TWAS
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Usage
Models
Genes
Traits
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Traits
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Lung FEV1/FVC ratio
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chr5:33,958,959-35,523,639
Best TWAS P=4.96e-11 · Best GWAS P=1.32e-10 conditioned to 0.277
34M
34.2M
34.4M
34.6M
34.8M
35M
35.2M
35.4M
35.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Skin Sun Exposed Lower leg
RAI14
0.21
0.17
lasso
6
0.16
2.4e-13
-6.2
6.6
5e-11
-0.91
0.01
0.99
TRUE