[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr18:7,329,035-11,250,447

Best TWAS P=5.04e-18 · Best GWAS P=1.06e-29 conditioned to 6.89e-31

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Coronary NAPG 0.26 0.23 lasso 1 0.19 5.7e-07 -5.5 5.5 2.9e-08 -0.05 0.89 0.01 FALSE
2 GTEx Artery Tibial NAPG 0.17 0.15 lasso 2 0.12 1.3e-09 -5.5 5.5 4.2e-08 -0.05 1.00 0.00 FALSE
3 GTEx Brain Cerebellum RP11-21J18.1 0.38 -0.01 lasso 6 -0.01 5.2e-01 5.5 -5.5 4.2e-08 0.04 0.06 0.14 TRUE
4 GTEx Brain Nucleus accumbens basal ganglia NAPG 0.34 0.20 lasso 4 0.23 6.9e-07 -5.5 5.6 2.7e-08 -0.05 0.88 0.01 TRUE
5 GTEx Lung SOGA2 0.14 0.09 lasso 5 0.08 1.2e-06 -7.1 -7.0 2.9e-12 0.04 0.12 0.88 FALSE
6 GTEx Nerve Tibial SOGA2 0.17 0.08 lasso 7 0.05 1.5e-04 -8.9 8.7 5.0e-18 -0.02 0.05 0.92 TRUE
7 GTEx Testis SOGA2 0.27 0.15 lasso 5 0.17 5.1e-08 -5.1 5.6 2.1e-08 -0.03 0.07 0.93 FALSE
8 ROSMAP Brain Pre-frontal Cortex SOGA2 0.09 0.04 lasso 6 0.04 2.1e-06 -8.9 8.7 5.1e-18 -0.01 0.03 0.97 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma KIAA0802 0.06 0.04 lasso 6 0.04 1.6e-09 -5.5 -6.8 8.2e-12 0.05 0.74 0.26 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma PTPRM 0.06 0.05 lasso 1 0.04 4.7e-05 -5.1 5.1 2.8e-07 0.06 0.10 0.87 TRUE
11 The Cancer Genome Atlas Prostate Adenocarcinoma KIAA0802 0.12 0.02 enet 15 0.08 1.8e-08 3.9 -5.4 5.4e-08 -0.03 0.71 0.02 TRUE