[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr2:151,570,279-153,056,846

Best TWAS P=1.08e-09 · Best GWAS P=7.7e-10 conditioned to 0.21

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RIF1 0.11 0.07 lasso 4 0.07 8.0e-09 5.42 -5.3 1.2e-07 -0.77 0.12 0.88 FALSE
2 GTEx Adrenal Gland RIF1 0.14 0.04 lasso 2 0.05 6.4e-03 5.42 -5.9 4.7e-09 -0.75 0.07 0.62 FALSE
3 GTEx Artery Aorta RIF1 0.22 0.14 lasso 3 0.17 1.5e-09 5.42 -5.5 4.8e-08 -0.74 0.18 0.82 FALSE
4 GTEx Artery Coronary RIF1 0.28 0.09 lasso 6 0.09 6.8e-04 5.42 -5.3 1.1e-07 -0.74 0.04 0.93 FALSE
5 GTEx Artery Tibial RIF1 0.20 0.17 lasso 3 0.23 2.8e-18 -3.72 -5.2 2.0e-07 -0.67 0.58 0.42 FALSE
6 GTEx Brain Putamen basal ganglia RIF1 0.21 0.02 enet 10 0.03 7.4e-02 0.53 -5.1 2.8e-07 -0.56 0.05 0.50 FALSE
7 GTEx Breast Mammary Tissue (Male) RIF1 0.42 0.18 lasso 9 0.26 7.5e-07 -3.74 -5.5 3.4e-08 -0.61 0.09 0.78 FALSE
8 GTEx Cells Transformed fibroblasts RIF1 0.11 0.07 enet 12 0.08 1.2e-06 5.42 -5.3 1.2e-07 -0.83 0.02 0.98 FALSE
9 GTEx Colon Sigmoid RIF1 0.25 0.14 lasso 8 0.10 1.9e-04 5.42 -5.7 1.4e-08 -0.79 0.06 0.87 FALSE
10 GTEx Colon Transverse RIF1 0.20 0.04 lasso 7 0.06 7.5e-04 6.15 -6.0 1.7e-09 -0.85 0.01 0.98 FALSE
11 GTEx Esophagus Gastroesophageal Junction RIF1 0.15 0.13 lasso 5 0.16 1.8e-06 5.42 -5.2 1.5e-07 -0.69 0.20 0.58 FALSE
12 GTEx Lung RIF1 0.15 0.12 lasso 2 0.17 4.0e-13 5.42 -5.3 1.2e-07 -0.70 0.21 0.79 FALSE
13 GTEx Pancreas RIF1 0.16 0.11 lasso 3 0.08 2.7e-04 5.42 -5.4 7.6e-08 -0.80 0.03 0.93 FALSE
14 GTEx Prostate RIF1 0.33 0.14 enet 20 0.24 1.2e-06 -4.43 -5.5 4.2e-08 -0.60 0.17 0.67 FALSE
15 GTEx Spleen RIF1 0.39 0.25 lasso 3 0.20 9.1e-06 5.42 -5.2 2.0e-07 -0.76 0.08 0.74 FALSE
16 METSIM Adipose RIF1 0.04 0.04 lasso 7 0.03 2.2e-05 5.42 -6.1 1.1e-09 -0.94 0.01 0.99 TRUE