Best TWAS P=1.49e-08 · Best GWAS P=8.38e-09 conditioned to 0.000174
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | METTL22 | 0.73 | 0.32 | enet | 79 | 0.32 | 2.4e-10 | -5.2 | 5.7 | 1.5e-08 | -0.41 | 0.06 | 0.94 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | METTL22 | 0.05 | 0.06 | lasso | 4 | 0.06 | 9.0e-08 | -5.3 | 5.5 | 5.1e-08 | -0.24 | 0.03 | 0.96 | FALSE |