Best TWAS P=1.24e-08 · Best GWAS P=1.14e-07 conditioned to 0.00659
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Sigmoid | NUP54 | 0.27 | 0.18 | enet | 42 | 0.22 | 3.1e-08 | 3.9 | 5.7 | 1.2e-08 | 0.53 | 0.05 | 0.94 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | FAM47E-STBD1 | 0.11 | 0.02 | lasso | 4 | 0.00 | 3.0e-01 | 5.1 | 5.2 | 2.1e-07 | 0.73 | 0.03 | 0.70 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | NUP54 | 0.09 | 0.07 | lasso | 2 | 0.08 | 4.0e-04 | 5.0 | 5.1 | 2.8e-07 | 0.91 | 0.01 | 0.86 | FALSE |