[Hub]/) : Traits : Lung FVC : ← →

chr17:78,778,692-81,051,007

Best TWAS P=3.58e-25 · Best GWAS P=1.8e-26 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DCXR	0.14	0.07	enet	17	0.10	3.4e-12	8.6	9.8	9.1e-23	0.79	0.06	0.94	TRUE
2	CommonMind	Brain Pre-frontal Cortex	MYADML2	0.52	0.43	enet	15	0.45	3.6e-60	-6.4	-6.9	5.5e-12	-0.27	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	RAC3	0.09	0.05	enet	10	0.07	2.2e-08	9.8	9.1	1.1e-19	0.79	0.00	1.00	FALSE
4	GTEx	Adrenal Gland	DCXR	0.38	0.18	lasso	4	0.20	1.2e-07	9.4	9.7	2.8e-22	0.80	0.09	0.90	TRUE
5	GTEx	Artery Aorta	DCXR	0.34	0.17	enet	25	0.21	1.4e-11	9.4	9.3	9.9e-21	0.70	0.75	0.25	FALSE
6	GTEx	Artery Tibial	STRA13	0.37	0.22	enet	14	0.22	1.6e-17	3.1	-5.4	8.3e-08	-0.53	1.00	0.00	TRUE
7	GTEx	Artery Tibial	DCXR	0.28	0.21	lasso	5	0.21	3.1e-16	9.4	10.3	1.2e-24	0.89	0.58	0.42	FALSE
8	GTEx	Brain Cerebellum	DCXR	0.20	0.23	lasso	3	0.22	4.5e-07	9.4	9.4	6.3e-21	0.77	0.07	0.80	FALSE
9	GTEx	Breast Mammary Tissue (Female)	CCDC57	0.10	0.00	enet	12	0.01	1.7e-01	3.1	5.8	5.2e-09	0.46	0.03	0.22	TRUE
10	GTEx	Cells EBV-transformed lymphocytes	DCXR	0.29	0.24	lasso	2	0.20	3.8e-07	8.6	9.0	2.5e-19	0.75	0.33	0.60	FALSE
11	GTEx	Esophagus Muscularis	DCXR	0.18	0.08	lasso	5	0.05	9.2e-04	9.4	10.2	3.0e-24	0.86	0.02	0.98	FALSE
12	GTEx	Nerve Tibial	DCXR	0.19	0.06	enet	20	0.10	1.4e-07	8.6	8.7	2.2e-18	0.75	0.01	0.98	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	DCXR	0.12	0.00	enet	13	0.00	2.3e-01	9.4	7.7	1.4e-14	0.65	0.02	0.74	FALSE
14	GTEx	Skin Sun Exposed Lower leg	DCXR	0.08	0.11	lasso	7	0.09	4.6e-08	9.4	9.6	1.2e-21	0.80	0.15	0.85	TRUE
15	GTEx	Thyroid	ASPSCR1	0.23	0.15	enet	19	0.09	1.2e-07	-6.9	7.8	7.8e-15	0.35	1.00	0.00	TRUE
16	GTEx	Thyroid	DCXR	0.35	0.20	lasso	5	0.30	5.1e-23	9.4	9.0	2.3e-19	0.77	0.68	0.32	FALSE
17	NTR	Blood	ACTG1	0.04	0.00	blup	260	0.02	4.2e-06	4.0	-5.2	2.0e-07	0.05	0.00	0.08	TRUE
18	YFS	Blood	ASPSCR1	0.11	0.07	lasso	9	0.06	7.9e-20	-6.6	7.3	3.2e-13	0.27	1.00	0.00	FALSE
19	YFS	Blood	LRRC45	0.01	0.00	lasso	1	0.00	1.3e-02	9.4	9.4	5.1e-21	0.79	0.01	0.81	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PYCR1	0.02	0.01	blup	9	0.01	1.1e-02	-6.4	7.3	3.3e-13	0.27	0.01	0.40	TRUE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DCXR	0.04	0.04	lasso	4	0.02	1.6e-03	7.8	7.9	2.1e-15	0.61	0.20	0.27	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	GPS1	0.04	0.02	blup	43	0.01	1.5e-02	2.8	-5.2	2.5e-07	-0.47	0.15	0.07	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	MYADML2	0.03	0.03	blup	10	0.03	1.1e-04	-6.7	-7.1	9.1e-13	-0.28	0.01	0.96	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	NOTUM	0.06	0.02	enet	2	0.02	4.7e-03	-6.2	-6.9	4.3e-12	-0.27	0.02	0.26	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	NPB	0.03	0.01	enet	3	0.01	1.1e-02	-6.9	6.6	3.9e-11	0.27	0.00	0.91	FALSE
26	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	METRNL	0.05	0.02	blup	27	0.03	4.6e-03	-2.3	-5.3	9.2e-08	-0.03	0.00	0.09	TRUE
27	The Cancer Genome Atlas	Thyroid Carcinoma	DCXR	0.09	0.03	blup	38	0.09	9.5e-09	9.4	10.4	3.6e-25	0.83	0.01	0.99	TRUE