Best TWAS P=1.97e-08 · Best GWAS P=5.66e-07 conditioned to 0.638
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | TMTC4 | 0.34 | 0.20 | enet | 21 | 0.26 | 1.4e-12 | 4.8 | 5.6 | 2.0e-08 | 0.92 | 0.02 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TMTC4 | 0.02 | 0.02 | enet | 8 | 0.02 | 1.1e-04 | 4.8 | 5.4 | 5.3e-08 | 0.95 | 0.02 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | TMTC4 | 0.04 | 0.03 | lasso | 3 | 0.03 | 1.5e-04 | 4.9 | 5.3 | 1.3e-07 | 0.87 | 0.02 | 0.94 | FALSE |