[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr20:43,293,270-44,801,026

Best TWAS P=7.17e-16 · Best GWAS P=3.13e-11 conditioned to 0.118

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	SYS1-DBNDD2	0.02	0.00	blup	81	0.01	4.8e-04	-6.0	-8.1	7.2e-16	0.68	0.02	0.79	TRUE
3	GTEx	Colon Transverse	DBNDD2	0.29	0.20	lasso	3	0.20	9.8e-10	-6.4	-7.0	2.8e-12	0.97	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Thyroid Carcinoma	SYS1-DBNDD2	0.06	0.04	blup	81	0.03	1.4e-03	-6.1	-6.9	6.6e-12	0.84	0.01	0.93	FALSE
7	GTEx	Skin Sun Exposed Lower leg	DBNDD2	0.38	0.26	enet	9	0.26	3.5e-21	-6.6	-6.7	2.1e-11	0.99	0.00	1.00	FALSE
4	GTEx	Esophagus Mucosa	DBNDD2	0.41	0.37	lasso	7	0.36	1.6e-25	-6.4	-6.5	9.3e-11	1.00	0.00	1.00	FALSE
2	GTEx	Artery Tibial	DBNDD2	0.19	0.16	lasso	3	0.14	2.8e-11	-6.4	-6.4	1.5e-10	0.99	0.01	0.99	FALSE
8	NTR	Blood	SYS1	0.06	0.03	bslmm	488	0.03	6.5e-11	-6.4	-6.3	2.2e-10	0.97	0.01	0.99	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	DBNDD2	0.22	0.17	enet	25	0.17	1.4e-09	-6.4	-6.2	5.5e-10	0.86	0.01	0.99	FALSE
5	GTEx	Esophagus Muscularis	DBNDD2	0.17	0.14	lasso	4	0.11	2.3e-07	-6.1	-6.2	6.7e-10	0.94	0.01	0.99	FALSE
1	CommonMind	Brain Pre-frontal Cortex	WFDC2	0.08	0.00	bslmm	497	0.02	1.9e-03	4.0	-6.0	1.8e-09	0.09	0.09	0.03	FALSE
11	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SYS1-DBNDD2	0.03	0.02	enet	6	0.02	2.4e-03	4.6	-6.0	1.8e-09	0.58	0.15	0.48	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SYS1-DBNDD2	0.06	0.02	blup	81	0.03	9.2e-05	4.6	-6.0	2.4e-09	0.34	0.69	0.04	FALSE