Best TWAS P=1.75e-12 · Best GWAS P=9.29e-30 conditioned to 3.57e-15
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | EYA2 | 0.42 | 0.32 | lasso | 6 | 0.34 | 1.6e-19 | 7.5 | -7.0 | 1.8e-12 | -0.43 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Thyroid | EYA2 | 0.29 | 0.16 | enet | 51 | 0.15 | 1.0e-11 | -1.3 | -5.3 | 1.4e-07 | -0.12 | 1.00 | 0.00 | FALSE |
| 3 | METSIM | Adipose | EYA2 | 0.05 | 0.01 | enet | 21 | 0.03 | 6.6e-05 | 8.5 | -5.3 | 1.3e-07 | -0.34 | 0.45 | 0.08 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | EYA2 | 0.36 | 0.14 | enet | 18 | 0.28 | 9.0e-28 | -1.3 | -6.0 | 2.4e-09 | -0.24 | 1.00 | 0.00 | TRUE |