Best TWAS P=5.57e-09 · Best GWAS P=1.25e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | EMB | 0.05 | 0.05 | lasso | 7 | 0.05 | 1.3e-04 | -5.6 | 5.7 | 1.5e-08 | -1.00 | 0.03 | 0.96 | FALSE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | EMB | 0.04 | 0.04 | blup | 33 | 0.03 | 1.4e-04 | -5.6 | 5.8 | 5.6e-09 | -1.00 | 0.01 | 0.98 | TRUE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | EMB | 0.04 | 0.03 | enet | 20 | 0.04 | 5.6e-05 | -5.6 | 5.3 | 8.6e-08 | -0.86 | 0.01 | 0.98 | FALSE |