Best TWAS P=2.05e-13 · Best GWAS P=5.12e-23 conditioned to 2.39e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Esophageal Carcinoma | FLJ12825 | 0.12 | 0.05 | blup | 59 | 0.02 | 6.9e-02 | -4.3 | 7.2 | 4.3e-13 | -0.36 | 0.03 | 0.14 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | HOXC5 | 0.02 | 0.00 | blup | 51 | 0.01 | 2.4e-02 | 5.3 | 7.0 | 1.9e-12 | -0.48 | 0.03 | 0.05 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HOXC6 | 0.03 | 0.02 | blup | 50 | 0.03 | 3.9e-04 | 5.5 | -7.3 | 2.1e-13 | 0.65 | 0.13 | 0.42 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HOXC8 | 0.03 | 0.05 | enet | 5 | 0.04 | 2.4e-05 | 5.5 | -7.0 | 1.9e-12 | 0.60 | 0.16 | 0.66 | FALSE |
| 5 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | FLJ12825 | 0.25 | 0.09 | lasso | 4 | 0.12 | 1.6e-05 | -5.0 | 5.1 | 3.0e-07 | -0.26 | 0.28 | 0.39 | FALSE |
| 6 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | HOXC10 | 0.33 | 0.02 | blup | 56 | 0.06 | 8.2e-03 | -9.9 | 5.4 | 6.4e-08 | -0.59 | 0.00 | 0.56 | TRUE |
| 7 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | FLJ12825 | 0.15 | 0.02 | lasso | 5 | 0.06 | 8.9e-03 | 5.5 | 6.9 | 5.8e-12 | -0.40 | 0.02 | 0.18 | FALSE |