[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr3:44,079,200-45,500,950

Best TWAS P=3.1e-08 · Best GWAS P=4.66e-08 conditioned to 0.122

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous KIAA1143 0.21 0.20 lasso 6 0.20 5.6e-16 -5.1 -5.4 5.7e-08 0.98 0.01 0.99 FALSE
2 GTEx Adipose Visceral Omentum KIAA1143 0.23 0.15 enet 25 0.14 7.7e-08 -5.1 -5.3 1.2e-07 0.92 0.02 0.98 FALSE
3 GTEx Breast Mammary Tissue KIAA1143 0.08 0.12 enet 5 0.09 1.7e-05 -4.9 -5.3 1.4e-07 0.97 0.02 0.97 FALSE
4 GTEx Breast Mammary Tissue (Female) KIAA1143 0.11 0.00 lasso 8 0.06 9.2e-03 -4.1 -5.5 3.1e-08 0.83 0.04 0.61 TRUE
5 GTEx Ovary KIAA1143 0.24 0.26 lasso 5 0.19 1.7e-05 -5.1 -5.1 2.9e-07 0.97 0.02 0.97 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic KIAA1143 0.15 0.16 lasso 5 0.13 1.0e-07 -5.3 -5.2 2.6e-07 0.98 0.02 0.98 FALSE
7 GTEx Skin Sun Exposed Lower leg KIAA1143 0.16 0.16 lasso 7 0.16 2.0e-13 -5.1 -5.1 2.7e-07 0.97 0.02 0.98 FALSE
8 The Cancer Genome Atlas Bladder Urothelial Carcinoma KIAA1143 0.03 0.01 blup 28 0.01 1.9e-02 -5.1 -5.3 1.4e-07 0.94 0.01 0.72 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma KIAA1143 0.01 0.01 enet 8 0.01 1.3e-03 -5.3 -5.5 4.0e-08 0.98 0.01 0.94 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma KIAA1143 0.10 0.10 lasso 2 0.10 1.8e-06 -5.3 -5.2 2.3e-07 0.96 0.01 0.98 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma KIAA1143 0.03 0.00 blup 34 0.00 1.1e-01 -5.1 -5.5 4.3e-08 0.96 0.01 0.60 FALSE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma KIAA1143 0.14 0.10 enet 15 0.09 1.3e-04 -5.3 -5.2 2.5e-07 0.97 0.01 0.98 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma KIAA1143 0.05 0.07 lasso 6 0.06 9.1e-07 -5.1 -5.2 1.7e-07 0.96 0.01 0.99 FALSE