Best TWAS P=1.66e-10 · Best GWAS P=3.98e-11 conditioned to 0.0444
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | DNAH5 | 0.17 | 0.07 | enet | 32 | 0.13 | 1.8e-16 | 5.0 | -5.3 | 1.4e-07 | -0.80 | 0.18 | 0.82 | FALSE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | DNAH5 | 0.09 | 0.07 | lasso | 3 | 0.05 | 8.3e-07 | 6.2 | -6.1 | 1.1e-09 | -0.95 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | DNAH5 | 0.11 | 0.08 | enet | 8 | 0.09 | 6.1e-10 | 6.2 | -6.4 | 1.7e-10 | -0.89 | 0.00 | 1.00 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DNAH5 | 0.08 | 0.09 | lasso | 4 | 0.07 | 2.0e-07 | 6.2 | -6.0 | 1.8e-09 | -0.95 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | DNAH5 | 0.14 | 0.06 | enet | 17 | 0.08 | 1.6e-08 | 6.5 | -5.6 | 2.7e-08 | -0.86 | 0.00 | 1.00 | FALSE |