Hub : Genes

CD55

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2600 0.0570 1.9e-09 0.106 0.099 0.115 0.111 0.113 8.3e-13 4.4e-12 7.0e-14 2.3e-13 1.2e-13
2 GTEx Adipose Visceral Omentum 0.1600 0.0590 1.3e-04 0.082 NA 0.042 NA 0.062 5.0e-05 NA 3.1e-03 NA 3.9e-04
3 GTEx Brain Cerebellum 0.1730 0.0700 4.6e-03 0.109 NA 0.058 NA 0.083 4.1e-04 NA 8.5e-03 NA 1.9e-03
4 GTEx Cells Transformed fibroblasts 0.0680 0.0280 2.4e-03 0.022 NA -0.004 NA 0.004 8.3e-03 NA 9.7e-01 NA 1.6e-01
5 GTEx Esophagus Muscularis 0.2550 0.0710 8.6e-07 0.122 NA 0.058 NA 0.057 7.4e-08 NA 2.1e-04 NA 2.2e-04
6 GTEx Spleen 0.1870 0.0750 2.2e-03 0.177 NA 0.052 NA 0.156 2.7e-05 NA 1.9e-02 NA 8.2e-05
7 GTEx Thyroid 0.0680 0.0280 1.9e-03 0.052 NA 0.058 NA 0.067 7.1e-05 NA 2.9e-05 NA 7.2e-06
8 GTEx Uterus 0.3270 0.1140 1.1e-03 0.007 NA -0.014 NA 0.031 2.3e-01 NA 8.3e-01 NA 7.9e-02
9 GTEx Whole Blood 0.0820 0.0250 2.1e-06 0.085 NA 0.105 NA 0.095 2.7e-08 NA 6.2e-10 NA 4.9e-09
10 METSIM Adipose 0.0749 0.0244 7.4e-08 0.051 0.061 0.037 0.059 0.036 4.2e-08 1.7e-09 2.5e-06 3.6e-09 3.6e-06
11 NTR Blood 0.1094 0.0205 0.0e+00 0.175 0.166 0.175 0.175 0.179 3.9e-54 3.3e-51 4.9e-54 3.6e-54 1.5e-55
12 YFS Blood 0.1125 0.0208 0.0e+00 0.188 0.172 0.186 0.187 0.188 2.6e-59 9.0e-54 1.5e-58 5.7e-59 2.6e-59
13 TCGA Prostate Adenocarcinoma 0.2393 0.0739 0.0e+00 0.237 0.214 0.213 NA 0.233 1.5e-24 5.1e-22 6.1e-22 NA 4.1e-24
14 TCGA Thyroid Carcinoma 0.1110 0.0420 3.4e-13 0.115 0.141 0.131 NA 0.143 2.7e-11 1.3e-13 1.1e-12 NA 8.6e-14

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.4 0.6 3.5 0.3 -0.7 0.7 -0.4 -1.0 -0.6 -1.2 -0.3 -0.2 -1.9 -0.7 -0.7 0.2 -0.1
Bipolar Disorder or Schizophrenia 0.2 0.4 2.0 1.2 -0.0 0.1 -0.6 -0.2 0.0 -0.7 -0.3 0.0 -1.4 -0.2 0.1 0.9 0.8
Depressed Affect (Nagel 2018) 0.1 0.1 0.4 -0.0 -0.4 0.3 0.2 -0.3 -0.3 -0.6 -0.6 -0.5 -0.3 -0.4 -0.5 -0.1 -0.3
Depression (Nagel 2018) 0.1 0.2 0.5 0.5 0.6 -0.6 -0.1 -0.1 0.5 0.4 0.2 0.6 0.3 0.5 0.5 0.4 0.7
Intelligence (Savage-Jansen 2018) 0.3 0.9 3.0 -0.8 0.5 -0.4 1.7 1.3 0.7 0.8 1.3 0.2 0.1 0.8 0.3 -1.4 -1.1
Neuroticism (Nagel 2018) 0.1 0.2 0.8 -0.2 0.6 -0.6 0.4 -0.1 0.7 0.5 0.3 0.9 0.5 0.4 0.5 0.3 0.2
Schizophrenia (2018) 0.2 0.4 1.5 1.2 0.5 -0.5 -0.5 0.5 0.6 0.1 -0.1 0.2 -0.3 0.3 0.7 1.0 1.2
Schizophrenia vs Biploar Disorder 1.5 2.0 4.3 -0.8 1.7 -1.7 -0.7 -0.1 1.7 1.2 0.3 1.8 0.7 1.4 1.8 1.9 2.1
Worry (Nagel 2018) 0.8 1.7 3.0 0.6 1.6 -1.5 0.6 0.2 1.7 1.6 1.1 1.7 1.3 1.6 1.6 0.7 1.1
Alzheimer’s Disease (in mother) 5.2 6.1 13.5 -0.2 3.0 -2.8 -0.1 0.7 2.9 2.3 0.3 3.7 -0.2 2.8 3.1 3.2 3.6
Alzheimer’s Disease (in father) 1.6 1.8 3.4 1.8 -1.1 1.7 -1.2 -1.7 -1.6 -1.1 -1.4 -0.5 -1.4 -1.3 -1.1 1.5 0.3
Alzheimer’s Disease (including proxy) 3.6 5.2 20.9 0.8 1.9 -1.3 -1.6 -0.7 1.4 1.0 -1.1 3.5 -2.0 1.5 2.2 4.6 4.0
Crohns Disease (2017) 0.3 0.6 1.8 0.5 0.8 -0.9 0.2 -0.2 0.8 1.1 0.5 1.4 0.5 0.8 1.0 0.7 0.9
Irritable Bowel Disease (IBD) 0.4 0.9 4.6 2.1 0.6 -0.7 0.9 0.2 0.6 1.1 1.1 1.0 1.3 0.7 0.6 -0.4 0.2
Ulcerative Colitis (UC) 0.4 0.7 6.2 2.5 -0.2 0.0 0.5 0.0 -0.1 0.1 0.8 -0.0 1.0 -0.1 -0.3 -0.9 -0.5
Major Depression (MDD) 1.8 2.2 3.4 1.1 -1.7 1.7 -1.5 -1.8 -1.8 -1.7 -1.6 -1.5 -1.7 -1.7 -1.4 0.5 -0.0
Reaction Time 1.4 2.6 5.0 0.6 1.9 -2.1 0.2 -0.8 2.0 1.8 1.1 1.9 1.0 1.8 2.0 1.5 2.2
Verbal and Numeric Reasoning (VNR) 0.4 0.9 3.3 -1.1 -0.8 1.0 1.2 0.4 -0.6 -0.5 0.3 -1.0 -0.5 -0.6 -1.0 -1.5 -1.8
Breast Cancer 1.2 2.9 5.3 0.8 -2.0 2.1 -1.9 -1.4 -1.8 -2.3 -1.7 -1.8 -1.9 -2.1 -1.8 0.5 -0.4
Ovarian Cancer 0.2 0.3 1.7 1.3 -0.2 -0.2 -0.9 -0.7 -0.1 -0.4 0.4 -0.2 -0.4 -0.3 -0.2 -0.5 -0.2
Prostate Cancer 0.2 0.3 2.6 -0.2 -0.3 0.2 -0.3 -0.5 -0.3 -0.6 -0.8 -0.5 -1.6 -0.4 -0.2 0.3 0.1
Age at First Birth 0.5 0.7 2.2 -0.1 0.8 -0.9 -0.3 -1.5 0.8 1.1 0.2 0.9 -0.2 0.7 0.8 1.0 1.0
Bipolar Disorder (2011) 1.0 1.0 3.3 1.0 -0.6 0.5 -1.8 -1.8 -0.6 -0.8 -1.0 -0.4 -1.3 -0.7 -0.3 1.1 0.7
Body Mass Index (BMI) (2010) 0.7 1.0 3.0 0.3 -0.9 1.0 -1.2 -1.4 -1.2 -0.8 -1.7 -1.1 -0.6 -1.1 -0.7 0.5 0.1
Coronary Artery Disease (CAD) 3.9 4.7 8.2 -1.2 -2.7 2.7 -0.4 -0.8 -2.7 -2.0 -1.2 -2.8 -1.3 -2.6 -2.9 -1.7 -2.9
Crohns Disease (2012) 0.3 0.5 1.0 0.1 0.7 -0.9 0.3 0.8 0.7 1.0 0.2 0.7 0.3 0.8 1.0 0.7 0.8
Mean Putamen Volume 0.1 0.1 0.5 0.7 0.1 -0.1 -0.6 -0.2 -0.0 0.1 0.3 -0.0 -0.6 0.1 0.2 -0.1 0.1
Fasting Glucose 0.5 0.6 2.0 1.2 -0.6 0.5 -0.8 -1.0 -0.7 -0.8 -0.9 -0.7 -1.4 -0.2 -0.3 0.1 0.0
HbA1C 1.3 1.5 5.8 0.4 -1.2 0.8 1.4 -0.4 -0.9 -0.7 0.9 -1.4 -0.0 -0.2 -1.2 -2.4 -2.1
HDL Cholesterol 0.2 0.3 0.9 0.7 0.8 -0.4 0.8 1.0 0.6 0.4 0.2 0.5 0.6 0.7 0.5 -0.1 -0.0
LDL Cholesterol 0.1 0.2 0.7 0.5 -0.0 0.2 0.8 0.4 0.3 -0.3 0.7 -0.5 0.3 -0.2 -0.2 -0.3 -0.4
Lupus 0.2 0.4 2.2 1.5 -0.1 0.0 0.3 1.4 -0.0 0.2 0.4 -0.2 -0.5 -0.1 -0.1 -0.6 -0.3
Neuroticism (2016) 0.7 1.0 2.4 -1.4 -0.7 1.0 0.8 1.0 -0.8 -0.2 -0.8 -1.4 0.6 -0.6 -1.0 -1.3 -1.5
Primary Biliary Cirrhosis 0.9 1.3 2.4 -0.7 1.3 -1.3 0.1 1.0 1.1 1.3 -0.4 1.0 -1.2 1.2 1.4 1.1 1.6
Rheumatoid Arthritis 0.4 0.6 3.7 -0.8 0.0 -0.0 0.3 1.6 -0.0 -0.4 -0.3 0.6 -1.9 -0.1 0.1 0.3 0.3
Schizophrenia (2014) 0.3 0.7 2.4 1.4 0.7 -0.5 -0.7 0.2 0.5 0.3 -0.2 0.9 -0.6 0.6 0.9 1.4 1.5
Triglycerides 0.4 0.6 4.0 -2.0 0.4 -0.4 0.8 1.5 0.6 0.5 0.4 0.5 0.7 0.5 0.4 -0.0 -0.1
Type 2 Diabetes (T2D) (2012) 1.1 1.3 2.4 1.3 1.4 -1.4 0.2 0.1 1.3 1.3 0.7 0.9 0.8 1.3 1.5 1.1 1.5
Ulcerative Colitis 0.2 0.3 1.7 1.3 0.5 -0.5 0.5 0.4 0.4 0.7 0.2 0.6 0.3 0.5 0.3 -0.3 0.3
Blood Eosinophil Count 0.7 5.1 14.4 1.5 0.3 -0.3 3.7 2.7 0.6 0.4 3.6 -0.4 3.1 0.8 -0.3 -3.8 -3.0
Blood Platelet Count 0.1 1.0 3.1 1.6 0.6 -1.0 -1.2 -0.7 0.9 -0.2 0.4 0.7 1.8 0.7 0.8 1.0 1.3
Blood Red Count 0.4 3.9 11.7 -1.8 -1.4 1.3 -2.6 -3.2 -1.6 -1.4 -3.4 -1.4 -2.5 -1.8 -1.1 1.3 0.8
Blood White Count 0.5 4.0 32.3 2.0 0.5 -1.1 1.6 0.2 1.0 0.6 2.6 -0.1 5.7 0.8 0.2 -2.3 -1.3
Heel T-Score 0.5 3.6 12.7 0.2 0.1 -0.0 3.6 2.2 0.3 0.8 3.2 -0.5 1.7 0.6 -0.4 -3.2 -2.9
BMI 0.3 1.5 5.9 0.8 0.3 -0.4 -2.4 -1.5 -0.0 0.2 -1.9 -0.1 0.5 0.0 0.6 1.8 2.0
Height 0.3 5.9 18.7 -1.1 -2.3 2.5 1.3 1.5 -2.4 -1.6 -0.1 -3.0 1.9 -1.9 -2.7 -4.0 -4.3
Waist Hip Ratio (WHR) 0.4 1.6 7.2 0.5 -1.0 1.0 1.1 0.6 -0.9 -0.4 0.8 -1.4 0.1 -0.8 -1.2 -2.7 -2.3
Systolic Blood Pressure 0.6 3.0 8.4 -1.9 1.1 -1.2 -2.0 -2.6 1.1 -0.2 -1.4 1.3 -1.3 0.6 1.3 2.8 2.9
Smoking Status 0.6 1.5 7.1 2.7 0.7 -0.7 -0.8 -1.4 0.8 0.2 0.6 1.8 -0.5 0.5 0.8 1.6 1.5
Allergy or Eczema 0.2 0.5 2.2 1.5 0.2 -0.3 -0.7 -0.6 0.2 0.5 0.0 0.8 -1.4 0.1 0.3 0.8 0.7
Cardiovascular Disease 0.3 1.1 7.5 2.7 0.5 -0.8 -0.5 -0.9 0.7 -0.1 0.7 0.9 0.9 0.5 0.7 0.9 1.2
Hypothyroidism (self reported) 1.2 2.7 8.5 -0.0 -0.2 0.4 -2.8 -1.9 -0.7 -0.6 -2.9 0.4 -2.7 -0.8 -0.1 2.2 1.9
Respiratory disease 1.9 4.2 13.5 2.0 -0.8 0.6 -3.7 -3.0 -0.6 -1.7 -2.0 -0.5 -2.9 -1.2 -0.3 3.0 2.2
Type 2 Diabetes (T2D) (2018) 1.0 1.9 4.4 2.1 -1.2 1.6 0.4 1.4 -1.5 -0.9 0.4 -1.6 0.6 -1.0 -1.3 -1.8 -1.9
Lung FEV1/FVC ratio 0.1 0.6 3.8 -1.4 0.5 -0.4 0.4 1.9 0.3 1.3 -0.3 0.1 -0.6 0.5 0.4 -0.3 -0.0
Lung FVC 4.2 21.4 37.1 -0.4 5.4 -4.9 5.1 5.3 5.2 6.1 4.7 5.3 3.7 5.8 5.2 -0.0 2.0
Neuroticism 0.1 0.2 0.8 0.6 -0.3 0.1 -0.5 -0.9 -0.0 -0.7 -0.3 -0.1 -0.1 -0.3 -0.2 0.5 0.1
Chronotype (morning person) 1.0 2.3 7.3 0.8 0.0 -0.4 2.5 2.0 0.5 0.6 2.7 -0.7 1.7 0.5 -0.1 -2.3 -2.1
Hair Pigment 0.0 1.4 3.5 1.9 -1.3 1.5 -1.3 -1.1 -1.6 -1.1 -0.9 -0.8 -0.2 -1.5 -1.4 -0.1 -0.6
Tanning 0.1 1.2 2.9 0.8 1.2 -1.6 -0.7 -0.3 1.4 0.7 -0.1 0.8 -0.4 1.1 1.4 1.3 1.7
Hand grip strength (left) 0.6 1.5 2.9 -0.1 1.5 -1.7 0.9 1.3 1.5 1.4 1.0 1.0 1.7 1.5 1.4 0.1 0.9
Number of treatments/medications taken 0.9 1.5 4.1 1.1 1.4 -1.6 -0.5 0.4 1.3 1.2 0.1 1.2 1.1 1.2 1.4 1.4 2.0
Average weekly spirits intake 1.0 1.2 5.8 -0.9 -0.3 0.4 -2.0 -1.4 -0.6 -1.0 -2.4 -0.2 -0.2 -0.6 -0.2 1.0 1.1
Sensitivity / hurt feelings 0.1 0.1 0.6 0.2 -0.2 -0.0 0.0 -0.3 -0.1 -0.2 0.4 -0.1 0.6 -0.1 -0.3 -0.8 -0.6
Frequency of depressed mood in last 2 weeks 0.3 0.4 1.8 -0.6 0.2 -0.0 -0.9 -0.2 0.1 0.1 -0.8 0.5 -0.2 0.2 0.3 1.4 1.0
Hearing difficulty/problems: Yes 0.9 1.3 3.8 0.3 1.0 -0.7 -1.0 -0.0 0.6 0.5 -0.7 1.7 -1.9 0.6 1.0 1.8 2.0
Relative age of first facial hair 0.3 0.7 2.8 0.7 0.5 -0.5 -1.2 -1.7 0.5 0.3 -0.1 0.7 -0.3 0.4 0.7 1.2 1.3
Other serious medical condition/disability diagnosed by doctor 2.0 2.6 8.2 -0.7 1.1 -1.1 -1.9 -1.3 1.0 0.5 -1.2 1.8 -1.8 0.8 1.4 2.9 2.8
Ever used hormone-replacement therapy (HRT) 1.9 2.4 6.0 -0.1 1.9 -1.5 0.6 1.3 1.6 1.5 0.7 2.5 0.9 2.0 2.1 1.5 1.7
Ever had hysterectomy (womb removed) 0.3 0.3 0.6 -0.5 0.5 -0.3 -0.2 0.7 0.3 0.6 -0.7 0.4 -0.1 0.5 0.6 0.8 0.8
Systolic blood pressure, automated reading 1.3 3.8 10.7 -1.7 1.2 -1.4 -2.5 -2.5 1.1 0.7 -2.1 1.5 -1.4 0.8 1.6 3.0 3.3
Eye problems/disorders: Diabetes related eye disease 0.7 0.8 3.0 1.7 -0.9 0.9 -0.6 -0.5 -1.1 -0.6 -0.2 -1.4 0.1 -0.8 -0.8 -0.5 -0.6
Angina 1.6 2.2 9.7 0.7 0.1 0.0 2.5 3.1 0.3 0.8 2.3 0.0 0.1 0.4 -0.2 -2.2 -1.7
Medication for hormone replacement therapy 1.0 1.1 5.7 -2.4 -0.9 1.3 -0.3 0.6 -1.1 -1.2 -1.3 -0.7 -0.5 -0.8 -0.9 0.3 -0.5
Vitamin and mineral supplements 0.2 0.3 1.4 -1.2 0.1 0.2 -0.6 0.5 -0.2 0.5 -1.1 0.0 0.4 0.1 0.3 0.6 0.6
Supplements: Zinc 1.0 1.1 3.0 0.8 1.0 -1.1 -0.4 -0.6 1.2 0.4 0.3 1.3 0.6 1.0 1.3 1.7 1.7
Medication: Co-codamol 1.9 2.2 6.4 1.4 1.4 -1.5 -1.1 0.8 1.4 1.1 -0.3 1.9 0.0 1.2 1.7 2.1 2.5
Medication: Metformin 0.2 0.3 2.0 1.4 -0.3 0.1 -0.5 0.7 -0.3 -0.0 0.1 -0.7 0.1 -0.3 -0.2 -0.2 0.0
Diabetes (father) 0.6 0.8 3.1 1.4 -0.1 -0.1 0.5 0.9 -0.3 0.8 0.5 -0.9 1.8 -0.1 -0.1 -1.5 -0.9
Diabetes (mother) 1.0 1.3 3.0 -1.6 1.1 -1.1 1.1 1.7 1.1 1.4 0.4 0.2 1.7 1.2 1.1 -0.5 0.0
Severe depression (siblings) 0.7 0.8 3.3 1.8 -0.9 1.1 -0.7 0.0 -0.8 -0.9 0.2 -0.7 -1.1 -0.9 -0.8 0.2 -0.4
Pack years adult smoking proportion 0.4 0.6 1.9 0.2 0.7 -0.7 -0.8 -0.9 0.8 0.5 -0.4 0.2 -0.4 0.5 0.8 1.4 1.4
Impedance of leg (right) 0.3 1.6 5.7 0.4 1.1 -1.4 1.8 0.4 1.5 1.1 2.4 1.2 1.4 1.4 1.0 -0.9 -0.3
Leg fat-free mass (left) 0.3 1.3 4.1 -0.3 -1.1 1.3 -0.5 0.6 -1.4 -0.8 -1.6 -2.0 0.8 -1.1 -1.2 -1.0 -1.1
Trunk fat percentage 0.1 0.5 1.9 1.4 -0.0 -0.2 -0.9 -0.4 -0.1 0.3 -1.0 -0.8 1.3 0.0 0.1 0.2 0.6
Hand grip strength (right) 0.4 1.1 3.0 -1.1 0.5 -0.5 1.7 1.7 0.6 0.9 1.1 -0.1 1.7 0.7 0.3 -1.2 -0.8
Townsend deprivation index at recruitment 2.0 2.7 4.7 0.1 2.0 -1.8 0.2 0.7 2.2 1.7 1.6 2.0 -0.5 1.9 2.2 2.0 2.1
Current tobacco smoking 1.0 1.6 4.0 1.4 1.0 -1.2 -1.1 -1.4 1.0 0.4 -0.0 1.5 -1.5 0.7 1.1 1.7 2.0
Average weekly fortified wine intake 0.3 0.4 3.3 -1.8 -0.0 -0.2 0.3 0.7 0.1 0.1 0.0 0.4 -0.9 -0.0 -0.2 -0.4 -0.2
Maternal smoking around birth 0.2 0.3 1.8 -1.3 0.5 -0.6 0.3 0.6 0.7 0.3 -0.0 0.3 0.3 0.5 0.5 0.3 0.3
Fed-up feelings 0.5 0.9 2.8 -0.5 1.0 -0.9 -0.5 -0.9 1.1 0.5 -0.4 1.1 0.0 0.9 1.0 1.7 1.4
Frequency of unenthusiasm / disinterest in last 2 weeks 2.2 2.9 4.9 -0.3 2.2 -2.1 0.8 1.3 2.2 1.7 1.1 2.1 1.3 2.2 2.1 1.0 1.8
Relative age voice broke 0.8 1.3 2.0 1.3 1.2 -1.4 0.0 -1.1 1.4 1.0 1.0 1.1 0.4 1.3 1.3 0.8 1.4
Taking other prescription medications 2.4 3.6 11.6 3.4 1.6 -1.7 -1.5 -0.6 1.4 1.2 -0.3 2.0 0.1 1.3 1.9 2.8 3.3
Age when periods started (menarche) 0.8 1.9 4.5 -1.3 1.7 -1.8 0.5 0.9 1.8 1.6 1.1 2.1 -0.2 1.7 1.6 0.3 0.9
Bilateral oophorectomy (both ovaries removed) 1.4 1.7 3.1 -1.8 1.6 -1.3 0.2 1.0 1.2 1.7 -0.2 1.5 0.2 1.5 1.6 1.2 1.4
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.1 0.3 -0.3 -0.3 0.5 0.6 -0.1 -0.5 -0.3 -0.4 -0.4 0.1 -0.2 -0.4 -0.5 -0.5
Tinnitus: Yes, but not now, but have in the past 0.6 0.7 2.0 0.6 -0.5 0.5 1.2 1.1 -0.3 -0.3 1.4 -0.3 -0.1 -0.3 -0.6 -1.2 -1.4
Qualifications: CSEs or equivalent 0.6 0.8 3.0 0.3 -0.5 0.4 -0.1 1.7 -0.7 -0.1 -0.6 -1.4 1.2 -0.4 -0.4 -1.3 -0.9
Serious illness, injury or assault to yourself 0.1 0.2 0.6 0.8 0.3 -0.6 -0.5 0.0 0.3 0.3 -0.2 -0.6 0.2 0.2 0.4 -0.2 0.2
High blood pressure 0.8 2.2 4.8 1.7 1.6 -1.7 -0.4 -0.3 1.6 1.0 0.3 1.8 1.2 1.5 1.8 1.6 2.2
Hayfever, allergic rhinitis or eczema 0.7 1.6 3.7 0.6 1.5 -1.5 -0.3 -0.2 1.4 1.8 0.5 1.9 -0.8 1.4 1.5 1.2 1.5
Multivitamins +/- minerals 0.5 0.6 3.1 0.5 0.6 -0.8 1.2 0.6 0.9 0.1 1.8 0.9 0.1 0.7 0.5 -0.5 -0.4
Stomach or abdominal pain in last month 0.6 0.7 6.0 2.4 -0.4 0.3 -0.2 -1.1 -0.1 -0.6 1.0 -0.1 -0.8 -0.2 -0.3 0.1 -0.3
Supplements: Glucosamine 0.1 0.1 0.4 0.5 0.2 -0.3 0.2 0.4 0.2 0.0 0.6 0.5 0.6 0.4 0.3 -0.2 -0.0
Diverticular disease/diverticulitis (self-reported) 1.6 1.9 5.4 1.9 0.1 -0.1 2.1 1.3 0.2 0.5 2.3 -0.2 1.7 0.3 -0.2 -2.3 -1.9
Medication: Atenolol 0.4 0.5 1.8 1.3 -0.6 0.6 0.4 0.6 -0.9 -0.6 0.4 -0.5 0.3 -0.6 -0.7 -1.1 -1.0
Medication: Levothyroxine sodium 1.0 1.8 7.1 -0.8 -0.2 0.5 -1.9 -0.4 -0.5 -0.9 -2.4 0.7 -2.7 -0.5 -0.1 1.9 1.4
Sitting height 0.8 5.5 19.0 -0.4 -1.9 2.1 1.8 1.6 -2.2 -0.9 0.4 -2.9 2.3 -1.4 -2.2 -4.4 -4.2
Chronic bronchitis/emphysema (father) 0.3 0.3 0.6 -0.5 -0.6 0.8 -0.1 0.3 -0.7 -0.5 -0.3 -0.7 0.5 -0.5 -0.6 -0.5 -0.7
High blood pressure (mother) 0.3 0.5 1.1 0.9 -0.6 0.8 0.2 -0.4 -1.1 -0.2 -0.7 -0.9 0.8 -0.5 -0.6 -0.5 -0.6
Body mass index (BMI) 0.2 0.9 4.2 0.7 0.1 -0.1 -1.9 -0.4 -0.3 0.1 -2.0 -0.5 0.8 -0.1 0.3 1.2 1.4
Impedance of leg (left) 0.2 1.0 3.6 0.7 0.8 -1.2 1.3 -0.0 1.3 0.8 1.9 1.0 1.0 1.0 0.8 -0.7 -0.2
Leg predicted mass (left) 0.3 1.4 4.5 -0.4 -1.2 1.4 -0.4 0.7 -1.5 -0.8 -1.6 -2.1 0.8 -1.1 -1.2 -1.1 -1.2
Trunk fat mass 0.2 0.7 2.4 1.0 -0.4 0.2 -1.1 -0.3 -0.6 0.1 -1.5 -1.3 1.5 -0.3 -0.2 -0.2 0.2
Waist circumference 0.2 0.7 3.6 0.3 -0.2 0.1 -1.8 -0.7 -0.4 -0.0 -1.9 -0.8 0.9 -0.3 0.0 0.7 0.9
Number of incorrect matches in round 1.3 2.2 4.3 1.4 1.7 -2.0 0.3 -0.0 1.9 1.4 1.3 2.1 1.1 1.7 1.7 1.2 1.7
Past tobacco smoking 0.4 0.8 2.4 -1.5 -0.6 0.8 -0.0 0.3 -0.9 -0.2 -1.3 -1.1 -1.5 -0.7 -0.7 -0.2 -0.5
Alcohol usually taken with meals 2.1 3.3 6.8 -0.5 -2.3 2.6 -0.0 -1.0 -2.2 -2.5 -1.2 -1.8 -1.5 -2.3 -2.3 -0.7 -2.0
Nervous feelings 0.9 1.7 3.4 0.1 1.3 -1.3 1.7 0.9 1.6 1.7 1.8 1.2 1.6 1.6 1.3 -0.4 0.0
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.1 0.4 -0.1 -0.2 0.2 0.2 -0.1 -0.0 -0.2 0.7 0.1 -0.7 -0.0 -0.2 -0.1 -0.5
Hearing difficulty/problems with background noise 0.6 0.9 3.2 -1.4 0.7 -0.4 -0.4 0.1 0.8 0.3 -0.3 1.8 -1.2 0.6 0.7 1.6 1.2
Hair/balding pattern: Pattern 2 1.8 2.2 5.1 1.2 1.7 -1.9 0.8 0.2 1.9 1.4 1.5 1.6 2.3 1.9 1.8 0.0 0.8
Had menopause 3.3 4.2 8.4 -0.5 2.5 -2.2 1.5 2.1 2.4 2.3 1.7 2.9 1.4 2.5 2.5 0.9 1.6
Had other major operations 1.5 1.8 3.7 0.4 1.6 -1.4 0.7 0.0 1.5 1.5 1.0 1.9 0.5 1.8 1.8 1.2 1.5
Forced vital capacity (FVC) 1.1 4.2 13.7 -0.8 1.4 -1.0 3.7 3.4 1.3 1.9 2.8 0.8 1.8 1.8 1.0 -2.3 -1.8
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 1.4 0.3 -0.7 0.9 -0.1 -0.7 -0.9 -1.2 -0.9 -0.9 -0.7 -0.7 -0.8 -0.1 -0.3
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 1.4 0.3 -0.7 0.7 -1.2 -0.6 -0.8 -0.8 -0.9 -0.6 -1.1 -0.7 -0.7 -0.3 -0.5
Qualifications: None of the above 0.5 1.0 2.0 0.4 1.0 -1.2 1.1 1.3 1.3 1.0 1.4 0.6 0.8 1.1 0.9 -0.4 0.1
Financial difficulties in last 2 years 0.5 0.7 2.8 -1.7 0.6 -0.7 -0.7 0.6 0.4 0.7 -0.9 0.3 -1.1 0.5 0.7 0.5 0.8
Mouth/teeth dental problems 0.2 0.3 0.7 -0.3 -0.6 0.6 -0.4 -0.2 -0.6 -0.3 -0.3 -0.8 0.6 -0.6 -0.7 -0.4 -0.7
Heart attack 0.2 0.3 0.5 0.1 0.7 -0.5 -0.5 0.6 0.4 0.6 0.3 0.7 0.6 0.6 0.6 0.3 0.6
Allergy 0.6 1.4 2.7 -0.9 -1.2 1.4 1.0 0.9 -1.3 -1.1 -0.3 -1.5 0.7 -1.1 -1.3 -1.4 -1.7
Pain all over the body in last month 0.3 0.3 0.5 0.0 0.7 -0.7 0.3 -0.7 0.6 0.6 0.2 0.3 0.6 0.6 0.7 0.2 0.7
Diabetes (self-reported) 0.7 1.1 5.3 2.3 -0.6 0.7 0.1 1.4 -0.8 -0.4 0.3 -1.3 1.0 -0.5 -0.6 -1.3 -1.0
Hayfever/allergic rhinitis (self-reported) 1.2 1.6 3.0 -0.9 1.5 -1.4 1.0 1.1 1.5 1.4 0.7 1.7 0.6 1.5 1.5 0.9 1.1
Medication: Ramipril 0.1 0.1 0.3 -0.2 -0.1 0.2 -0.4 0.2 -0.0 -0.3 0.0 -0.4 -0.6 -0.0 0.0 0.2 0.1
Medication: Simvastatin 0.5 0.7 1.7 1.2 0.6 -0.6 1.0 1.1 0.7 0.7 1.3 0.2 1.1 0.8 0.5 -0.3 0.0
Fluid intelligence score 0.3 0.5 1.9 -1.4 -0.6 0.8 0.7 0.2 -0.5 -0.4 0.3 -0.4 -0.6 -0.3 -0.7 -0.9 -1.3
Illnesses of siblings 0.5 0.6 1.7 -0.8 -0.9 0.7 -0.5 -1.2 -0.7 -0.7 -0.2 -0.5 -1.3 -1.0 -0.9 -0.3 -0.7
Neuroticism score 0.4 0.8 2.1 0.6 0.8 -0.8 -0.7 -1.2 1.0 0.4 0.2 1.1 0.4 0.7 0.8 1.4 1.2
Weight 0.3 1.5 4.1 0.5 -1.2 1.2 -1.4 -0.0 -1.5 -0.8 -2.0 -2.0 1.2 -1.2 -1.1 -0.6 -0.6
Impedance of arm (right) 0.1 0.4 1.7 -0.2 -0.2 0.2 1.0 -0.1 0.1 -0.0 1.3 0.1 -0.4 -0.1 -0.4 -1.0 -1.1
Arm fat percentage (right) 0.3 1.2 4.7 1.2 -0.6 0.4 -2.2 -1.0 -0.8 -0.3 -2.1 -1.2 0.5 -0.7 -0.3 0.9 0.8
Trunk fat-free mass 0.5 2.8 6.3 -0.7 -1.9 2.1 -0.7 0.7 -2.3 -1.4 -1.8 -2.5 1.1 -1.7 -1.9 -1.6 -1.9
Hip circumference 0.3 1.1 5.3 0.2 -0.4 0.4 -2.1 -0.7 -0.8 -0.4 -2.3 -0.9 0.5 -0.6 -0.2 1.1 1.0
Time employed in main current job 2.5 2.9 8.6 0.3 1.1 -1.4 2.8 1.9 1.3 1.5 2.0 0.6 2.9 1.5 0.8 -2.2 -0.9
Alcohol intake versus 10 years previously 0.6 0.9 2.1 -1.3 1.1 -1.2 0.1 1.2 1.0 1.4 0.2 1.0 -0.4 1.0 1.2 0.1 0.7
Father’s age at death 0.5 0.6 2.9 0.3 -0.5 0.9 1.7 0.7 -0.4 -0.5 0.8 -0.4 0.1 -0.3 -0.6 -0.9 -1.4
Worrier / anxious feelings 0.2 0.3 1.3 0.2 0.5 -0.8 -0.4 -0.6 0.6 0.3 0.5 0.6 1.1 0.5 0.5 0.0 0.4
Frequency of tiredness / lethargy in last 2 weeks 1.0 1.6 3.6 -1.2 1.4 -1.3 -0.6 -0.6 1.2 1.1 -0.6 1.5 -0.7 1.2 1.6 1.7 1.9
Falls in the last year 0.2 0.3 1.5 0.2 -0.4 0.5 1.2 0.8 -0.4 -0.0 0.4 -0.1 -0.7 -0.3 -0.5 -0.4 -0.6
Hair/balding pattern: Pattern 3 0.2 0.3 1.3 -0.8 -0.1 0.3 -0.4 -0.6 -0.3 -0.6 -0.8 0.1 -1.2 -0.2 -0.3 0.5 0.3
Number of live births 1.2 1.7 3.5 0.8 -1.4 1.9 -1.0 -1.2 -1.5 -1.6 -1.1 -1.2 -1.9 -1.4 -1.3 0.2 -0.7
Forced expiratory volume in 1-second (FEV1) 1.1 3.6 12.4 -1.5 1.7 -1.2 3.0 3.5 1.5 2.1 2.1 1.1 1.3 2.0 1.3 -1.5 -1.0
Pulse rate 1.9 3.2 12.8 -0.9 2.1 -2.1 0.6 0.8 1.8 2.5 0.4 1.5 3.6 2.1 2.1 0.0 1.0
Happiness 0.4 0.4 0.8 0.8 -0.7 0.8 -0.9 -0.2 -0.8 -0.6 -0.4 -0.8 0.2 -0.7 -0.6 -0.5 -0.7
Noisy workplace 0.6 0.8 4.8 2.2 -0.8 0.6 0.6 0.7 -0.7 -0.4 0.6 -0.8 0.0 -0.7 -0.8 -0.8 -0.8
Qualifications: A levels/AS levels or equivalent 1.3 2.9 5.5 -1.6 -1.9 2.3 -1.4 -1.3 -2.2 -2.0 -2.0 -1.1 -1.6 -2.0 -2.0 0.4 -0.9
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.7 0.1 0.3 -0.2 -0.7 -0.4 0.2 0.1 -0.5 0.5 -0.8 0.2 0.4 0.9 0.8
Mouth/teeth dental problems: Dentures 0.1 0.2 0.9 -0.9 -0.5 0.3 0.3 -0.1 -0.1 -0.5 0.2 -0.1 -0.1 -0.4 -0.5 -0.4 -0.3
Asthma 0.7 1.4 4.5 2.1 -0.9 0.7 -1.7 -1.9 -0.6 -1.1 -0.7 -0.8 -1.4 -1.0 -0.6 1.1 0.6
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.3 1.1 0.7 0.2 -0.2 -0.9 -0.0 0.0 0.1 -0.2 0.7 0.0 0.0 0.2 1.1 1.0
Medication: Cholesterol lowering 0.1 0.1 0.3 -0.2 -0.4 0.4 0.3 0.5 -0.4 -0.2 -0.1 -0.3 0.2 -0.4 -0.6 -0.2 -0.2
Depression (self-reported) 1.2 1.4 4.3 -0.3 0.1 0.1 -1.6 -2.0 -0.1 -0.7 -1.5 0.7 -1.4 -0.1 0.3 2.1 1.7
Medication: Lansoprazole 0.6 0.6 1.8 1.4 0.4 -0.3 -1.0 -0.9 0.3 0.9 -0.5 0.6 -0.4 0.2 0.6 1.1 1.2
Prospective memory result 1.3 1.6 6.8 2.6 -1.2 0.9 -1.7 -1.8 -0.9 -1.1 -0.6 -1.2 -0.4 -1.3 -0.8 0.9 0.3
Lung cancer (father) 0.9 1.1 2.6 0.8 1.2 -1.1 0.1 0.9 1.0 1.3 0.1 1.6 1.2 1.1 1.2 0.7 1.1
Illnesses of mother 0.3 0.4 1.0 -0.3 -0.7 0.7 -0.9 -0.6 -0.6 -0.6 -0.8 -1.0 -0.3 -0.8 -0.6 0.1 -0.2
Forced expiratory volume in 1-second (FEV1), Best measure 1.3 4.0 13.0 -0.1 1.4 -1.0 3.3 3.6 1.3 1.9 2.7 0.9 2.0 1.8 1.0 -2.2 -1.6
Pulse wave Arterial Stiffness index 1.0 1.1 2.2 -0.8 1.3 -1.3 0.1 0.5 1.1 1.4 0.2 1.5 0.5 1.3 1.5 0.7 1.2
Impedance of arm (left) 0.1 0.4 2.2 -0.0 0.1 -0.2 1.1 0.0 0.4 0.3 1.5 0.5 -0.4 0.2 -0.0 -0.9 -0.8
Arm fat mass (right) 0.3 1.1 4.9 1.0 -0.7 0.7 -1.9 -0.6 -1.1 -0.4 -2.2 -1.3 0.8 -0.8 -0.5 0.5 0.5
Trunk predicted mass 0.5 2.7 5.8 -0.8 -1.8 2.0 -0.7 0.7 -2.2 -1.3 -1.9 -2.4 1.0 -1.7 -1.8 -1.5 -1.8
Standing height 0.6 5.6 16.7 -0.4 -2.4 2.6 1.3 1.2 -2.5 -1.7 -0.0 -3.0 1.3 -1.9 -2.7 -4.0 -4.1
Length of working week for main job 2.4 2.7 6.8 -1.1 2.0 -2.0 -0.8 0.1 1.8 1.9 -0.7 1.3 0.3 1.8 2.2 1.8 2.6
Exposure to tobacco smoke at home 0.6 0.7 1.3 -0.5 1.0 -0.9 0.9 1.1 0.9 0.9 0.4 1.0 0.1 1.0 1.0 0.0 0.4
Breastfed as a baby 0.6 0.7 1.7 -0.4 -1.0 1.1 0.2 0.1 -0.9 -0.9 -0.6 -0.9 -1.3 -0.8 -0.9 -0.8 -0.9
Tense / ‘highly strung’ 3.2 5.3 12.2 1.0 2.6 -2.3 -0.7 -1.6 2.5 2.1 0.7 3.1 0.3 2.3 2.8 3.5 3.4
Seen doctor (GP) for nerves, anxiety, tension or depression 1.7 2.7 5.4 2.3 1.8 -1.8 -0.1 0.5 1.7 1.3 1.2 1.9 1.3 1.6 1.9 1.6 2.1
Hair/balding pattern: Pattern 4 0.8 2.0 6.2 1.1 -0.5 0.2 2.1 1.7 -0.1 0.4 2.3 -0.8 1.1 -0.3 -0.9 -2.5 -2.1
Birth weight of first child 0.3 0.5 3.0 1.1 -0.7 0.4 -0.1 0.5 -0.5 -0.2 0.1 -1.7 0.3 -0.7 -0.6 -0.6 -0.6
Peak expiratory flow (PEF) 1.0 2.3 11.1 -1.9 0.9 -0.7 2.1 3.3 0.8 1.3 1.3 0.4 1.0 1.2 0.7 -1.7 -1.3
Pulse wave reflection index 0.6 0.7 3.2 -0.6 -0.7 0.8 -1.1 -0.4 -0.8 -0.7 -1.1 -0.6 -1.8 -0.8 -0.5 0.8 0.2
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.4 0.8 -0.8 0.9 0.8 0.5 -0.8 -0.5 0.6 -1.0 0.2 -0.7 -0.9 -0.9 -1.2
Loud music exposure frequency 1.1 1.2 3.7 -0.8 -0.4 0.7 -1.5 -1.7 -0.6 -0.3 -1.6 0.0 -1.9 -0.6 -0.1 1.6 1.0
Qualifications: O levels/GCSEs or equivalent 1.4 2.2 3.8 -1.5 -1.7 2.0 -1.2 -1.2 -1.8 -1.8 -2.0 -1.0 -1.2 -1.8 -1.6 0.3 -0.6
Mouth/teeth dental problems: Bleeding gums 0.9 1.1 3.5 1.8 -0.3 0.4 -1.6 -1.3 -0.3 -0.4 -1.1 -0.3 -1.9 -0.3 -0.0 1.2 1.0
Blood clot in the leg (DVT) 0.1 0.1 0.6 0.2 0.1 -0.2 -0.8 -0.1 0.1 -0.2 -0.4 -0.0 -0.3 -0.1 0.0 -0.1 0.1
Medication: Paracetamol 4.3 7.2 12.7 1.3 3.2 -3.2 2.0 2.7 3.0 3.6 2.7 2.9 2.8 3.2 2.9 0.3 1.7
Headache pain in last month 2.1 3.6 5.8 0.1 2.0 -2.4 1.8 2.3 2.4 1.9 2.4 1.7 2.1 2.3 1.8 -0.5 0.4
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 0.9 0.5 0.8 -0.9 0.4 0.2 0.9 0.7 0.7 0.6 0.7 1.0 1.0 -0.2 -0.0
Glaucoma (self-reported) 4.8 5.6 10.8 2.1 2.7 -2.8 0.9 0.8 2.8 2.7 2.1 2.8 3.3 2.6 2.6 1.1 2.1
Gout (self-reported) 0.2 0.2 1.4 1.2 -0.0 -0.0 -0.1 1.0 0.2 0.2 0.6 -0.3 0.4 0.1 0.0 0.0 0.0
Hypothyroidism/myxoedema (self-reported) 1.9 3.6 12.6 -0.9 -0.3 0.7 -2.9 -1.7 -0.8 -1.0 -3.3 0.3 -3.5 -0.8 -0.1 2.8 2.1
Medication: Amlodipine 0.5 0.7 2.2 -1.2 -0.6 0.5 -1.1 -0.7 -0.6 -0.7 -0.9 -0.9 -1.5 -0.6 -0.5 0.1 0.1
Medication: Ventolin 100micrograms inhaler 0.7 1.0 7.1 2.7 -0.6 0.3 -1.0 -1.2 -0.2 -0.9 0.5 -0.2 -0.9 -0.7 -0.5 0.6 0.3
Birth weight 0.3 0.6 2.1 -0.0 0.3 -0.2 1.1 1.4 0.3 0.8 0.9 -0.6 0.8 0.5 0.2 -1.5 -0.9
Chronic bronchitis/emphysema (mother) 0.1 0.1 1.1 1.0 0.1 -0.2 -0.5 0.1 0.3 -0.0 0.4 0.3 0.3 0.1 0.1 -0.2 0.1
High blood pressure (siblings) 0.2 0.3 2.1 1.4 0.1 0.3 0.2 0.3 -0.1 -0.0 0.1 -0.2 1.4 0.1 0.1 0.3 0.3
Forced vital capacity (FVC), Best measure 1.7 6.1 18.7 0.6 1.6 -1.3 4.3 3.7 1.6 2.1 3.8 0.9 2.9 2.1 1.1 -3.0 -2.1
Body fat percentage 0.2 0.7 2.2 1.5 0.1 -0.3 -1.2 -0.6 -0.0 0.4 -1.2 -0.7 1.4 0.1 0.3 0.4 0.9
Leg fat percentage (right) 0.4 1.4 4.1 1.8 0.8 -1.1 -1.6 -0.7 0.6 1.0 -1.0 0.0 2.0 0.7 1.1 1.1 1.7
Arm fat-free mass (right) 0.2 1.0 3.0 0.1 -0.9 0.9 -0.5 0.7 -1.2 -0.5 -1.4 -1.7 1.3 -0.8 -0.9 -0.9 -0.8
Exposure to tobacco smoke outside home 0.3 0.5 2.0 0.2 -0.3 0.5 0.9 1.4 -0.4 0.1 0.4 -0.1 -0.8 -0.1 -0.4 -0.9 -1.1
Comparative body size at age 10 0.3 0.9 5.2 -0.7 -0.7 0.8 -1.2 -0.2 -1.1 -0.7 -2.3 -0.8 -0.1 -1.0 -0.6 0.7 0.5
Number of full brothers 0.7 0.8 2.5 -0.3 -0.7 0.6 -1.6 -1.6 -0.7 -1.2 -1.2 -0.9 -0.5 -0.9 -0.6 0.3 0.2
Worry too long after embarrassment 0.3 0.4 0.9 -0.5 -0.7 0.7 -0.5 -0.9 -0.5 -0.9 0.0 -0.3 -0.9 -0.7 -0.8 -0.1 -0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 2.1 2.8 6.7 1.2 1.8 -1.7 -0.2 -0.1 2.0 0.7 0.7 2.4 0.1 1.8 2.0 2.6 2.6
Wheeze or whistling in the chest in last year 2.3 4.1 7.3 2.6 -2.1 1.8 -2.6 -2.5 -1.8 -2.7 -1.5 -1.8 -2.2 -2.2 -1.8 1.1 0.3
Number of children fathered 0.4 0.4 1.0 -0.9 0.7 -0.9 0.3 1.0 0.8 0.4 0.0 0.6 0.0 0.7 0.6 0.2 0.9
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.2 2.8 -0.3 1.2 -1.4 -0.6 0.0 1.1 1.3 -0.1 1.6 0.5 1.1 1.4 1.1 1.7
Age at first live birth 1.6 2.9 9.0 0.6 -1.8 1.8 -1.6 -3.0 -1.9 -1.6 -1.7 -1.5 -1.8 -2.0 -1.7 0.5 -0.5
Pulse wave peak to peak time 1.1 1.3 2.8 0.8 -1.4 1.4 -0.0 -0.4 -1.2 -1.4 -0.1 -1.7 -0.4 -1.4 -1.6 -0.9 -1.4
Health satisfaction 0.2 0.2 0.7 -0.7 -0.4 0.3 -0.8 0.5 -0.6 -0.1 -0.8 -0.7 -0.1 -0.3 -0.2 -0.4 -0.3
Shortness of breath walking on level ground 1.3 1.6 2.6 0.3 -1.5 1.5 0.2 0.7 -1.5 -1.4 -0.3 -1.6 -1.4 -1.4 -1.5 -1.2 -1.6
Qualifications: College or University degree 0.3 0.9 3.0 -1.7 -0.6 0.8 -0.5 -1.3 -0.5 -0.9 -0.7 -0.0 -1.7 -0.8 -0.8 0.9 0.0
Eye problems/disorders: None of the above 0.9 1.1 9.7 -3.1 -0.2 0.7 -0.0 0.3 -0.4 -0.5 -1.3 0.3 -1.6 -0.2 -0.2 0.1 -0.2
Mouth/teeth dental problems: Loose teeth 0.5 0.6 3.0 1.7 0.3 -0.2 0.8 -0.2 0.3 0.2 1.7 0.5 0.1 0.5 0.1 -0.9 -0.7
Emphysema/chronic bronchitis 1.9 2.2 7.8 -0.8 0.8 -0.8 -2.3 -1.1 0.7 0.0 -1.5 0.6 -1.5 0.5 1.1 2.8 2.8
Medication for pain relief, constipation, heartburn 1.2 2.0 3.2 -1.7 -1.4 1.3 -0.8 -1.8 -1.3 -1.6 -1.3 -1.7 -1.6 -1.4 -1.4 -0.8 -1.2
Neck or shoulder pain in last month 0.3 0.4 0.9 -0.8 0.6 -0.7 -0.1 0.1 0.6 0.3 0.0 0.9 -0.8 0.5 0.7 0.8 0.9
Medication: Blood pressure 0.2 0.4 0.6 0.1 -0.6 0.6 -0.7 -0.4 -0.7 -0.6 -0.8 -0.5 -0.5 -0.7 -0.7 0.6 0.4
Angina (self-reported) 1.7 2.2 10.2 0.4 -0.1 0.1 2.5 3.2 0.1 0.7 2.1 -0.2 0.1 0.2 -0.4 -2.4 -1.9
Migraine (self-reported) 1.0 1.2 3.8 -0.1 1.3 -1.4 0.9 0.5 1.5 1.1 1.4 0.9 1.9 1.3 1.1 -0.0 0.3
Medication: Ibuprofen 0.6 0.7 2.5 0.6 -0.2 0.1 -1.5 -1.0 -0.3 -0.3 -0.9 0.4 -0.8 -0.4 -0.1 1.6 1.3
Medication: Allopurinol 0.2 0.2 1.1 1.0 -0.0 -0.2 -0.2 0.9 0.1 0.2 0.4 -0.6 0.7 0.1 0.1 -0.5 -0.2
Medication: Omeprazole 0.7 0.9 2.1 0.4 1.1 -1.3 0.4 1.4 1.1 0.9 0.7 0.9 -0.1 1.0 1.1 0.3 1.0
Medication: Seretide 50 evohaler 1.7 2.0 4.9 0.1 -1.3 1.5 -1.9 -1.2 -1.6 -1.4 -2.2 -1.3 -1.2 -1.6 -1.1 1.3 0.5
Mean time to correctly identify matches 1.2 2.2 4.1 0.7 1.7 -1.9 -0.0 -1.2 1.8 1.6 1.1 1.6 1.3 1.6 1.8 1.2 2.0
Heart disease (mother) 0.9 1.1 3.6 1.8 0.5 -0.4 1.8 0.9 0.6 0.9 1.9 0.8 1.0 0.7 0.4 -0.8 -0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.1 0.5 -0.7 -0.0 0.1 0.3 0.2 0.1 -0.2 0.1 0.3 -0.5 -0.1 -0.2 -0.0 -0.3
Whole body fat mass 0.2 0.7 2.4 1.2 -0.4 0.2 -1.2 -0.2 -0.6 0.0 -1.6 -1.3 1.5 -0.4 -0.2 -0.1 0.2
Leg fat mass (right) 0.2 0.8 3.8 1.4 0.2 -0.4 -1.4 -0.3 -0.1 0.4 -1.4 -0.8 1.9 0.2 0.4 0.4 0.9
Arm predicted mass (right) 0.2 0.8 2.3 -0.1 -0.7 0.8 -0.4 0.8 -1.0 -0.3 -1.4 -1.5 1.2 -0.6 -0.7 -0.8 -0.7
Pulse rate, automated reading 4.7 15.3 49.6 -1.8 4.4 -4.3 2.5 4.2 3.8 5.6 1.3 3.1 7.0 4.5 4.3 -0.4 1.9
Alcohol intake frequency. 0.1 0.3 1.1 -0.1 -0.5 0.5 0.5 0.5 -0.4 -0.2 0.0 -0.8 -1.0 -0.5 -0.5 -0.6 -0.6
Comparative height size at age 10 0.4 2.2 5.2 -0.4 -1.6 1.6 0.3 0.2 -1.7 -1.2 -0.5 -2.1 1.2 -1.4 -1.8 -2.3 -2.3
Number of full sisters 0.4 0.5 2.2 1.5 -0.1 -0.1 0.2 0.7 0.2 -0.0 1.0 -0.9 0.9 0.0 -0.1 -0.8 -0.8
Suffer from ‘nerves’ 1.2 1.9 3.3 -0.1 1.7 -1.6 0.1 0.3 1.8 1.7 0.6 1.8 1.0 1.7 1.7 1.4 1.7
Overall health rating 0.8 1.8 4.5 0.6 1.6 -1.6 0.7 1.1 1.5 2.1 0.8 1.5 1.2 1.7 1.6 0.4 1.3
Chest pain or discomfort 0.3 0.5 1.1 0.4 -0.6 0.5 -0.9 -1.1 -0.7 -0.5 -0.8 -0.9 -0.7 -0.8 -0.5 0.2 0.3
Had major operations 3.8 4.4 7.2 -0.7 2.7 -2.6 2.0 2.1 2.5 2.6 1.0 2.1 1.9 2.7 2.5 0.6 1.6
Age at last live birth 1.0 1.5 5.2 1.3 -1.3 1.3 -0.6 -2.3 -1.2 -1.5 -0.3 -1.0 -1.0 -1.3 -1.3 -0.2 -0.9
Family relationship satisfaction 0.3 0.3 4.0 2.0 -0.0 0.2 -0.2 0.5 -0.3 -0.1 0.4 0.4 0.2 -0.1 -0.1 0.0 -0.0
Leg pain on walking 2.7 3.4 10.2 0.2 1.5 -1.9 2.5 3.2 1.7 1.9 2.4 1.2 1.8 1.8 1.3 -1.8 -0.6
Qualifications: NVQ or HND or HNC or equivalent 1.0 1.3 3.5 0.5 1.1 -1.2 1.3 1.3 1.0 1.2 1.1 0.2 1.9 1.3 1.1 -1.0 -0.1
Commuting to job workplace: Car/motor vehicle 0.2 0.2 2.0 1.4 0.0 -0.0 0.1 -0.4 0.0 -0.2 -0.3 -0.2 0.6 0.1 0.1 0.3 0.3
Illness, injury, bereavement, stress in last 2 years 0.5 0.7 2.0 -0.4 -0.6 0.6 1.3 -0.0 -0.4 -0.4 0.9 -0.8 0.8 -0.4 -0.7 -1.2 -1.4
Medication: Aspirin 1.2 1.6 3.9 2.0 -1.5 1.7 0.1 0.3 -1.5 -1.4 0.1 -1.2 0.2 -1.4 -1.6 -0.8 -1.4
Supplements: Vitamin C 0.7 0.8 2.8 0.5 -0.6 0.3 -1.1 -1.7 -0.4 -1.1 -0.7 -0.6 -1.7 -0.8 -0.4 0.9 0.6
Knee pain experienced in last month 0.2 0.4 3.4 -0.4 0.1 -0.1 -0.1 0.9 0.0 0.4 0.2 0.6 -1.9 0.1 0.2 0.3 0.1
Hypertension (Self-reported) 0.7 2.0 4.7 1.5 1.5 -1.7 -0.5 -0.5 1.5 0.8 0.3 1.8 1.0 1.4 1.7 1.6 2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 1.0 0.1 0.7 -0.9 -0.0 -0.6 1.0 0.6 0.0 0.9 0.6 0.9 1.0 0.5 0.7
Illnesses of father: Heart disease 0.5 0.7 4.4 2.1 0.4 -0.4 0.8 0.6 0.4 0.5 1.3 0.4 0.5 0.5 0.3 -0.9 -0.5
Illnesses of siblings: Diabetes 0.3 0.4 1.4 1.2 -0.0 0.2 -1.0 0.0 -0.4 0.0 -1.1 -0.2 0.5 -0.0 0.2 0.7 0.9
Smoking status: Previous 0.4 0.6 3.4 0.8 0.5 -0.5 0.6 0.1 0.7 0.3 1.3 0.9 1.8 0.8 0.6 -0.2 0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 3.0 -1.1 -1.4 1.2 -0.5 -0.4 -1.2 -1.3 -0.9 -1.7 0.2 -1.2 -1.4 -0.9 -1.3
Whole body fat-free mass 0.4 2.1 5.5 -0.5 -1.5 1.7 -0.6 0.7 -1.9 -1.1 -1.8 -2.3 1.0 -1.4 -1.6 -1.4 -1.6
Leg fat-free mass (right) 0.3 1.7 5.0 -0.3 -1.4 1.6 -0.6 0.5 -1.7 -1.0 -1.7 -2.2 0.5 -1.3 -1.4 -1.1 -1.3
Arm fat percentage (left) 0.3 1.1 4.2 1.4 -0.3 0.2 -2.1 -0.9 -0.6 -0.1 -2.0 -1.0 0.6 -0.5 -0.1 0.9 1.0
Average weekly red wine intake 0.6 0.9 1.9 1.1 -1.0 1.2 -0.5 -1.4 -1.1 -1.3 -0.6 -0.9 -0.4 -1.1 -1.1 -0.3 -0.8
Handedness (chirality/laterality): Left-handed 0.5 0.6 2.3 -0.8 -0.4 0.4 0.7 1.5 -0.6 0.4 0.1 -0.8 -0.2 -0.3 -0.6 -1.4 -1.2
Mood swings 0.2 0.3 1.4 -0.3 0.6 -0.4 -0.0 0.6 0.5 -0.0 -0.4 0.7 0.5 0.6 0.6 1.2 0.8
Loneliness, isolation 0.9 1.2 4.2 0.6 0.3 -0.5 -1.5 -2.1 0.5 0.3 -0.9 0.6 -1.1 0.2 0.5 1.8 1.8
Long-standing illness, disability or infirmity 0.6 0.9 3.1 0.5 1.0 -1.1 -0.8 0.6 0.8 1.0 -0.2 1.0 -0.6 0.8 1.2 1.2 1.8
Ever had bowel cancer screening 0.2 0.3 1.2 1.1 -0.1 0.2 0.8 0.1 -0.1 0.2 0.9 0.1 0.1 0.1 -0.2 -0.8 -0.6
Diabetes diagnosed by doctor 0.6 0.9 2.6 1.6 -0.9 0.9 -0.4 1.3 -1.0 -0.7 -0.2 -1.5 0.3 -0.8 -0.8 -1.0 -0.8
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 0.8 0.4 0.6 -0.5 0.2 -0.5 0.7 0.4 0.9 0.8 -0.2 0.6 0.6 0.5 0.5
Friendships satisfaction 0.6 0.7 1.5 1.2 -1.0 1.0 -0.5 -0.4 -0.9 -0.9 0.2 -0.7 -0.8 -1.0 -1.1 -0.3 -0.9
Qualifications: nursing, teaching 0.2 0.2 0.8 -0.2 -0.2 0.5 -0.6 -0.7 -0.5 -0.1 -0.7 0.4 0.0 -0.4 -0.2 0.9 0.5
Commuting to job workplace: Walk 1.1 1.2 3.5 0.8 -1.1 1.0 0.8 0.4 -1.0 -0.9 0.9 -1.0 -0.3 -0.9 -1.3 -1.8 -1.9
Eye problems/disorders: Cataract 0.9 1.0 3.3 0.9 -1.2 1.1 -0.4 -1.8 -1.1 -1.0 -0.2 -1.2 -0.1 -1.1 -1.1 -0.4 -0.9
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 1.3 -0.3 0.8 -0.5 1.2 0.2 0.7 0.7 0.9 0.8 0.9 0.8 0.6 -0.0 0.2
Medication for cholesterol 0.1 0.1 0.6 -0.8 0.0 -0.1 0.6 -0.6 0.1 0.3 0.1 -0.0 -0.5 -0.1 -0.2 -0.2 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.4 1.7 3.6 -0.5 1.6 -1.3 -0.5 0.4 1.2 1.7 0.0 1.7 -0.5 1.3 1.6 1.7 1.9
Back pain experienced in last month 4.0 5.8 8.5 1.7 2.6 -2.7 1.9 2.9 2.6 2.6 2.8 2.7 2.8 2.8 2.6 0.0 1.1
Mineral and other dietary supplements 1.4 1.9 3.2 -0.8 -1.4 1.7 -1.3 -1.5 -1.4 -1.5 -1.7 -0.9 -1.8 -1.7 -1.5 0.6 -0.3
Breast cancer (self-reported) 0.4 0.5 4.2 -2.1 -0.1 0.0 -0.9 -0.4 -0.2 0.3 -1.4 -0.1 0.1 -0.1 0.1 0.3 0.4
Asthma (self-reported) 1.2 2.4 5.7 2.2 -1.4 1.2 -2.3 -2.4 -1.2 -1.6 -1.2 -1.2 -1.8 -1.5 -1.1 1.2 0.4
Osteoporosis (self-reported) 0.2 0.3 1.1 1.1 -0.5 0.7 -0.5 -0.1 -0.7 -0.1 -0.2 -0.5 -0.6 -0.5 -0.6 -0.1 -0.2
Osteoarthritis (self-reported) 0.9 1.1 3.9 0.9 0.1 0.1 -2.0 -1.3 0.0 -0.1 -0.9 0.6 -1.6 -0.0 0.5 1.8 1.4
Medication: Aspirin 0.5 0.6 2.0 1.4 -0.8 0.9 0.4 1.1 -0.9 -0.6 0.3 -0.6 0.4 -0.7 -0.9 -0.6 -0.9
Medication: Gliclazide 0.8 0.9 3.3 1.5 -0.5 0.4 -1.8 -1.2 -0.6 -0.5 -1.1 -0.4 -0.7 -0.8 -0.4 0.9 0.7
Illnesses of father: None of the above (group 1) 0.9 1.1 2.9 -0.9 0.4 -0.9 1.6 1.0 0.7 0.7 1.5 0.0 1.7 0.6 0.3 -1.7 -0.9
Smoking status: Current 0.6 1.0 2.4 1.5 0.6 -0.8 -1.0 -1.4 0.6 -0.0 0.0 0.9 -1.5 0.3 0.7 1.2 1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.4 2.9 6.9 -0.2 1.5 -1.4 2.6 2.6 1.5 2.1 1.9 1.2 2.1 1.8 1.4 -1.0 -0.5
Whole body water mass 0.4 2.2 5.7 -0.5 -1.6 1.8 -0.6 0.6 -2.0 -1.2 -1.9 -2.4 0.9 -1.5 -1.6 -1.4 -1.6
Leg predicted mass (right) 0.3 1.8 5.0 -0.3 -1.4 1.6 -0.6 0.4 -1.8 -1.1 -1.8 -2.2 0.5 -1.4 -1.5 -1.1 -1.4
Arm fat mass (left) 0.2 0.9 3.4 1.2 -0.6 0.5 -1.6 -0.4 -0.9 -0.3 -1.9 -1.3 1.1 -0.6 -0.4 0.3 0.4
Number of self-reported non-cancer illnesses 1.4 2.5 6.0 1.4 1.8 -1.9 -0.5 -0.1 1.8 1.2 0.4 2.0 1.0 1.7 1.9 1.8 2.5
Average weekly champagne plus white wine intake 2.1 2.8 9.5 -3.1 -1.5 1.4 -1.6 -2.1 -1.5 -1.7 -2.3 -1.2 -1.6 -1.6 -1.4 0.8 -0.3
Miserableness 0.3 0.6 1.9 -0.1 -0.9 0.8 0.5 -0.5 -0.7 -0.9 0.1 -0.9 -0.4 -0.7 -1.0 -0.8 -1.4
Guilty feelings 0.5 0.8 1.8 1.0 0.8 -0.8 -0.9 -1.4 1.0 0.6 0.4 1.0 0.5 0.7 0.9 1.1 1.0
Wears glasses or contact lenses 0.5 0.6 2.3 -0.8 -0.0 0.3 -0.7 -0.3 -0.4 0.0 -1.5 0.1 -1.5 -0.2 0.0 1.1 0.9
Ever taken oral contraceptive pill 2.6 2.9 5.4 1.4 -2.1 2.1 -1.0 -0.8 -2.3 -2.0 -0.8 -1.9 -1.3 -2.1 -2.1 -0.9 -1.4
Hearing aid user 2.0 2.2 6.5 -1.2 0.4 -0.4 -2.5 -1.1 0.2 -0.3 -2.5 0.5 -1.4 -0.1 0.6 2.5 2.5
Mother’s age at death 0.3 0.4 1.8 1.3 -0.5 0.3 -0.4 -0.7 -0.5 -0.6 -0.0 -0.7 0.6 -0.5 -0.6 -1.0 -0.5
Financial situation satisfaction 0.4 0.5 1.8 1.4 0.6 -0.4 0.6 1.2 0.6 0.9 0.7 0.4 0.4 0.6 0.6 -0.0 0.1
Tinnitus: Yes, now most or all of the time 0.3 0.3 1.3 -0.4 0.2 -0.4 -1.0 -1.1 0.2 0.2 -0.6 0.4 0.5 -0.0 0.3 0.5 0.7
Commuting to job workplace: Public transport 1.2 1.4 3.7 -0.0 -1.0 1.2 -1.7 -1.7 -1.1 -1.2 -1.3 -0.3 -1.9 -1.3 -0.9 0.9 0.0
Eye problems/disorders: Glaucoma 2.3 2.7 8.6 2.0 1.6 -1.8 0.1 0.1 1.7 1.8 1.2 2.0 2.9 1.4 1.4 1.2 1.7
Medication: Blood pressure 0.2 0.4 1.2 1.1 0.7 -0.9 -0.6 -0.1 0.6 0.4 0.2 0.4 0.8 0.7 0.9 0.2 0.8
Pain type(s) experienced in last month: Hip pain 0.2 0.3 0.9 -0.5 0.4 -0.7 0.3 0.2 0.8 0.2 1.0 0.6 -0.6 0.4 0.4 -0.0 0.1
Supplements: Fish oil (including cod liver oil) 0.7 0.9 2.4 0.2 0.8 -1.1 1.1 1.3 0.8 1.2 1.0 0.3 1.5 1.1 0.8 -0.7 0.0
High cholesterol (Self-reported) 0.5 0.9 1.8 0.5 -1.2 1.0 -0.8 -0.9 -1.0 -1.4 -0.9 -1.2 -1.0 -1.2 -1.1 -0.2 -0.4
Medication: Bendroflumethiazide 0.7 1.1 2.7 -0.0 -1.2 1.2 -0.9 -1.0 -1.3 -1.6 -1.1 -0.9 -1.0 -1.3 -1.0 0.1 -0.3
Medication: Paracetamol 3.1 4.8 8.3 0.7 2.6 -2.7 1.9 2.6 2.5 2.9 2.2 2.1 1.9 2.6 2.4 0.1 1.4
Medication: Lisinopril 0.3 0.3 2.6 1.6 0.2 -0.2 0.1 0.6 0.1 0.6 0.5 -0.0 0.8 0.2 0.1 -0.5 -0.1
Medication: Atorvastatin 0.9 1.2 2.1 0.7 -1.2 1.4 -0.6 -0.1 -1.4 -1.2 -0.5 -1.3 -0.1 -1.3 -1.4 -1.0 -1.2
Illnesses of father: High blood pressure 1.1 1.4 2.7 1.2 -1.4 1.6 -0.9 0.1 -1.5 -1.6 -0.7 -1.5 -0.7 -1.3 -1.4 -0.2 -0.9
Alcohol drinker status: Never 1.4 1.7 3.1 1.6 -1.5 1.8 -0.7 -1.0 -1.4 -1.7 -0.5 -1.0 -1.6 -1.6 -1.5 0.4 -0.7
Ever smoked 0.6 1.0 2.8 0.9 0.8 -1.0 -1.0 -1.0 1.0 0.3 0.4 1.7 0.6 0.7 1.0 1.3 1.5
Basal metabolic rate 0.4 2.0 5.4 -0.2 -1.5 1.6 -0.8 0.5 -1.9 -1.0 -1.8 -2.3 1.0 -1.4 -1.5 -1.2 -1.4
Leg fat percentage (left) 0.4 1.4 3.6 1.9 0.7 -1.0 -1.7 -0.7 0.5 0.9 -1.2 -0.1 1.9 0.5 1.0 1.1 1.7
Arm fat-free mass (left) 0.2 1.2 3.2 -0.2 -1.0 1.2 -0.4 0.6 -1.4 -0.7 -1.5 -1.8 1.4 -0.9 -1.0 -1.0 -1.1
Number of operations (self-reported) 1.3 2.0 3.6 -0.0 1.8 -1.8 1.3 1.4 1.7 1.9 1.0 1.2 1.4 1.9 1.7 0.0 0.8
Average weekly beer plus cider intake 1.0 1.4 4.0 0.7 1.3 -1.2 1.1 1.4 1.1 1.5 1.2 0.9 2.0 1.4 1.2 -0.4 0.3
Irritability 0.8 1.4 3.9 -0.2 1.4 -1.1 0.2 -0.0 1.4 0.9 0.3 1.9 0.4 1.3 1.4 2.0 1.7
Risk taking 1.3 1.8 5.1 1.3 -0.9 1.0 -2.3 -1.6 -1.2 -1.2 -1.7 -0.8 -2.0 -1.2 -0.6 1.3 0.8
Ever had prostate specific antigen (PSA) test 1.6 1.8 5.0 2.2 1.1 -1.2 1.7 0.6 1.3 1.4 2.0 1.0 1.6 1.4 1.0 -0.9 -0.1
Fractured/broken bones in last 5 years 2.1 2.7 4.5 -1.8 2.0 -2.0 1.3 1.2 2.1 2.0 0.9 1.9 0.9 2.1 2.0 0.6 1.1
Age started oral contraceptive pill 0.2 0.2 0.5 -0.1 -0.5 0.5 -0.7 -0.5 -0.5 -0.4 -0.1 -0.4 -0.1 -0.7 -0.6 0.1 -0.2
Diastolic blood pressure, automated reading 0.3 1.1 4.1 -0.9 0.9 -1.1 -0.7 -0.9 0.7 1.3 -0.9 0.4 2.0 0.8 1.0 0.6 1.2
Ever depressed for a whole week 0.1 0.2 0.6 0.8 0.2 -0.1 -0.2 0.3 0.3 -0.3 0.6 0.7 -0.4 0.3 0.2 0.2 0.2
Unable to work because of sickness or disability 0.1 0.1 0.4 0.5 -0.0 0.1 -0.1 -0.3 0.0 -0.1 0.2 0.5 -0.1 -0.0 0.0 0.6 0.4
Commuting to job workplace: Cycle 0.3 0.4 1.1 -0.2 -0.7 1.0 0.1 0.2 -0.8 -0.3 -0.3 -1.1 -0.0 -0.7 -0.8 -0.5 -0.9
Myopia 6.0 8.7 15.4 1.4 -3.6 3.5 -0.3 -1.5 -3.4 -3.4 -0.6 -3.8 -1.9 -3.4 -3.8 -3.1 -3.9
Vascular/heart problems diagnosed by doctor 0.7 2.0 3.6 -1.7 -1.6 1.6 0.1 -0.2 -1.6 -1.2 -0.6 -1.8 -1.4 -1.5 -1.7 -1.3 -1.9
Cholesterol lowering medication 0.8 1.2 3.0 1.4 0.9 -0.8 1.1 1.7 0.8 0.9 1.3 0.4 1.7 1.1 0.9 -0.9 -0.3
Medication: Omeprazole (e.g. Zanprol) 0.8 1.0 2.4 1.2 0.9 -1.2 0.6 1.5 1.1 0.9 1.1 0.9 0.2 0.9 1.0 0.2 0.8
Pain experienced in last month 4.2 7.0 12.3 0.7 -3.3 3.5 -1.6 -2.3 -3.5 -3.1 -2.6 -3.4 -1.2 -3.4 -3.2 -0.6 -1.8
Supplements: Calcium 0.8 0.9 1.9 0.9 0.8 -1.2 0.8 0.7 1.2 0.9 1.4 1.1 1.1 1.1 0.9 -0.1 0.3
Basal cell carcinoma (self-reported) 1.0 1.2 4.9 0.2 0.4 -0.7 1.7 0.8 0.9 0.5 2.2 0.2 1.5 0.5 0.1 -1.5 -1.1
Heart attack/myocardial infarction (self-reported) 0.3 0.4 0.6 0.4 0.8 -0.6 -0.4 0.6 0.5 0.7 0.4 0.8 0.6 0.6 0.6 0.4 0.7
Deep venous thrombosis (DVT) (self-reported) 0.1 0.2 0.5 0.6 -0.2 0.2 -0.7 -0.2 -0.2 -0.6 -0.3 -0.4 -0.5 -0.3 -0.3 -0.4 -0.2
Heart disease (siblings) 0.3 0.3 1.1 0.3 0.3 -0.3 1.1 1.0 0.4 0.1 0.8 0.3 0.0 0.4 0.2 -0.9 -0.5
Alcohol drinker status: Previous 0.3 0.3 1.6 0.0 -0.1 0.4 1.1 0.7 -0.2 0.1 0.5 0.4 -1.3 -0.1 -0.3 -0.6 -0.4
Pack years of smoking 0.4 0.6 2.4 0.1 0.6 -0.5 -1.0 -1.1 0.6 0.2 -0.6 0.2 -0.4 0.3 0.7 1.5 1.4
Impedance of whole body 0.2 1.0 4.7 0.6 0.8 -1.0 1.5 0.1 1.2 0.9 2.2 1.0 0.3 1.0 0.7 -0.8 -0.4
Leg fat mass (left) 0.2 0.8 3.6 1.4 0.1 -0.3 -1.3 -0.4 -0.2 0.3 -1.4 -0.9 1.9 0.0 0.3 0.3 0.7
Arm predicted mass (left) 0.3 1.5 4.1 -0.3 -1.2 1.3 -0.6 0.5 -1.6 -0.8 -1.7 -2.0 1.3 -1.1 -1.2 -1.0 -1.1