Best TWAS P=6.22e-09 · Best GWAS P=9.4e-09 conditioned to 0.173
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PYGB | 0.13 | 0.01 | enet | 21 | 0.08 | 4.2e-07 | -5.1 | -5.2 | 2.3e-07 | 0.57 | 0.03 | 0.90 | FALSE |
| 2 | GTEx | Brain Cerebellum | CTD-2514C3.1 | 0.21 | 0.05 | lasso | 5 | 0.15 | 3.5e-05 | -5.7 | 5.8 | 6.2e-09 | -0.87 | 0.01 | 0.94 | TRUE |
| 3 | GTEx | Breast Mammary Tissue (Female) | VN1R108P | 0.15 | 0.11 | lasso | 6 | 0.09 | 1.5e-03 | -5.3 | -5.3 | 1.3e-07 | 0.62 | 0.02 | 0.86 | FALSE |
| 4 | GTEx | Esophagus Mucosa | PYGB | 0.12 | 0.01 | enet | 19 | 0.02 | 9.7e-03 | -5.0 | -5.5 | 4.2e-08 | 0.54 | 0.02 | 0.87 | FALSE |
| 5 | GTEx | Esophagus Muscularis | PYGB | 0.22 | 0.19 | enet | 13 | 0.21 | 1.1e-12 | -5.1 | -5.5 | 4.9e-08 | 0.54 | 0.02 | 0.98 | FALSE |