[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr18:7,329,035-11,250,447

Best TWAS P=5.04e-18 · Best GWAS P=1.06e-29 conditioned to 6.89e-31

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Nerve Tibial	SOGA2	0.17	0.08	lasso	7	0.05	1.5e-04	-8.9	8.7	5.0e-18	-0.02	0.05	0.92	TRUE
4	GTEx	Brain Nucleus accumbens basal ganglia	NAPG	0.34	0.20	lasso	4	0.23	6.9e-07	-5.5	5.6	2.7e-08	-0.05	0.88	0.01	TRUE
3	GTEx	Brain Cerebellum	RP11-21J18.1	0.38	-0.01	lasso	6	-0.01	5.2e-01	5.5	-5.5	4.2e-08	0.04	0.06	0.14	TRUE
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	KIAA0802	0.12	0.02	enet	15	0.08	1.8e-08	3.9	-5.4	5.4e-08	-0.03	0.71	0.02	TRUE
10	The Cancer Genome Atlas	Brain Lower Grade Glioma	PTPRM	0.06	0.05	lasso	1	0.04	4.7e-05	-5.1	5.1	2.8e-07	0.06	0.10	0.87	TRUE
8	ROSMAP	Brain Pre-frontal Cortex	SOGA2	0.09	0.04	lasso	6	0.04	2.1e-06	-8.9	8.7	5.1e-18	-0.01	0.03	0.97	FALSE
5	GTEx	Lung	SOGA2	0.14	0.09	lasso	5	0.08	1.2e-06	-7.1	-7.0	2.9e-12	0.04	0.12	0.88	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	KIAA0802	0.06	0.04	lasso	6	0.04	1.6e-09	-5.5	-6.8	8.2e-12	0.05	0.74	0.26	FALSE
7	GTEx	Testis	SOGA2	0.27	0.15	lasso	5	0.17	5.1e-08	-5.1	5.6	2.1e-08	-0.03	0.07	0.93	FALSE
1	GTEx	Artery Coronary	NAPG	0.26	0.23	lasso	1	0.19	5.7e-07	-5.5	5.5	2.9e-08	-0.05	0.89	0.01	FALSE
2	GTEx	Artery Tibial	NAPG	0.17	0.15	lasso	2	0.12	1.3e-09	-5.5	5.5	4.2e-08	-0.05	1.00	0.00	FALSE