Best TWAS P=3.08e-12 · Best GWAS P=3.73e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | USP14 | 0.11 | 0.05 | bslmm | 400 | 0.07 | 1.5e-08 | 6.9 | -6.4 | 1.6e-10 | -0.76 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Tibial | USP14 | 0.11 | 0.07 | lasso | 2 | 0.06 | 1.9e-05 | 6.9 | 6.9 | 4.4e-12 | 0.98 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Nerve Tibial | USP14 | 0.19 | 0.13 | enet | 16 | 0.12 | 5.2e-09 | 6.9 | 6.6 | 5.7e-11 | 0.95 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Stomach | USP14 | 0.17 | 0.05 | lasso | 2 | 0.04 | 5.3e-03 | 6.9 | 6.9 | 5.7e-12 | 0.96 | 0.01 | 0.97 | FALSE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | USP14 | 0.18 | 0.08 | enet | 22 | 0.16 | 1.0e-20 | 3.2 | -5.7 | 1.2e-08 | -0.49 | 1.00 | 0.00 | FALSE |
| 6 | YFS | Blood | USP14 | 0.08 | 0.07 | enet | 11 | 0.07 | 5.0e-23 | 6.9 | -7.0 | 3.1e-12 | -0.95 | 0.00 | 1.00 | TRUE |