TWAS
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Genes
Traits
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Traits
:
Lung FEV1/FVC ratio
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chr4:78,734,563-79,701,528
Best TWAS P=2.08e-11 · Best GWAS P=4.09e-16 conditioned to 4.77e-08
78.8M
79M
79.2M
79.4M
79.6M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Prostate Adenocarcinoma
FRAS1
0.04
0.02
lasso
6
0.03
0.00052
6.7
6.7
2.1e-11
0.52
0.18
0.06
TRUE