TWAS
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Usage
Models
Genes
Traits
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Traits
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Lung FEV1/FVC ratio
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chr19:31,077,263-32,530,559
Best TWAS P=5.34e-18 · Best GWAS P=6.17e-36 conditioned to 3.66e-22
31M
31.2M
31.4M
31.6M
31.8M
32M
32.2M
32.4M
32.6M
0
10
20
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
TSHZ3
0.19
0.02
enet
32
0.13
2.5e-40
7.3
-8.7
5.3e-18
0.44
0.36
0.64
TRUE
1
NTR
Blood
TSHZ3
0.05
0.00
blup
390
0.03
6.1e-09
-5.5
-6.4
1.9e-10
0.43
0.08
0.82
FALSE