Best TWAS P=9.72e-10 · Best GWAS P=3.32e-08 conditioned to 0.332
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | AC009506.1 | 0.07 | 0.05 | lasso | 3 | 0.03 | 1.8e-03 | -5.5 | 5.5 | 3.3e-08 | -1.00 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Artery Aorta | AC009506.1 | 0.12 | 0.03 | lasso | 3 | 0.02 | 1.7e-02 | -5.5 | 5.3 | 1.1e-07 | -0.93 | 0.02 | 0.90 | FALSE |
| 3 | GTEx | Artery Tibial | AC009506.1 | 0.11 | 0.11 | lasso | 4 | 0.10 | 5.5e-08 | -5.4 | 5.3 | 9.0e-08 | -0.92 | 0.02 | 0.98 | FALSE |
| 4 | GTEx | Thyroid | MARCH7 | 0.06 | 0.01 | lasso | 15 | 0.01 | 7.8e-02 | 4.7 | 6.1 | 9.7e-10 | -0.81 | 0.04 | 0.91 | TRUE |