Best TWAS P=5.39e-10 · Best GWAS P=1.75e-12 conditioned to 0.00023
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC25A21 | 0.11 | 0.02 | blup | 345 | 0.05 | 8.8e-04 | -0.33 | -6.0 | 2.1e-09 | 0.70 | 0.07 | 0.64 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | MIPOL1 | 0.05 | 0.07 | lasso | 2 | 0.07 | 4.6e-07 | -5.63 | -5.6 | 1.8e-08 | 0.61 | 0.02 | 0.98 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | SLC25A21 | 0.15 | 0.12 | blup | 353 | 0.11 | 5.2e-11 | -5.20 | -6.2 | 5.4e-10 | 0.73 | 0.38 | 0.62 | TRUE |