 FALSE
17 GTEx Thyroid STRA13 0.40 0.34 lasso 5 0.34 2.3e-26 -5.2 5.1 3.0e-07 -0.92 0.02 0.98 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma STRA13 0.07 0.12 lasso 6 0.10 3.2e-10 -5.6 5.3 1.4e-07 -0.99 0.00 1.00 FALSE