Best TWAS P=9.8e-10 · Best GWAS P=4.82e-19 conditioned to 3.94e-14
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | VGLL4 | 0.04 | 0.02 | blup | 511 | 0.02 | 7.8e-04 | 4.4 | 6.0 | 2.5e-09 | -0.04 | 0.62 | 0.01 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | VGLL4 | 0.05 | 0.03 | blup | 422 | 0.04 | 3.7e-06 | 5.0 | 6.1 | 9.8e-10 | -0.27 | 0.95 | 0.00 | TRUE |