TWAS
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About
Usage
Models
Genes
Traits
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Traits
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Lung FEV1/FVC ratio
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chr2:8,649,517-10,229,911
Best TWAS P=8.51e-20 · Best GWAS P=4.2e-30 conditioned to 3.75e-12
8.6M
8.8M
9M
9.2M
9.4M
9.6M
9.8M
10M
10.2M
0
5
10
15
20
25
30
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Tibial
ASAP2
0.18
0.05
enet
19
0.14
4.9e-11
8.6
9.1
8.5e-20
0.73
0.01
0.99
TRUE
2
The Cancer Genome Atlas
Esophageal Carcinoma
ASAP2
0.15
-0.01
blup
109
0.01
1.8e-01
4.8
5.7
1.4e-08
0.51
0.01
0.43
FALSE