Best TWAS P=1.29e-08 · Best GWAS P=2.23e-07 conditioned to 0.0277
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | XRN2 | 0.06 | 0.03 | bslmm | 414 | 0.02 | 1.3e-03 | 4.7 | 5.7 | 1.3e-08 | 0.60 | 0.06 | 0.91 | TRUE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PLK1S1 | 0.19 | 0.12 | enet | 14 | 0.13 | 4.3e-13 | 4.2 | 5.3 | 1.4e-07 | 0.67 | 0.28 | 0.62 | FALSE |