[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr3:44,079,200-45,500,950

Best TWAS P=3.1e-08 · Best GWAS P=4.66e-08 conditioned to 0.122

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Breast Mammary Tissue (Female)	KIAA1143	0.11	0.00	lasso	8	0.06	9.2e-03	-4.1	-5.5	3.1e-08	0.83	0.04	0.61	TRUE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	KIAA1143	0.01	0.01	enet	8	0.01	1.3e-03	-5.3	-5.5	4.0e-08	0.98	0.01	0.94	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	KIAA1143	0.03	0.00	blup	34	0.00	1.1e-01	-5.1	-5.5	4.3e-08	0.96	0.01	0.60	FALSE
1	GTEx	Adipose Subcutaneous	KIAA1143	0.21	0.20	lasso	6	0.20	5.6e-16	-5.1	-5.4	5.7e-08	0.98	0.01	0.99	FALSE
2	GTEx	Adipose Visceral Omentum	KIAA1143	0.23	0.15	enet	25	0.14	7.7e-08	-5.1	-5.3	1.2e-07	0.92	0.02	0.98	FALSE
3	GTEx	Breast Mammary Tissue	KIAA1143	0.08	0.12	enet	5	0.09	1.7e-05	-4.9	-5.3	1.4e-07	0.97	0.02	0.97	FALSE
8	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	KIAA1143	0.03	0.01	blup	28	0.01	1.9e-02	-5.1	-5.3	1.4e-07	0.94	0.01	0.72	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	KIAA1143	0.05	0.07	lasso	6	0.06	9.1e-07	-5.1	-5.2	1.7e-07	0.96	0.01	0.99	FALSE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	KIAA1143	0.10	0.10	lasso	2	0.10	1.8e-06	-5.3	-5.2	2.3e-07	0.96	0.01	0.98	FALSE
12	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	KIAA1143	0.14	0.10	enet	15	0.09	1.3e-04	-5.3	-5.2	2.5e-07	0.97	0.01	0.98	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	KIAA1143	0.15	0.16	lasso	5	0.13	1.0e-07	-5.3	-5.2	2.6e-07	0.98	0.02	0.98	FALSE
7	GTEx	Skin Sun Exposed Lower leg	KIAA1143	0.16	0.16	lasso	7	0.16	2.0e-13	-5.1	-5.1	2.7e-07	0.97	0.02	0.98	FALSE
5	GTEx	Ovary	KIAA1143	0.24	0.26	lasso	5	0.19	1.7e-05	-5.1	-5.1	2.9e-07	0.97	0.02	0.97	FALSE