Best TWAS P=1.47e-11 · Best GWAS P=9.21e-13 conditioned to 0.00345
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | SOGA2 | 0.14 | 0.09 | lasso | 5 | 0.08 | 1.2e-06 | -6.1 | -6.1 | 1.3e-09 | 0.89 | 0.28 | 0.72 | FALSE |
| 2 | GTEx | Nerve Tibial | SOGA2 | 0.17 | 0.08 | lasso | 7 | 0.05 | 1.5e-04 | -6.6 | 6.6 | 4.0e-11 | -0.78 | 0.08 | 0.87 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | SOGA2 | 0.09 | 0.04 | lasso | 6 | 0.04 | 2.1e-06 | -6.6 | 6.8 | 1.5e-11 | -0.80 | 0.02 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | KIAA0802 | 0.06 | 0.04 | lasso | 6 | 0.04 | 1.6e-09 | -5.1 | -5.8 | 6.8e-09 | 0.82 | 0.06 | 0.94 | FALSE |