Best TWAS P=1.83e-09 · Best GWAS P=5.04e-09 conditioned to 0.00142
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | EXOC2 | 0.33 | 0.10 | lasso | 10 | 0.09 | 1.3e-05 | -5.1 | -5.2 | 1.7e-07 | 0.42 | 0.25 | 0.71 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | EXOC2 | 0.23 | 0.16 | lasso | 4 | 0.16 | 4.0e-12 | -5.1 | -5.3 | 1.4e-07 | 0.48 | 0.18 | 0.82 | FALSE |
| 3 | METSIM | Adipose | EXOC2 | 0.10 | 0.04 | lasso | 11 | 0.06 | 9.8e-10 | -5.1 | -5.5 | 3.1e-08 | 0.54 | 0.23 | 0.77 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | EXOC2 | 0.18 | 0.03 | blup | 203 | 0.10 | 1.4e-11 | -5.1 | -6.0 | 1.8e-09 | 0.52 | 0.30 | 0.67 | TRUE |