Best TWAS P=1.14e-09 · Best GWAS P=4.09e-09 conditioned to 0.197
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | CD55 | 0.16 | 0.08 | lasso | 9 | 0.06 | 3.9e-04 | -5.4 | 5.4 | 6.2e-08 | -0.93 | 0.08 | 0.91 | FALSE |
| 2 | GTEx | Esophagus Muscularis | CD55 | 0.25 | 0.12 | enet | 15 | 0.06 | 2.1e-04 | 5.6 | 5.3 | 1.1e-07 | -0.48 | 0.05 | 0.95 | FALSE |
| 3 | GTEx | Spleen | CD55 | 0.19 | 0.18 | lasso | 5 | 0.16 | 8.2e-05 | -5.4 | 5.2 | 2.1e-07 | -0.92 | 0.06 | 0.75 | FALSE |
| 4 | GTEx | Thyroid | CD55 | 0.07 | 0.05 | lasso | 4 | 0.07 | 7.2e-06 | -5.4 | 6.1 | 1.1e-09 | -0.86 | 0.13 | 0.86 | TRUE |
| 5 | GTEx | Whole Blood | CD55 | 0.08 | 0.09 | enet | 12 | 0.10 | 6.2e-10 | -5.8 | 5.3 | 1.2e-07 | -0.93 | 0.04 | 0.96 | FALSE |
| 6 | NTR | Blood | CD55 | 0.11 | 0.18 | lasso | 3 | 0.18 | 1.5e-55 | -5.4 | 5.8 | 8.1e-09 | -0.93 | 0.15 | 0.85 | FALSE |
| 7 | YFS | Blood | CD55 | 0.11 | 0.19 | lasso | 18 | 0.19 | 2.6e-59 | -5.5 | 5.2 | 2.4e-07 | -0.91 | 0.13 | 0.87 | FALSE |