TWAS
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Traits
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Lung FEV1/FVC ratio
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chr5:42,831,514-44,249,820
Best TWAS P=4.73e-08 · Best GWAS P=4.06e-11 conditioned to 2.93e-05
42.8M
43M
43.2M
43.4M
43.6M
43.8M
44M
44.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Frontal Cortex BA9
PAIP1
0.13
-0.01
enet
25
0.02
0.11
3.8
-5.5
4.7e-08
0.59
0.03
0.61
TRUE