[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr5:75,812,681-78,353,059

Best TWAS P=9.53e-10 · Best GWAS P=2.45e-12 conditioned to 0.00038

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	NTR	Blood	PDE8B	0.04	0.03	lasso	2	0.03	2.7e-09	-5.9	6.1	9.5e-10	-0.89	0.04	0.96	TRUE
6	The Cancer Genome Atlas	Thyroid Carcinoma	LHFPL2	0.06	0.06	lasso	2	0.05	1.2e-05	-5.4	5.4	6.1e-08	0.01	0.01	0.98	TRUE
5	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PDE8B	0.17	0.03	lasso	6	0.02	7.1e-04	-5.9	-5.8	7.3e-09	0.72	0.11	0.43	FALSE
7	The Cancer Genome Atlas	Thyroid Carcinoma	PDE8B	0.05	0.02	blup	185	0.03	3.5e-04	-5.2	5.5	4.0e-08	-0.43	0.67	0.17	FALSE
1	GTEx	Artery Aorta	PDE8B	0.13	0.00	lasso	2	0.01	1.2e-01	-6.0	-5.4	6.5e-08	0.87	0.05	0.86	FALSE
2	GTEx	Pituitary	WDR41	0.35	0.26	enet	27	0.08	4.5e-03	-5.6	-5.4	6.7e-08	0.85	0.29	0.48	FALSE
3	GTEx	Testis	CTD-2037K23.2	0.20	0.19	lasso	2	0.18	2.7e-08	-5.4	5.4	8.0e-08	0.01	0.02	0.98	FALSE