Best TWAS P=8.05e-10 · Best GWAS P=1.1e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | EVI5L | 0.12 | 0.00 | lasso | 4 | 0.00 | 2.8e-01 | -5.8 | -5.3 | 1.2e-07 | 0.89 | 0.02 | 0.73 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ARHGEF18 | 0.05 | 0.04 | lasso | 5 | 0.04 | 4.1e-05 | -5.8 | -6.1 | 8.1e-10 | 0.95 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARHGEF18 | 0.06 | 0.00 | lasso | 4 | 0.01 | 1.7e-02 | -6.4 | -5.5 | 3.4e-08 | 0.88 | 0.01 | 0.81 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | ARHGEF18 | 0.03 | 0.01 | blup | 72 | 0.00 | 1.4e-01 | 4.6 | -5.6 | 1.7e-08 | 0.78 | 0.02 | 0.42 | FALSE |