[Hub]/) : Traits : Lung FVC : ← →

chr12:49,556,303-51,912,062

Best TWAS P=4.29e-12 · Best GWAS P=1.64e-11 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DIP2B	0.11	0.10	enet	16	0.13	2.6e-15	-5.5	-5.4	5.5e-08	-0.67	0.77	0.23	FALSE
2	GTEx	Adipose Subcutaneous	ATF1	0.07	0.05	enet	14	0.04	3.1e-04	5.3	6.0	2.6e-09	0.85	0.03	0.96	FALSE
3	GTEx	Adipose Visceral Omentum	CERS5	0.10	0.01	enet	11	0.01	1.3e-01	5.0	-5.8	8.6e-09	-0.71	0.07	0.56	FALSE
4	GTEx	Adrenal Gland	DIP2B	0.16	0.05	lasso	9	0.07	2.1e-03	6.0	5.3	1.1e-07	0.82	0.17	0.34	FALSE
5	GTEx	Artery Aorta	ATF1	0.26	0.29	lasso	2	0.28	1.5e-15	5.3	5.3	8.6e-08	0.78	0.88	0.12	FALSE
6	GTEx	Artery Coronary	ATF1	0.20	0.09	lasso	4	0.05	1.2e-02	5.3	5.7	9.5e-09	0.85	0.02	0.93	FALSE
7	GTEx	Artery Tibial	ATF1	0.24	0.26	lasso	7	0.25	2.7e-19	5.3	5.4	7.4e-08	0.79	0.86	0.14	FALSE
8	GTEx	Breast Mammary Tissue	ATF1	0.07	0.07	lasso	5	0.04	2.9e-03	6.1	5.9	3.6e-09	0.81	0.05	0.73	FALSE
9	GTEx	Breast Mammary Tissue (Female)	ATF1	0.04	0.03	enet	7	0.00	2.7e-01	6.1	6.7	2.6e-11	0.79	0.04	0.25	FALSE
10	GTEx	Cells Transformed fibroblasts	LIMA1	0.17	0.01	lasso	6	0.02	8.8e-03	4.9	6.0	1.7e-09	0.80	0.01	0.95	FALSE
11	GTEx	Cells Transformed fibroblasts	DIP2B	0.16	0.08	lasso	3	0.08	6.2e-07	6.7	6.5	6.9e-11	0.95	0.00	1.00	FALSE
12	GTEx	Cells Transformed fibroblasts	LARP4	0.21	0.24	lasso	6	0.22	1.4e-16	4.9	5.3	1.3e-07	0.67	0.98	0.02	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	ATF1	0.15	0.15	lasso	4	0.14	7.8e-06	5.3	5.5	4.2e-08	0.75	0.09	0.87	FALSE
14	GTEx	Esophagus Muscularis	ATF1	0.15	0.17	lasso	2	0.16	7.5e-10	5.3	5.4	7.7e-08	0.78	0.55	0.45	FALSE
15	GTEx	Lung	LARP4	0.07	0.05	enet	15	0.05	1.8e-04	5.4	5.8	5.1e-09	0.67	0.34	0.61	FALSE
16	GTEx	Muscle Skeletal	DIP2B	0.03	0.04	lasso	6	0.04	1.1e-04	5.3	5.5	4.5e-08	0.78	0.27	0.70	FALSE
17	GTEx	Muscle Skeletal	ATF1	0.09	0.06	lasso	5	0.07	5.0e-07	5.3	5.6	2.4e-08	0.80	0.07	0.92	FALSE
18	GTEx	Skin Sun Exposed Lower leg	ATF1	0.07	0.07	lasso	4	0.08	6.1e-07	6.1	5.9	2.9e-09	0.83	0.19	0.81	FALSE
19	GTEx	Skin Sun Exposed Lower leg	CERS5	0.09	0.06	lasso	4	0.07	9.4e-07	4.9	-5.2	2.1e-07	-0.76	0.33	0.67	FALSE
20	GTEx	Stomach	DIP2B	0.09	0.09	lasso	5	0.07	4.1e-04	6.7	6.7	2.3e-11	0.99	0.01	0.96	FALSE
21	GTEx	Whole Blood	DIP2B	0.12	0.08	lasso	4	0.08	5.7e-08	6.7	6.7	1.7e-11	0.99	0.00	1.00	FALSE
22	NTR	Blood	BCDIN3D	0.02	0.00	blup	331	0.00	8.2e-03	4.0	-5.2	2.5e-07	-0.24	0.03	0.04	TRUE
23	YFS	Blood	ATF1	0.05	0.07	lasso	9	0.07	2.0e-21	-5.1	-5.6	1.9e-08	-0.53	0.96	0.04	FALSE
24	YFS	Blood	DIP2B	0.36	0.27	bslmm	385	0.28	2.8e-90	6.7	-6.9	4.3e-12	-0.99	0.00	1.00	TRUE
25	YFS	Blood	LIMA1	0.04	0.06	enet	31	0.06	3.5e-19	5.2	5.9	3.9e-09	0.74	0.97	0.03	FALSE
26	The Cancer Genome Atlas	Colon Adenocarcinoma	ATF1	0.10	0.05	enet	18	0.06	3.5e-04	5.4	5.8	6.1e-09	0.83	0.02	0.97	FALSE
27	The Cancer Genome Atlas	Colon Adenocarcinoma	DIP2B	0.13	0.14	lasso	2	0.12	1.3e-07	6.7	6.7	2.1e-11	0.96	0.00	1.00	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	DIP2B	0.09	0.02	enet	9	0.05	1.3e-06	6.7	6.0	2.4e-09	0.77	0.00	0.99	FALSE
29	The Cancer Genome Atlas	Testicular Germ Cell Tumors	DIP2B	0.11	0.02	blup	79	0.02	4.5e-02	6.0	6.1	1.0e-09	0.87	0.02	0.79	FALSE