[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr2:119,497,419-121,675,485

Best TWAS P=1.73e-09 · Best GWAS P=2.09e-08 conditioned to 0.215

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Skin Sun Exposed Lower leg	TMEM37	0.08	0.03	lasso	5	0.01	1.0e-01	4.9	6.0	1.7e-09	0.32	0.12	0.46	TRUE
7	GTEx	Testis	TMEM185B	0.12	0.09	enet	10	0.12	5.7e-06	4.7	5.4	6.2e-08	0.77	0.15	0.83	TRUE
8	METSIM	Adipose	TMEM37	0.05	0.01	bslmm	411	0.02	1.3e-03	4.5	5.9	3.1e-09	0.23	0.24	0.11	FALSE
5	GTEx	Cells Transformed fibroblasts	PTPN4	0.06	0.02	lasso	2	0.03	1.5e-03	5.6	5.9	4.1e-09	0.99	0.04	0.95	FALSE
11	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TMEM37	0.06	0.00	blup	58	0.02	2.4e-02	-3.9	5.7	1.6e-08	0.00	0.02	0.32	FALSE
3	GTEx	Brain Cerebellum	PTPN4	0.15	0.09	lasso	4	0.04	1.9e-02	5.0	-5.6	1.7e-08	-0.86	0.08	0.78	FALSE
4	GTEx	Brain Cerebellum	AC012363.4	0.34	0.06	lasso	5	0.08	1.9e-03	5.0	-5.6	1.7e-08	-0.89	0.05	0.80	FALSE
2	GTEx	Brain Cerebellar Hemisphere	EPB41L5	0.33	0.22	lasso	16	0.20	1.0e-05	5.6	-5.6	1.8e-08	-0.98	0.04	0.93	FALSE
9	YFS	Blood	PTPN4	0.02	0.01	lasso	2	0.02	1.8e-06	5.5	-5.3	9.3e-08	-0.84	0.04	0.95	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TMEM185B	0.03	0.03	lasso	3	0.02	5.2e-03	5.2	5.3	9.5e-08	0.79	0.00	0.90	FALSE
12	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	TMEM185B	0.07	0.03	blup	21	0.03	1.3e-02	5.2	5.2	1.7e-07	0.73	0.01	0.74	FALSE
1	GTEx	Artery Tibial	TMEM185B	0.07	0.06	lasso	5	0.04	3.4e-04	4.7	5.2	2.3e-07	0.72	0.13	0.80	FALSE