Best TWAS P=1.27e-08 · Best GWAS P=5.97e-07 conditioned to 0.0218
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ADAM32 | 0.24 | 0.12 | blup | 349 | 0.19 | 4.4e-23 | 2.0 | 5.3 | 1.4e-07 | 0.03 | 0.01 | 0.01 | TRUE |
2 | GTEx | Adrenal Gland | RP11-90P5.2 | 0.18 | 0.18 | enet | 24 | 0.22 | 2.0e-08 | 5.0 | -5.4 | 6.0e-08 | -0.79 | 0.02 | 0.95 | FALSE |
3 | GTEx | Artery Aorta | RP11-90P5.2 | 0.17 | 0.02 | enet | 22 | 0.06 | 4.6e-04 | 4.1 | -5.7 | 1.3e-08 | -0.50 | 0.03 | 0.55 | TRUE |
4 | GTEx | Skin Sun Exposed Lower leg | WHSC1L1 | 0.06 | 0.01 | enet | 19 | 0.01 | 3.8e-02 | 4.4 | -5.2 | 1.6e-07 | -0.61 | 0.05 | 0.63 | FALSE |
5 | YFS | Blood | BAG4 | 0.01 | 0.01 | bslmm | 234 | 0.00 | 2.6e-02 | 5.0 | 5.4 | 7.4e-08 | 0.78 | 0.02 | 0.84 | FALSE |