TWAS
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Traits
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Lung FEV1/FVC ratio
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chr5:80,873,851-82,264,985
Best TWAS P=2.09e-07 · Best GWAS P=5.63e-07 conditioned to 1.37e-06
80.8M
81M
81.2M
81.4M
81.6M
81.8M
82M
82.2M
0
1
2
3
4
5
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Mucosa
RPS23
0.09
0.02
lasso
5
0.05
0.00028
3.4
-5.2
2.1e-07
-0.03
0.02
0.11
TRUE