[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr19:36,181,046-37,950,253

Best TWAS P=2.8e-09 · Best GWAS P=8.38e-09 conditioned to 0.639

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue AC092295.7 0.11 0.06 lasso 4 0.08 8.7e-05 -5.6 5.5 3.5e-08 -0.85 0.02 0.90 FALSE
2 GTEx Breast Mammary Tissue (Male) AC092295.7 0.10 0.06 lasso 3 0.03 6.5e-02 -5.7 5.8 6.2e-09 -0.98 0.03 0.64 FALSE
3 GTEx Colon Sigmoid CTD-2630F21.1 0.09 0.02 lasso 11 0.07 1.5e-03 4.3 -5.7 1.1e-08 0.76 0.06 0.69 FALSE
4 GTEx Heart Atrial Appendage ZNF850 0.08 0.03 enet 15 0.06 1.6e-03 4.3 -5.9 4.1e-09 0.62 0.07 0.78 FALSE
5 GTEx Lung AC092295.7 0.05 0.03 lasso 8 0.04 3.9e-04 -5.0 5.7 9.7e-09 -0.89 0.02 0.97 FALSE
6 GTEx Pancreas ZNF260 0.12 0.06 lasso 4 0.06 2.1e-03 -5.6 5.9 2.8e-09 -0.94 0.02 0.94 TRUE
7 GTEx Skin Not Sun Exposed Suprapubic AC092295.7 0.09 0.07 lasso 4 0.06 4.4e-04 -5.7 5.8 5.8e-09 -0.93 0.03 0.94 FALSE
8 GTEx Skin Sun Exposed Lower leg ZFP82 0.06 0.03 lasso 5 0.04 4.0e-04 -5.7 5.6 2.0e-08 -0.91 0.02 0.96 FALSE
9 GTEx Testis ZNF567 0.16 0.19 lasso 1 0.17 3.9e-08 -5.7 5.8 9.0e-09 -1.00 0.01 0.99 FALSE
10 GTEx Testis AC092295.7 0.13 0.07 lasso 6 0.08 1.6e-04 -5.7 5.8 6.2e-09 -0.96 0.01 0.97 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma ZNF567 0.02 0.03 blup 44 0.02 1.5e-05 4.3 -5.2 2.6e-07 0.77 0.46 0.53 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma ZNF382 0.07 0.07 lasso 3 0.07 3.7e-08 -4.8 -5.3 1.5e-07 0.87 0.08 0.92 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma ZNF382 0.04 0.04 lasso 3 0.03 2.3e-04 -4.8 -5.2 1.7e-07 0.93 0.01 0.97 FALSE