TWAS
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Usage
Models
Genes
Traits
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Traits
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Lung FEV1/FVC ratio
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chr3:3,574,205-5,232,074
Best TWAS P=4.61e-09 · Best GWAS P=5.24e-15 conditioned to 6.36e-07
3.6M
3.8M
4M
4.2M
4.4M
4.6M
4.8M
5M
5.2M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Testis
ITPR1-AS1
0.27
0.05
lasso
4
0.07
5.4e-04
4.82
5.9
4.6e-09
0.80
0.00
0.98
TRUE
2
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
SUMF1
0.11
0.01
blup
450
0.04
2.1e-05
0.39
-5.4
8.4e-08
-0.24
0.17
0.12
TRUE