[Hub]/) : Traits : Lung FEV1/FVC ratio :

chr4:76,342,004-77,927,345

Best TWAS P=1.24e-08 · Best GWAS P=1.14e-07 conditioned to 0.00659

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Colon Sigmoid NUP54 0.27 0.18 enet 42 0.22 3.1e-08 3.9 5.7 1.2e-08 0.53 0.05 0.94 TRUE
2 GTEx Heart Atrial Appendage FAM47E-STBD1 0.11 0.02 lasso 4 0.00 3.0e-01 5.1 5.2 2.1e-07 0.73 0.03 0.70 FALSE
3 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma NUP54 0.09 0.07 lasso 2 0.08 4.0e-04 5.0 5.1 2.8e-07 0.91 0.01 0.86 FALSE